Only one study among U.S. prison staff has explored the effects of work-family conflict and job burnout. To replicate the research to determine whether the results vary by nation, this study examined the effects of four types of work-family conflict (strain-based, time-based, behavior-based and family-based conflict) on three dimensions of job burnout (emotional exhaustion, depersonalization and feeling ineffective at work) among Nigerian correctional staff. Strain- and behavior-based conflict had significant positive effects on emotional exhaustion, but time- and family-based conflict did not. Family-based conflict was the only type of domain spillover with significant positive effects on depersonalization. Behavior-based conflict was the only type of work-family conflict with significant positive effects on feeling ineffective at work. Time-based and strain-based conflict were highly related to one another, which was attributed to time-based conflict being a contributor to strain-based conflict for Nigerian prison staff.