East Africa was not exempt from the devastating effects of COVID-19, which led to the nearly complete cessation of social and economic activities worldwide. The objective of this study was to predict mortality due to COVID-19 using an artificial intelligence-driven ensemble model in East Africa. The dataset, which spans two years, was divided into training and verification datasets. To predict the mortality, three steps were conducted, which included a sensitivity analysis, the modelling of four single AI-driven models, and development of four ensemble models. Four dominant input variables were selected to conduct the single models. Hence, the coefficients of determination of ANFIS, FFNN, SVM, and MLR were 0.9273, 0.8586, 0.8490, and 0.7956, respectively. The non-linear ensemble approaches performed better than the linear approaches, and the ANFIS ensemble was the best-performing ensemble approach that boosted the predicting performance of the single AI-driven models. This fact revealed the promising capability of ensemble models for predicting the daily mortality due to COVID-19 in other parts of the globe.
