Glucose and Fructose Supplementation and Their Acute Effects on Anaerobic Endurance and Resistance Exercise Performance in Healthy Individuals: A Double-Blind Randomized Placebo-Controlled Crossover Trial.

Max L Eckstein, Maximilian P Erlmann, Felix Aberer, Sandra Haupt, Paul Zimmermann, Nadine B Wachsmuth, Janis Schierbauer, Rebecca T Zimmer, Daniel Herz, Barbara Obermayer-Pietsch, Othmar Moser
Author Information
  1. Max L Eckstein: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.
  2. Maximilian P Erlmann: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.
  3. Felix Aberer: Department of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria. ORCID
  4. Sandra Haupt: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.
  5. Paul Zimmermann: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.
  6. Nadine B Wachsmuth: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.
  7. Janis Schierbauer: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany. ORCID
  8. Rebecca T Zimmer: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.
  9. Daniel Herz: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.
  10. Barbara Obermayer-Pietsch: Department of Internal Medicine, Division of Endocrinology and Diabetology, Endocrinology Lab Platform, Medical University of Graz, 8036 Graz, Austria. ORCID
  11. Othmar Moser: BaySpo-Bayreuth Center of Sport Science, Division of Exercise Physiology and Metabolism, University of Bayreuth, 95440 Bayreuth, Germany.

Abstract

BACKGROUND: The effects of glucose, fructose and a combination of these on physical performance have been subject of investigation, resulting in diverse findings.
OBJECTIVE: The aim of this study was to investigate how an individualized amount of glucose, fructose, and a combination of these compared to placebo (sucralose) alter endurance performance on a cycle ergometer, lower and upper body resistance exercise performance at individualized thresholds in healthy young individuals.
METHODS: A total of 16 healthy adults (9 females) with an age of 23.8 ± 1.6 years and a BMI of 22.6 ± 1.8 kg/m (body mass (BM) 70.9 ± 10.8 kg, height 1.76 ± 0.08 m) participated in this study. During the screening visit, the lactate turn point 2 (LTP2) was defined and the weights for chest-press and leg-press were determined. Furthermore, 30 min prior to each exercise session, participants received either 1 g/kg BM of glucose (Glu), 1 g/kg BM of fructose (Fru), 0.5 g/kg BM of glucose/fructose (GluFru) (each), or 0.2 g sucralose (placebo), respectively, which were dissolved in 300 mL of water. All exercises were performed until volitional exhaustion. Time until exhaustion (TTE) and cardio-pulmonary variables were determined for all cycling visits; during resistance exercise, repetitions until muscular failure were counted and time was measured. During all visits, capillary blood glucose and blood lactate concentrations as well as venous insulin levels were measured.
RESULTS: TTE in cycling was 449 ± 163 s (s) (Glu), 443 ± 156 s (Fru), 429 ± 160 s (GluFru) and 466 ± 162 s (Pla) ( = 0.48). TTE during chest-press sessions was 180 ± 95 s (Glu), 180 ± 92 s (Fru), 172 ± 78 s (GluFru) and 162 ± 66 s (Pla) ( = 0.25), respectively.
CONCLUSIONS: Pre-exercise supplementation of Glu, Fru and a combination of these did not have an ergogenic effect on high-intensity anaerobic endurance performance and on upper and lower body moderate resistance exercise in comparison to placebo.

Keywords

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Grants

  1. 491183248/Deutsche Forschungsgemeinschaft

MeSH Term

Adult
Female
Humans
Young Adult
Fructose
Glucose
Physical Endurance
Resistance Training
Double-Blind Method
Lactic Acid
Cross-Over Studies

Chemicals

Fructose
Glucose
Lactic Acid

Word Cloud

Created with Highcharts 10.0.0±sexerciseglucose10fructoseperformanceresistanceBMGluFrucombinationplacebobody8lactateg/kgGluFruTTEcyclingstudyindividualizedsucraloseendurancelowerupperhealthy962chest-pressdeterminedrespectivelyexhaustioncardio-pulmonaryvisitsmeasuredblood162Pla=180BACKGROUND:effectsphysicalsubjectinvestigationresultingdiversefindingsOBJECTIVE:aiminvestigateamountcomparedaltercycleergometerthresholdsyoungindividualsMETHODS:total16adultsfemalesage23yearsBMI22kg/mmass7010kgheight7608mparticipatedscreeningvisitturnpointLTP2definedweightsleg-pressFurthermore30minpriorsessionparticipantsreceivedeither5glucose/fructosegdissolved300mLwaterexercisesperformedvolitionalTimevariablesrepetitionsmuscularfailurecountedtimecapillaryconcentrationswellvenousinsulinlevelsRESULTS:44916344315642916046648sessions9592172786625CONCLUSIONS:Pre-exercisesupplementationergogeniceffecthigh-intensityanaerobicmoderatecomparisonGlucoseFructoseSupplementationAcuteEffectsAnaerobicEnduranceResistanceExercisePerformanceHealthyIndividuals:Double-BlindRandomizedPlacebo-ControlledCrossoverTrialtestingmetabolism

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