Scientific evidence invalidates health assumptions underlying the FCC and ICNIRP exposure limit determinations for radiofrequency radiation: implications for 5G.

International Commission on the Biological Effects of Electromagnetic Fields (ICBE-EMF)
Author Information

Abstract

In the late-1990s, the FCC and ICNIRP adopted radiofrequency radiation (RFR) exposure limits to protect the public and workers from adverse effects of RFR. These limits were based on results from behavioral studies conducted in the 1980s involving 40-60-minute exposures in 5 monkeys and 8 rats, and then applying arbitrary safety factors to an apparent threshold specific absorption rate (SAR) of 4���W/kg. The limits were also based on two major assumptions: any biological effects were due to excessive tissue heating and no effects would occur below the putative threshold SAR, as well as twelve assumptions that were not specified by either the FCC or ICNIRP. In this paper, we show how the past 25���years of extensive research on RFR demonstrates that the assumptions underlying the FCC's and ICNIRP's exposure limits are invalid and continue to present a public health harm. Adverse effects observed at exposures below the assumed threshold SAR include non-thermal induction of reactive oxygen species, DNA damage, cardiomyopathy, carcinogenicity, sperm damage, and neurological effects, including electromagnetic hypersensitivity. Also, multiple human studies have found statistically significant associations between RFR exposure and increased brain and thyroid cancer risk. Yet, in 2020, and in light of the body of evidence reviewed in this article, the FCC and ICNIRP reaffirmed the same limits that were established in the 1990s. Consequently, these exposure limits, which are based on false suppositions, do not adequately protect workers, children, hypersensitive individuals, and the general population from short-term or long-term RFR exposures. Thus, urgently needed are health protective exposure limits for humans and the environment. These limits must be based on scientific evidence rather than on erroneous assumptions, especially given the increasing worldwide exposures of people and the environment to RFR, including novel forms of radiation from 5G telecommunications for which there are no adequate health effects studies.

