OpenLB
Open Library of Bioscience

Review on the Developments of Benzothiazole-containing Antimicrobial Agents.

Abstract

Keywords

References

1. Saha M.; Sarkar A.; Review on multiple facets of drug resistance: a rising challenge in the 21st century. J Xenobiot 2021,11(4),197-214 [DOI: 10.3390/jox11040013]
2. Ventola C.L.; The antibiotic resistance crisis: part 1: causes and threats. P [PMID: 25859123]
3. Dadgostar P.; Antimicrobial resistance: implications and costs. Infect Drug Resist 2019,12,3903-3910 [DOI: 10.2147/IDR.S234610]
4. Chaudhuri S.; Ghosh A.; Chattopadhyay S.K.; Green synthetic approaches for medium ring-sized heterocycles of biological and pharmaceutical interest. Green Synthetic Approaches for Biologically Relevant Heterocycles 2021,617-653 [DOI: 10.1016/B978-0-12-820792-5.00004-4]
5. Sharma P.C.; Sinhmar A.; Sharma A.; Rajak H.; Pathak D.P.; Medicinal significance of benzothiazole scaffold: an insight view. J Enzyme Inhib Med Chem 2013,28(2),240-266 [DOI: 10.3109/14756366.2012.720572]
6. Kok S.H.L.; Gambari R.; Chui C.H.; Yuen M.C.W.; Lin E.; Wong R.S.M.; Lau F.Y.; Cheng G.Y.M.; Lam W.S.; Chan S.H.; Lam K.H.; Cheng C.H.; Lai P.B.; Yu M.W.; Cheung F.; Tang J.C.; Chan A.S.; Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell lines. Bioorg Med Chem 2008,16(7),3626-3631 [DOI: 10.1016/j.bmc.2008.02.005]
7. Huang S.T.; Hsei I.J.; Chen C.; Synthesis and anticancer evaluation of bis(benzimidazoles), bis(benzoxazoles), and benzothiazoles. Bioorg Med Chem 2006,14(17),6106-6119 [DOI: 10.1016/j.bmc.2006.05.007]
8. Ismail M.A.H.; Tratrat C.; Haroun M.G.; Molecular modelling design, synthesis and cytotoxic evaluation of certain substituted 2-(3,4,5-triacetoxybenzoylamino)benzo[d]thiazole and 2-(galloylami-no)benzo[d]thiazole derivatives having potential topoisomerase-I inhibitory activity. J Enzyme Inhib Med Chem 2013,28(6),1331-1345 [DOI: 10.3109/14756366.2012.716835]
9. Irfan A.; Batool F.; Zahra Naqvi S.A.; Islam A.; Osman S.M.; Nocentini A.; Alissa S.A.; Supuran C.T.; Benzothiazole derivatives as anticancer agents. J Enzyme Inhib Med Chem 2020,35(1),265-279 [DOI: 10.1080/14756366.2019.1698036]
10. Su X.; Vicker N.; Ganeshapillai D.; Smith A.; Purohit A.; Reed M.J.; Potter B.V.L.; Benzothiazole derivatives as novel inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. Mol Cell Endocrinol 2006,248(1-2),214-217 [DOI: 10.1016/j.mce.2005.10.022]
11. Moreno-Díaz H.; Villalobos-Molina R.; Ortiz-Andrade R.; Díaz-Coutiño D.; Medina-Franco J.L.; Webster S.P.; Binnie M.; Estrada-Soto S.; Ibarra-Barajas M.; León-Rivera I.; Navarrete-Vázquez G.; Antidiabetic activity of N-(6-substituted-1,3-benzothiazol-2-yl)benzenesulfonamides. Bioorg Med Chem Lett 2008,18(9),2871-2877 [DOI: 10.1016/j.bmcl.2008.03.086]
12. Haroun M.; Novel hybrids of pyrazolidinedione and benzothiazole as TZD analogues. rationale design, synthesis and in vivo anti-diabetic evaluation. Med Chem 2019,15(6),624-633 [DOI: 10.2174/1573406415666190515093657]
