[PCR for COVID in the transplant protocol].

Esmeralda Campos-Aguirre, Julio César Martínez-Álvarez, María Araceli Arrazola-García, Oscar David Arroyo-García, María Guadalupe Delgado-Colín, Miguel Ángel Chávez-Durán, Alexis Ignacio Galván-Bobadilla, Gamaliel Benítez-Arvizu
Author Information
  1. Esmeralda Campos-Aguirre: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID
  2. Julio César Martínez-Álvarez: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID
  3. María Araceli Arrazola-García: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID
  4. Oscar David Arroyo-García: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID
  5. María Guadalupe Delgado-Colín: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID
  6. Miguel Ángel Chávez-Durán: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID
  7. Alexis Ignacio Galván-Bobadilla: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID
  8. Gamaliel Benítez-Arvizu: Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad Complementaria Banco de Sangre. Ciudad de México, México. ORCID

Abstract

Background: Since the beginning of the SARS-CoV-2 pandemic, identifying the COVID-19 pathophysiology not only has been addressed to applying diagnostic tests or preventing through vaccines, but also to the timely detection, especially of patients in risk groups such as those in transplants areas (renal, hematology, etcetera). In the case of these patients, using RT-PCR tests avoids putting them at risk by subjecting them to states of immunosuppression that could aggravate their situation if they were faced with an onset of a COVID-19 infection.
Objective: To present the results of patients of a transplant unit tested for SARS-CoV-2.
Material and methods: Descriptive, observational, cross-sectional, and retrolective study. Data of results of RT-PCR tests of patients who underwent transplantation from June 2021 to April 2022 in a third level hospital were collected.
Results: 755 tests were done to patients who underwent transplantation. 384 (50.8%) were women. Out of all patients, only 73 (9.7%) were positive to SARS-CoV-2.
Conclusions: Implementing RT-PCR tests as a transplant protocol to detect SARS-CoV-2 prevents fatal complications due to COVID infection to donors and receptors.

Keywords

References

  1. Nature. 2020 Mar;579(7798):270-273 [PMID: 32015507]
  2. N Engl J Med. 2020 Mar 26;382(13):1199-1207 [PMID: 31995857]
  3. Blood Adv. 2021 Dec 14;5(23):5140-5149 [PMID: 34581754]
  4. Trends Mol Med. 2020 May;26(5):483-495 [PMID: 32359479]
  5. Nat Med. 2021 Jan;27(1):28-33 [PMID: 33442016]
  6. J Am Soc Nephrol. 2020 Oct;31(10):2413-2423 [PMID: 32847984]
  7. PLoS One. 2020 Jun 26;15(6):e0235460 [PMID: 32589687]
  8. Expert Rev Hematol. 2021 Jan;14(1):1-5 [PMID: 33280467]
  9. Am J Transplant. 2020 Nov;20(11):3019-3029 [PMID: 32627319]
  10. Lab Invest. 2022 Jan;102(1):4-13 [PMID: 34497366]
  11. J Clin Lab Anal. 2022 Jan;36(1):e24178 [PMID: 34921443]
  12. Transplant Cell Ther. 2021 Mar;27(3):270.e1-270.e6 [PMID: 33781537]
  13. J Transl Med. 2021 Apr 8;19(1):145 [PMID: 33832504]
  14. Viruses. 2020 May 26;12(6): [PMID: 32466458]
  15. Transpl Infect Dis. 2021 Oct;23(5):e13738 [PMID: 34590768]
  16. J Clin Pathol. 2021 Apr;74(4):207-208 [PMID: 32631944]
  17. PLoS One. 2020 Dec 10;15(12):e0242958 [PMID: 33301459]
  18. J Clin Med. 2020 Apr 24;9(4): [PMID: 32344679]
  19. BMJ. 2020 Jul 1;370:m2516 [PMID: 32611558]
  20. Mucosal Immunol. 2022 Feb;15(2):198-210 [PMID: 34711920]
  21. Infection. 2021 Dec;49(6):1265-1275 [PMID: 34611792]
  22. Radiology. 2020 Aug;296(2):E32-E40 [PMID: 32101510]
  23. Am J Transplant. 2020 Jul;20(7):1819-1825 [PMID: 32351040]
  24. ACS Cent Sci. 2020 May 27;6(5):591-605 [PMID: 32382657]
  25. Emerg Microbes Infect. 2020 Dec;9(1):747-756 [PMID: 32196430]

MeSH Term

Humans
Female
Male
SARS-CoV-2
COVID-19
Cross-Sectional Studies
Pandemics
Polymerase Chain Reaction

Word Cloud

Created with Highcharts 10.0.0patientstestsSARS-CoV-2RT-PCRtransplantCOVID-19riskinfectionresultsunderwenttransplantationCOVIDBackground:SincebeginningpandemicidentifyingpathophysiologyaddressedapplyingdiagnosticpreventingvaccinesalsotimelydetectionespeciallygroupstransplantsareasrenalhematologyetceteracaseusingavoidsputtingsubjectingstatesimmunosuppressionaggravatesituationfacedonsetObjective:presentunittestedMaterialmethods:Descriptiveobservationalcross-sectionalretrolectivestudyDataJune2021April2022thirdlevelhospitalcollectedResults:755done384508%women7397%positiveConclusions:Implementingprotocoldetectpreventsfatalcomplicationsduedonorsreceptors[PCRprotocol]CoronavirusInfectionsPolymeraseChainReactionTransplantation

Similar Articles

Cited By