Keywords

References

  1. Toxicol Lett. 2020 May 1;323:35-40 [PMID: 31991167]
  2. Environ Mol Mutagen. 2020 Feb;61(2):276-290 [PMID: 31633839]
  3. Ann N Y Acad Sci. 1975 Feb 28;247:433-9 [PMID: 46734]
  4. Metab Brain Dis. 2015 Oct;30(5):1193-206 [PMID: 26033310]
  5. Electromagn Biol Med. 2012 Sep;31(3):213-22 [PMID: 22897402]
  6. Tumour Biol. 2014 Jan;35(1):581-7 [PMID: 23975478]
  7. Environ Int. 2014 Sep;70:106-12 [PMID: 24927498]
  8. Bioelectromagnetics. 2008 Oct;29(7):527-38 [PMID: 18452168]
  9. Electromagn Biol Med. 2021 Apr 3;40(2):264-273 [PMID: 33539186]
  10. Neurotox Res. 2020 Jun;38(1):105-123 [PMID: 32200527]
  11. Toxicology. 2007 Apr 11;232(3):311-6 [PMID: 17336440]
  12. Bioelectromagnetics. 1986;7(3):315-28 [PMID: 3753534]
  13. Exp Eye Res. 1987 Sep;45(3):357-73 [PMID: 3666062]
  14. Health Phys. 1998 Apr;74(4):494-522 [PMID: 9525427]
  15. J Microw Power. 1977 Dec;12(4):369-81 [PMID: 249342]
  16. PLoS One. 2015 May 15;10(5):e0124728 [PMID: 25978736]
  17. Phys Med Biol. 1996 Nov;41(11):2251-69 [PMID: 8938025]
  18. Nature. 2014 May 15;509(7500):353-6 [PMID: 24805233]
  19. Phys Med Biol. 2009 Jan 21;54(2):227-41 [PMID: 19088390]
  20. Environ Pollut. 2020 Dec;267:115632 [PMID: 33254645]
  21. Bioelectromagnetics. 2003 Jan;24(1):39-48 [PMID: 12483664]
  22. Int J Mol Sci. 2021 Apr 06;22(7): [PMID: 33917298]
  23. J Chem Neuroanat. 2016 Sep;75(Pt B):123-7 [PMID: 26723545]
  24. Br J Cancer. 2005 Oct 3;93(7):842-8 [PMID: 16136046]
  25. Int J Mol Med. 2010 Aug;26(2):301-6 [PMID: 20596612]
  26. Environ Res. 2018 Aug;165:496-503 [PMID: 29530389]
  27. Electromagn Biol Med. 2006;25(4):349-60 [PMID: 17178592]
  28. Mutat Res. 2005 Oct 15;578(1-2):149-57 [PMID: 15935405]
  29. Bioelectromagnetics. 2003;Suppl 6:S39-62 [PMID: 14628306]
  30. Environ Res. 2018 Nov;167:694-699 [PMID: 29884550]
  31. Pathophysiology. 2011 Jun;18(3):193-9 [PMID: 21112192]
  32. World Neurosurg. 2012 Mar-Apr;77(3-4):518-24 [PMID: 22120376]
  33. Zhonghua Nan Ke Xue. 2019 May;25(5):451-455 [PMID: 32216233]
  34. PLoS One. 2007 Sep 26;2(9):e937 [PMID: 17895978]
  35. Environ Health. 2021 Jul 17;20(1):84 [PMID: 34273995]
  36. Indian J Exp Biol. 2012 Dec;50(12):889-96 [PMID: 23986973]
  37. Toxicol Ind Health. 2016 Jun;32(6):968-79 [PMID: 24604340]
  38. Bioelectromagnetics. 2003 Sep;24(6):387-94 [PMID: 12929157]
  39. Bioelectromagnetics. 2018 Dec;39(8):617-630 [PMID: 30383885]
  40. Science. 1982 Nov 26;218(4575):916-8 [PMID: 7134985]
  41. Natl Toxicol Program Tech Rep Ser. 2018 Nov;(596): [PMID: 33562896]
  42. Hum Exp Toxicol. 2012 Jul;31(7):734-40 [PMID: 22249391]
  43. Epidemiology. 2014 Mar;25(2):233-41 [PMID: 24434752]
  44. Bioelectromagnetics. 2004 Sep;25(6):441-51 [PMID: 15300730]
  45. F1000Res. 2013 Feb 12;2:40 [PMID: 24327874]
  46. J Biomed Opt. 2008 Jul-Aug;13(4):044030 [PMID: 19021357]
  47. Pathophysiology. 2015 Mar;22(1):1-13 [PMID: 25466607]
  48. Allergy. 2005 Jun;60(6):838-9 [PMID: 15876318]
  49. Int J Radiat Biol. 2012 Apr;88(4):367-73 [PMID: 22145622]
  50. Toxicol Ind Health. 2017 Apr;33(4):373-384 [PMID: 27738269]
  51. Neural Regen Res. 2012 Jun 5;7(16):1248-55 [PMID: 25709623]
  52. J Natl Cancer Inst. 2001 Feb 7;93(3):203-7 [PMID: 11158188]
  53. IEEE Trans Electromagn Compat. 2017 Dec;59(6):1798-1808 [PMID: 29217849]
  54. Environ Toxicol. 2008 Jun;23(3):319-27 [PMID: 18214898]
  55. Am J Epidemiol. 2017 Oct 1;186(7):885-893 [PMID: 28535174]
  56. Brain Res. 2015 Mar 19;1601:92-101 [PMID: 25598203]
  57. Bioelectromagnetics. 2010 Jan;31(1):1-11 [PMID: 19681059]
  58. Occup Environ Med. 2014 Jul;71(7):514-22 [PMID: 24816517]
  59. Health Phys. 2016 Dec;111(6):528-541 [PMID: 27798477]
  60. Microsc Res Tech. 1994 Apr 15;27(6):535-42 [PMID: 8012056]
  61. Reprod Biomed Online. 2015 Sep;31(3):421-6 [PMID: 26206279]
  62. Chin Med J (Engl). 2018 Feb 20;131(4):402-412 [PMID: 29451144]
  63. Biol Lett. 2014 Jun;10(6): [PMID: 24899681]
  64. Bioelectromagnetics. 2015 Jan;36(1):45-54 [PMID: 25399679]
