Narasimha Rao Bandaru: Department of Chemistry, GITAM School of Science, GITAM Deemed to be University Hyderabad, Rudraram 502329, India.
Parameshwar Makam: Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University, Arcadia Grant, Chandanwari, Premnagar, Dehradun 248007, India.
Parameswari Akshinthala: Department of Science and Humanities, MLR Institute of Technology, Dundigal, Medchal, Hyderabad, Rudraram 500043, India.
Naresh Kumar Katari: Department of Chemistry, GITAM School of Science, GITAM Deemed to be University Hyderabad, Rudraram 502329, India. ORCID
Venkanna Banoth: Department of Biotechnology, University Post Graduate College of Science and Technology, Jawaharlal Nehru Technological University Hyderabad, Rudraram 500085, India.
Balakrishna Kolli: Department of Chemistry, GITAM School of Science, GITAM Deemed to be University Hyderabad, Rudraram 502329, India. ORCID
Rambabu Gundla: Department of Chemistry, GITAM School of Science, GITAM Deemed to be University Hyderabad, Rudraram 502329, India.
Antimicrobial resistance is on the rise, and there aren't enough new treatments to combat it. This might send the modern world back to the pre-antibiotic age. The molecular hybrids of pyrazolo[3,4-]pyridine and triazole have been designed, synthesized, and analyzed for their drug-like molecule nature and in vitro analyses for their inhibition potentials against and . The compounds and have been identified as the high potential molecules in this series based on in vitro experiments. Compound has zone of inhibition values of 15 ± 0.82 mm and 14 ± 0.7 mm, whilst compound has zone of inhibition values of 18 ± 0.95 mm and 16 ± 0.82 mm against and , respectively. MIC and MIB values for compounds and against and are 0.25 and 0.5, respectively.