13. Haroun M.; In silico Design, Synthesis and evaluation of novel series of benzothiazole- based pyrazolidinediones as potent hypoglycemic Agents. Med Chem 2020,16(6),812-825 [DOI: 10.2174/1573406416666191227113716]
14. Haroun M.; Petrou A.; Tratrat C.; Kositsi K.; Gavalas A.; Geronikaki A.; Venugopala K.N.; Sreeharsha N.; Discovery of benzothiazole-based thiazolidinones as potential anti-inflammatory agents: anti-inflammatory activity, soybean lipoxygenase inhibition effect and molecular docking studies. SAR QSAR Environ Res 2022,33(6),485-497 [DOI: 10.1080/1062936X.2022.2084772]
15. Doğruer D.S.; Ünlü S.; Şahin M.F.; Yqilada E.; Anti-nociceptive and anti-inflammatory activity of some (2-benzoxazolone-3-yl and 2-benzothiazolone-3-yl) acetic acid derivatives. Farmaco 1998,53(1),80-84 [DOI: 10.1016/S0014-827X(97)00017-7]
16. Venugopala K.N.; Khedr M.A.; Pillay M.; Nayak S.K.; Chandrashekharappa S.; Aldhubiab B.E.; Harsha S.; Attimard M.; Odhav B.; Benzothiazole analogs as potential anti-TB agents: computational input and molecular dynamics. J Biomol Struct Dyn 2019,37(7),1830-1842 [DOI: 10.1080/07391102.2018.1470035]
17. Venugopala K.N.; Chandrashekharappa S.; Pillay M.; Bhandary S.; Kandeel M.; Mahomoodally F.M.; Morsy M.A.; Chopra D.; Aldhubiab B.E.; Attimarad M.; Alwassil O.I.; Harsha S.; Mlisana K.; Odhav B.; Synthesis and structural elucidation of novel benzothiazole derivatives as anti-tubercular agents: In-silico screening for possible target identification. Med Chem 2019,15(3),311-326 [DOI: 10.2174/1573406414666180703121815]
18. Moodley R.; Mashaba C.; Rakodi G.; Ncube N.; Maphoru M.; Balogun M.; Jordan A.; Warner D.; Khan R.; Tukulula M.; New quinoline-urea-benzothiazole hybrids as promising antitubercular agents: synthesis, in vitro antitubercular activity, cytotoxicity studies, and in silico ADME profiling. Pharmaceuticals (Basel) 2022,15(5),576 [DOI: 10.3390/ph15050576]
19. Ke S.; Wei Y.; Yang Z.; Wang K.; Liang Y.; Shi L.; Novel cycloalkylthiophene-imine derivatives bearing benzothiazole scaffold: Synthesis, characterization and antiviral activity evaluation. Bioorg Med Chem Lett 2013,23(18),5131-5134 [DOI: 10.1016/j.bmcl.2013.07.023]
20. Vicini P.; Geronikaki A.; Incerti M.; Busonera B.; Poni G.; Cabras C.A.; La Colla P.; Synthesis and biological evaluation of benzo[d]isothiazole, benzothiazole and thiazole Schiff bases. Bioorg Med Chem 2003,11(22),4785-4789 [DOI: 10.1016/S0968-0896(03)00493-0]
21. Nagarajan S.R.; De Crescenzo G.A.; Getman D.P.; Lu H.F.; Sikorski J.A.; Walker J.L.; McDonald J.J.; Houseman K.A.; Kocan G.P.; Kishore N.; Mehta P.P.; Funkes-Shippy C.L.; Blystone L.; Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease. Bioorg Med Chem 2003,11(22),4769-4777 [DOI: 10.1016/j.bmc.2003.07.001]
22. Haroun M.; Tratrat C.; Petrou A.; Geronikaki A.; Ivanov M.; Ciric A.; Sokovic M.; 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. Bioorg Med Chem Lett 2021,32,127718 [DOI: 10.1016/j.bmcl.2020.127718]