  65. Int J Oncol. 2021 Nov;59(5): [PMID: 34617575]
  66. Curr Biol. 2014 Feb 17;24(4):446-50 [PMID: 24508165]
  67. J Environ Public Health. 2018 Jun 24;2018:7910754 [PMID: 30034480]
  68. J Med Eng Technol. 2002 Jul-Aug;26(4):168-72 [PMID: 12396332]
  69. Neuroepidemiology. 2013;40(2):101-8 [PMID: 23095687]
  70. Environ Pollut. 2021 Aug 1;282:116952 [PMID: 33862271]
  71. Cancer Epidemiol. 2011 Oct;35(5):453-64 [PMID: 21862434]
  72. Electromagn Biol Med. 2007;26(1):63-72 [PMID: 17454083]
  73. Ire Trans Biomed Electron. 1962 Apr;BME-9:104-8 [PMID: 14037410]
  74. Bioelectromagnetics. 1992;13(4):247-59 [PMID: 1510735]
  75. J Adv Res. 2013 Mar;4(2):181-7 [PMID: 25685416]
  76. Environ Res. 2021 Nov;202:111784 [PMID: 34333014]
  77. Exp Oncol. 2018 Dec;40(4):282-287 [PMID: 30593748]
  78. Rare Tumors. 2014 Aug 08;6(3):5350 [PMID: 25276320]
  79. Biochem Soc Trans. 2007 Nov;35(Pt 5):1147-50 [PMID: 17956298]
  80. Environ Health Perspect. 2016 Jun;124(6):713-21 [PMID: 26600562]
  81. Pathophysiology. 2013 Apr;20(2):117-22 [PMID: 23557856]
  82. Environ Health Perspect. 2005 Sep;113(9):1172-7 [PMID: 16140623]
  83. Front Behav Neurosci. 2016 Mar 22;10:55 [PMID: 27047356]
  84. Bioelectromagnetics. 2004 Sep;25(6):431-40 [PMID: 15300729]
  85. Bioelectromagnetics. 1998;19(7):393-413 [PMID: 9771583]
  86. Health Phys. 2007 Jun;92(6):591-5 [PMID: 17495660]
  87. Biochem Biophys Res Commun. 2002 Oct 18;298(1):95-102 [PMID: 12379225]
  88. Health Phys. 2020 May;118(5):477-482 [PMID: 32251080]
  89. Electromagn Biol Med. 2010 Jun;29(1-2):31-5 [PMID: 20560769]
  90. Reprod Biol Endocrinol. 2018 Dec 9;16(1):118 [PMID: 30445985]
  91. Bioelectromagnetics. 1994;15(2):163-76 [PMID: 8024607]
  92. Naturwissenschaften. 2004 Dec;91(12):585-8 [PMID: 15551029]
  93. Rev Environ Health. 2021 Jul 08;37(3):327-406 [PMID: 34243228]
  94. Bioelectromagnetics. 2018 Apr;39(3):190-199 [PMID: 29537695]
  95. J Med Eng Technol. 2006 Sep-Oct;30(5):306-9 [PMID: 16980285]
  96. Fertil Steril. 2009 Oct;92(4):1318-1325 [PMID: 18804757]
  97. Natl Toxicol Program Tech Rep Ser. 2018 Nov;(595): [PMID: 33562898]
  98. Ann Epidemiol. 2019 Jan;29:39-45 [PMID: 30446214]
  99. Electromagn Biol Med. 2008;27(3):215-29 [PMID: 18821198]
  100. Electromagn Biol Med. 2011 Dec;30(4):253-60 [PMID: 22047463]
  101. Rev Environ Health. 2013;28(2-3):75-84 [PMID: 24192494]
  102. J Neurosci Res. 2009 May 1;87(6):1484-99 [PMID: 19115403]
  103. Biochem Biophys Res Commun. 2015 Apr 17;459(4):585-90 [PMID: 25749340]
  104. Rev Environ Health. 2022 Mar 02;38(2):219-228 [PMID: 35238501]
  105. Phys Med Biol. 2010 Apr 7;55(7):1767-83 [PMID: 20208098]
  106. Int J Oncol. 2013 Oct;43(4):1036-44 [PMID: 23877578]
  107. Health Phys. 2020 May;118(5):483-524 [PMID: 32167495]
  108. Int J Radiat Biol. 2013 Mar;89(3):147-54 [PMID: 23078358]
  109. Andrologia. 2019 Apr;51(3):e13201 [PMID: 30461041]
  110. Indian J Biochem Biophys. 2013 Apr;50(2):114-9 [PMID: 23720885]
  111. J Occup Environ Hyg. 2015;12 Suppl 1:S55-68 [PMID: 26097979]
  112. Int J Mol Sci. 2020 Mar 11;21(6): [PMID: 32168876]
  113. J Androl. 2012 May-Jun;33(3):350-6 [PMID: 21799142]
  114. Cell Biochem Biophys. 2013 Mar;65(2):85-96 [PMID: 22926544]
  115. Sci Total Environ. 2020 Jan 1;698:133860 [PMID: 31514029]
  116. Health Phys. 2020 Jun;118(6):678-682 [PMID: 32345908]
  117. Brain Res. 2010 Jan 22;1311:189-96 [PMID: 19879861]
  118. J Neurophysiol. 2018 Dec 1;120(6):2719-2729 [PMID: 30133383]
  119. PLoS One. 2009 Jul 31;4(7):e6446 [PMID: 19649291]
  120. Electromagn Biol Med. 2012 Jun;31(2):151-65 [PMID: 22268919]
  121. Bioelectromagnetics. 2009 Feb;30(2):129-41 [PMID: 18839414]
  122. Environ Health Perspect. 2010 Mar;118(3):394-9 [PMID: 20064781]
  123. Front Public Health. 2018 Sep 21;6:270 [PMID: 30298125]
  124. PLoS One. 2017 Oct 4;12(10):e0185461 [PMID: 28976991]
  125. Bioelectromagnetics. 2011 Feb;32(2):85-93 [PMID: 21225885]
  126. Biochem J. 2007 Aug 1;405(3):559-68 [PMID: 17456048]
