Prenatal Exposure to Ambient PM and Early Childhood Growth Impairment Risk in East Africa.

Kayan Clarke, Adriana C Rivas, Salvatore Milletich, Tara Sabo-Attwood, Eric S Coker
Author Information
  1. Kayan Clarke: Department of Environmental and Global Health, University of Florida, Gainesville, FL 32611, USA.
  2. Adriana C Rivas: Department of Environmental and Global Health, University of Florida, Gainesville, FL 32611, USA.
  3. Salvatore Milletich: Department of Environmental and Global Health, University of Florida, Gainesville, FL 32611, USA.
  4. Tara Sabo-Attwood: Department of Environmental and Global Health, University of Florida, Gainesville, FL 32611, USA.
  5. Eric S Coker: Department of Environmental and Global Health, University of Florida, Gainesville, FL 32611, USA.

Abstract

Height for age is an important and widely used population-level indicator of children's health. Morbidity trends show that stunting in young children is a significant public health concern. Recent studies point to environmental factors as an understudied area of child growth failure in Africa. Data on child measurements of height-for-age and confounders were obtained from fifteen waves of the Demographic and Health Surveys (DHS) for six countries in East Africa. Monthly ambient PM concentration data was retrieved from the Atmospheric Composition Analysis Group (ACAG) global surface PM estimates and spatially integrated with DHS data. Generalized additive models with linear and logistic regression were used to estimate the exposure-response relationship between prenatal PM and height-for-age and stunting among children under five in East Africa (EA). Fully adjusted models showed that for each 10 µg/m increase in PM concentration there is a 0.069 (CI: 0.097, 0.041) standard deviation decrease in height-for-age and 9% higher odds of being stunted. Our study identified ambient PM as an environmental risk factor for lower height-for-age among young children in EA. This underscores the need to address emissions of harmful air pollutants in EA as adverse health effects are attributable to ambient PM air pollution.

Keywords

References

Am J Clin Nutr. 2020 Sep 14;112(Suppl 2):860S-874S [PMID: 32778881]
Int J Occup Environ Med. 2019 Jan;10(1):17-29 [PMID: 30685774]
Food Nutr Bull. 2014 Jun;35(2):167-78 [PMID: 25076764]
Environ Res. 2002 Sep;90(1):12-20 [PMID: 12359186]
Environ Sci Technol. 2021 Nov 16;55(22):15287-15300 [PMID: 34724610]
Future Child. 1997 Summer-Fall;7(2):149-56 [PMID: 9299843]
Int J Epidemiol. 2009 Oct;38(5):1351-63 [PMID: 19759098]
Environ Int. 2020 Sep;142:105862 [PMID: 32599351]
Arch Public Health. 2021 Nov 12;79(1):196 [PMID: 34772469]
PLoS One. 2013 Sep 16;8(9):e73784 [PMID: 24066070]
PLoS One. 2014 Dec 02;9(12):e113920 [PMID: 25463771]
Science. 2009 May 22;324(5930):1035-44 [PMID: 19407144]
BMJ. 2014 Jan 24;348:f7450 [PMID: 24464277]
Lancet Planet Health. 2021 Oct;5(10):e681-e688 [PMID: 34627472]
J Nutr. 2014 May;144(5):765-70 [PMID: 24598879]
Epidemiology. 2017 Mar;28(2):207-214 [PMID: 28005571]
Environ Health Perspect. 2006 Mar;114(3):373-8 [PMID: 16507460]
Int J Environ Res Public Health. 2017 Dec 23;15(1): [PMID: 29295507]
Microcirculation. 2019 Nov;26(8):e12526 [PMID: 30597690]
PLoS One. 2021 Mar 25;16(3):e0248637 [PMID: 33765094]
Environ Int. 2018 Apr;113:122-132 [PMID: 29421401]
Front Cardiovasc Med. 2022 Jan 11;8:784800 [PMID: 35087881]
Matern Child Nutr. 2018 Nov;14 Suppl 4:e12517 [PMID: 29048726]
Am J Epidemiol. 2016 Aug 15;184(4):302-14 [PMID: 27519539]
Int J Epidemiol. 2009 Oct;38(5):1342-50 [PMID: 19622677]
Int J Epidemiol. 2007 Feb;36(1):117-29 [PMID: 17085456]
Inhal Toxicol. 2010 Jun;22 Suppl 1:1-19 [PMID: 20462389]
Environ Sci Technol. 2021 Mar 2;55(5):2790-2799 [PMID: 33417434]
Environ Sci Technol. 2020 Jul 7;54(13):7879-7890 [PMID: 32491847]
BMC Public Health. 2022 Sep 12;22(1):1723 [PMID: 36089579]
J Dev Orig Health Dis. 2021 Feb;12(1):6-33 [PMID: 31902390]
Epidemiology. 2014 Nov;25(6):913-6 [PMID: 25210928]
BMJ Open. 2021 Dec 20;11(12):e052267 [PMID: 34930735]
Sci Rep. 2015 Jul 29;5:12467 [PMID: 26219273]
Environ Res. 2021 Aug;199:111352 [PMID: 34043968]
Environ Health Perspect. 2005 Apr;113(4):375-82 [PMID: 15811825]
J Thorac Dis. 2016 Jan;8(1):E8-E19 [PMID: 26904258]
BMC Pediatr. 2015 Oct 21;15:165 [PMID: 26489405]
BMC Pediatr. 2015 Dec 16;15:212 [PMID: 26675579]
Environ Health. 2019 Jul 9;18(1):62 [PMID: 31288809]
Lancet Glob Health. 2020 Apr;8(4):e472-e475 [PMID: 32199113]
PLoS Med. 2021 Sep 28;18(9):e1003718 [PMID: 34582444]
Ann Glob Health. 2018 Nov 05;84(4):551-562 [PMID: 30779500]
J Thorac Dis. 2016 Jan;8(1):E69-74 [PMID: 26904255]
PLoS One. 2012;7(2):e31743 [PMID: 22363717]
Health Econ Rev. 2015 Dec;5(1):34 [PMID: 26603158]

Word Cloud

Similar Articles

Cited By