23. Haroun M.; Tratrat C.; Kositzi K.; Tsolaki E.; Petrou A.; Aldhubiab B.; Attimarad M.; Harsha S.; Geronikaki A.; Venugopala K.N.; Elsewedy H.S.; Sokovic M.; Glamoclija J.; Ciric A.; New benzothiazole-based thiazolidinones as potent antimicrobial agents. Design, synthesis and biological evaluation. Curr Top Med Chem 2018,18(1),75-87 [DOI: 10.2174/1568026618666180206101814]
24. Tratrat C.; novel thiazole-based thiazolidinones as potent anti-infective agents: in silico pass and toxicity prediction, synthesis, biological evaluation and molecular modelling. Comb Chem High Throughput Screen 2020,23(2),126-140 [DOI: 10.2174/1386207323666200127115238]
25. Herrera Cano N.; Ballari M.S.; López A.G.; Santiago A.N.; New synthesis and biological evaluation of benzothiazole derivates as antifungal agents. J Agric Food Chem 2015,63(14),3681-3686 [DOI: 10.1021/acs.jafc.5b00150]
26. Liu Y.; Wang Y.; Dong G.; Zhang Y.; Wu S.; Miao Z.; Yao J.; Zhang W.; Sheng C.; Novel benzothiazole derivatives with a broad antifungal spectrum: design, synthesis and structure-activity relationships. MedChemComm 2013,4(12),1551-1561 [DOI: 10.1039/c3md00215b]
27. Jimonet P.; Audiau F.; Barreau M.; Blanchard J.C.; Boireau A.; Bour Y.; Coléno M.A.; Doble A.; Doerflinger G.; Do Huu C.; Donat M.H.; Duchesne J.M.; Ganil P.; Guérémy C.; Honoré E.; Just B.; Kerphirique R.; Gontier S.; Hubert P.; Laduron P.M.; Le Blevec J.; Meunier M.; Miquet J.M.; Nemecek C.; Pasquet M.; Piot O.; Pratt J.; Rataud J.; Reibaud M.; Stutzmann J-M.; Mignani S.; Riluzole series. Synthesis and in vivo “antiglutamate” activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines. J Med Chem 1999,42(15),2828-2843 [DOI: 10.1021/jm980202u]
28. Benazzouz A.; Boraud T.; Dubédat P.; Boireau A.; Stutzmann J.M.; Gross C.; Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study. Eur J Pharmacol 1995,284(3),299-307 [DOI: 10.1016/0014-2999(95)00362-O]
29. Neres J.; Brewer M.L.; Ratier L.; Botti H.; Buschiazzo A.; Edwards P.N.; Mortenson P.N.; Charlton M.H.; Alzari P.M.; Frasch A.C.; Bryce R.A.; Douglas K.T.; Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening. Bioorg Med Chem Lett 2009,19(3),589-596 [DOI: 10.1016/j.bmcl.2008.12.065]
30. Sreenivasa G.; Jayachandran E.; Shivakumar B.; Jayaraj K.; Vijay K.; Synthesis of bioactive molecule fluoro benzothiazole comprising potent heterocyclic moieties for anthelmintic activity. Arch Pharm Sci Res 2009,1,150-157
31. Gao X.; Liu J.; Zuo X.; Feng X.; Gao Y.; Recent advances in synthesis of benzothiazole compounds related to green chemistry. Molecules 2020,25(7),1675 [DOI: 10.3390/molecules25071675]
32. Maddila S.; Gorle S.; Seshadri N.; Lavanya P.; Jonnalagadda S.B.; Synthesis, antibacterial and antifungal activity of novel benzothiazole pyrimidine derivatives. Arab J Chem 2016,9(5),681-687 [DOI: 10.1016/j.arabjc.2013.04.003]
33. Abood Z.H.; Qabel H.A.; Ali H.R.; Microwave synthesis of 2,3-disubstituted-5-methyl-1,3-imidazolidines-4-one bearing benzothiazole moiety and elementarily assessment of their antibacterial action. J Phys Conf Ser 2018,1032,012058 [DOI: 10.1088/1742-6596/1032/1/012058]