  127. Neurol Res. 2014 Dec;36(12):1072-9 [PMID: 24861496]
  128. Electromagn Biol Med. 2012 Mar;31(1):34-51 [PMID: 21999884]
  129. Aviat Space Environ Med. 1994 May;65(5 Suppl):A116-20 [PMID: 8018070]
  130. Pathophysiology. 2010 Jun;17(3):179-87 [PMID: 19954937]
  131. BMC Cancer. 2016 Jul 07;16:426 [PMID: 27388603]
  132. PLoS One. 2008 Feb 27;3(2):e1676 [PMID: 18301753]
  133. Environ Res. 2018 May;163:123-133 [PMID: 29433020]
  134. J Exp Biol. 2020 Feb 25;223(Pt 4): [PMID: 32029460]
  135. J Microw Power. 1979 Dec;14(4):351-62 [PMID: 261597]
  136. Pathophysiology. 2009 Aug;16(2-3):205-16 [PMID: 19264460]
  137. Bioelectromagnetics. 1980;1(2):183-98 [PMID: 7284023]
  138. Health Phys. 2020 May;118(5):525-532 [PMID: 31464775]
  139. Rev Environ Health. 2016 Sep 1;31(3):363-97 [PMID: 27454111]
  140. Int J Epidemiol. 2010 Jun;39(3):675-94 [PMID: 20483835]
  141. Sci Rep. 2019 Nov 25;9(1):17478 [PMID: 31767903]
  142. Environ Res. 2020 Jul;186:109445 [PMID: 32289567]
  143. Bioelectromagnetics. 1984;5(2):233-46 [PMID: 6732879]
  144. Bioelectromagnetics. 1996;17(3):230-41 [PMID: 8809363]
  145. Sci Total Environ. 2019 Apr 15;661:553-562 [PMID: 30682608]
  146. Cancer Manag Res. 2020 Oct 29;12:10799-10807 [PMID: 33149685]
  147. Neurotoxicology. 2011 Aug;32(4):478-94 [PMID: 21524663]
  148. Electromagn Biol Med. 2018;37(2):66-75 [PMID: 29667447]
  149. Health Phys. 2002 Apr;82(4):540-8 [PMID: 11906144]
  150. Lancet Planet Health. 2018 Dec;2(12):e512-e514 [PMID: 30526934]
  151. Ups J Med Sci. 2010 May;115(2):91-6 [PMID: 20095879]
  152. Int J Environ Res Public Health. 2020 Dec 07;17(23): [PMID: 33297463]
  153. Exp Oncol. 2013 Sep;35(3):219-25 [PMID: 24084462]
  154. Bioelectromagnetics. 2008 Apr;29(3):219-32 [PMID: 18044737]
  155. Electromagn Biol Med. 2016;35(2):186-202 [PMID: 26151230]
  156. Electromagn Biol Med. 2019;38(1):32-47 [PMID: 30669883]
  157. Neuron. 2004 Mar 4;41(5):683-6 [PMID: 15003168]
  158. Ann N Y Acad Sci. 1992 Mar 31;649:356-8 [PMID: 1580510]
  159. Bioelectromagnetics. 1982;3(2):227-35 [PMID: 7126275]
  160. Reprod Toxicol. 2021 Mar;100:90-100 [PMID: 33497741]
  161. J R Soc Interface. 2015 Feb 6;12(103): [PMID: 25540238]
  162. Rev Environ Health. 2021 May 27;37(1):81-122 [PMID: 34047144]
  163. IARC Monogr Eval Carcinog Risks Hum. 2013;102(Pt 2):1-460 [PMID: 24772662]
  164. Rev Environ Health. 2012;27(1):51-8 [PMID: 22755267]
  165. Opt Express. 2015 Oct 5;23(20):26604-16 [PMID: 26480173]
  166. Indian J Exp Biol. 2010 Oct;48(10):987-92 [PMID: 21299041]
  167. Sci Rep. 2012;2:312 [PMID: 22428084]
  168. Neurol Sci. 2013 Jul;34(7):1117-24 [PMID: 22976773]
  169. Neuroreport. 2007 May 28;18(8):803-7 [PMID: 17471070]
  170. Bioelectromagnetics. 1992;13(6):469-96 [PMID: 1482413]
  171. Int J Radiat Biol. 2010 Jul;86(7):529-41 [PMID: 20545575]
  172. Bioelectromagnetics. 2002 Jan;23(1):26-36 [PMID: 11793403]
  173. Int J Neurosci. 2011 Dec;121(12):670-6 [PMID: 21793784]
  174. Curr Med Chem. 2003 Dec;10(23):2495-505 [PMID: 14529465]
  175. Environ Res. 2020 Mar;182:109013 [PMID: 31918310]
  176. Pathophysiology. 2009 Aug;16(2-3):103-12 [PMID: 19345073]
  177. Radiat Res. 1985 Apr;102(1):59-70 [PMID: 3983370]
  178. Electromagn Biol Med. 2007;26(2):141-51 [PMID: 17613041]
  179. J R Soc Interface. 2017 Aug;14(133): [PMID: 28794163]
  180. Bioelectromagnetics. 2016 Jan;37(1):14-24 [PMID: 26369906]
  181. Health Phys. 2018 Dec;115(6):705-711 [PMID: 30247338]
  182. Int J Fertil Steril. 2015 Apr-Jun;9(1):129-36 [PMID: 25918601]
  183. Histol Histopathol. 2022 Mar;37(3):287-299 [PMID: 34854072]
  184. Bratisl Lek Listy. 2014;115(5):260-6 [PMID: 25174055]
  185. Biomed Environ Sci. 2002 Dec;15(4):283-90 [PMID: 12642984]
  186. J Invest Dermatol. 1981 Jul;77(1):13-9 [PMID: 7252245]
  187. Neurotoxicology. 2006 Jul;27(4):534-46 [PMID: 16620992]
  188. Sci Rep. 2018 Mar 2;8(1):3924 [PMID: 29500425]
  189. Behav Neurosci. 2014 Oct;128(5):633-7 [PMID: 24999587]

MeSH Term

Animals
Cell Phone
Child
Humans
Male
Radiation Exposure
Radio Waves
Rats
Reactive Oxygen Species
Semen

Chemicals

Reactive Oxygen Species

Word Cloud

Created with Highcharts 10.0.0limitsRFReffectsexposureFCCICNIRPhealthradiationbasedexposuresassumptionsstudiesthresholdSARdamageevidence5GradiofrequencyprotectpublicworkersunderlyingoxygenspeciesDNAincludingenvironmentScientificphone*Exposurelate-1990sadoptedadverseresultsbehavioralconducted1980sinvolving40-60-minute5monkeys8ratsapplyingarbitrarysafetyfactorsapparentspecificabsorptionrate4���W/kgalsotwomajorassumptions:biologicaldueexcessivetissueheatingoccurputativewelltwelvespecifiedeitherpapershowpast25���yearsextensiveresearchdemonstratesFCC'sICNIRP'sinvalidcontinuepresentharmAdverseobservedassumedincludenon-thermalinductionreactivecardiomyopathycarcinogenicityspermneurologicalelectromagnetichypersensitivityAlsomultiplehumanfoundstatisticallysignificantassociationsincreasedbrainthyroidcancerriskYet2020lightbodyreviewedarticlereaffirmedestablished1990sConsequentlyfalsesuppositionsadequatelychildrenhypersensitiveindividualsgeneralpopulationshort-termlong-termThusurgentlyneededprotectivehumansmustscientificrathererroneousespeciallygivenincreasingworldwidepeoplenovelformstelecommunicationsadequateinvalidateslimitdeterminationsradiation:implicationsCellassessmentFederalCommunicationsCommissionInternationalcommissionnon-ionizingprotectionMobileRadiationRadiofrequencyReactiveROSintegrity

Similar Articles

Cited By