34. Sharma P.C.; Padwal S.; Saini A.; Bansal K.; Synthesis, characterization and antimicrobial evaluation of benzimidazole clubbed benzothiazole derivatives. Chem Biol Lett 2017,4,63-68
35. Catalano A.; Carocci A.; Defrenza I.; Muraglia M.; Carrieri A.; Van Bambeke F.; Rosato A.; Corbo F.; Franchini C.; 2-Aminobenzothiazole derivatives: Search for new antifungal agents. Eur J Med Chem 2013,64,357-364 [DOI: 10.1016/j.ejmech.2013.03.064]
36. Goya-Jorge E.; Abdmouleh F.; Carpio L.E.; Giner R.M.; Sylla-Iyarreta Veitía M.; Discovery of 2-aryl and 2-pyridinylbenzo-thiazoles endowed with antimicrobial and aryl hydrocarbon receptor agonistic activities. Eur J Pharm Sci 2020,151,105386 [DOI: 10.1016/j.ejps.2020.105386]
37. Bandyopadhyay P.; Sathe M.; Ponmariappan S.; Sharma A.; Sharma P.; Srivastava A.K.; Kaushik M.P.; Exploration of in vitro time point quantitative evaluation of newly synthesized benzimidazole and benzothiazole derivatives as potential antibacterial agents. Bioorg Med Chem Lett 2011,21(24),7306-7309 [DOI: 10.1016/j.bmcl.2011.10.034]
38. Bait S.; Shinde S.; Adivarekar R.; Sekar N.; A study on multifunctional protein fibre with UV protection, moth repellency and antibacterial properties using ESIPT core containing benzimidazole and benzothiazole based functional acid azo dyes. J Indian Chem Soc 2021,98(12),100236 [DOI: 10.1016/j.jics.2021.100236]
39. Wang Y.; Zhou R.; Sun N.; He M.; Wu Y.; Xue W.; Synthesis and antibacterial activity of novel 1,4‐pentadien‐3‐one derivatives bearing a benzothiazole moiety. J Heterocycl Chem 2022,59(3),533-542 [DOI: 10.1002/jhet.4399]
40. Morsy M.A.; Ali E.M.; Kandeel M.; Venugopala K.N.; Nair A.B.; Greish K.; El-Daly M.; Screening and molecular docking of novel benzothiazole derivatives as potential antimicrobial agents. Antibiotics (Basel) 2020,9(5),221 [DOI: 10.3390/antibiotics9050221]
41. Kousaxidis A.; Kovacikova L.; Nicolaou I.; Stefek M.; Geronikaki A.; Non-acidic bifunctional benzothiazole-based thiazolidinones with antimicrobial and aldose reductase inhibitory activity as a promising therapeutic strategy for sepsis. Med Chem Res 2021,30(10),1837-1848 [DOI: 10.1007/s00044-021-02778-7]
42. Lipinski C.A.; Lead- and drug-like compounds: the rule-of-five revolution. Drug Discov Today Technol 2004,1(4),337-341 [DOI: 10.1016/j.ddtec.2004.11.007]
43. Chazin E.L.; Terra L.; Moor L.; Sanches P.; Pinto L.; Martins T.; de Souza M.; Gomes C.; Montenegro R.; Novais J.; 1, 3-benzoxathiol-2-one and 1, 3-benzothiazole compounds as potential anticancer and antimicrobial agents. Rev. Virtual Quím 2020,12,1586-1598 [DOI: 10.21577/1984-6835.20200125]
44. Pawar S.J.; Kale A.; Zori P.; Dorugade R.; Synthesis, molecular docking and antimicrobial evaluation of some benzothiazoles. Res Square 2021,2021,1-26
45. Maliyappa M.R.; Keshavayya J.; Nazrulla M.A.; Sudhanva M.S.; Rangappa S.; Six-substituted benzothiazole based dispersed azo dyes having antipyrine moiety: synthesis, characterization, DFT, antimicrobial, anticancer and molecular docking studies. J Iran Chem Soc 2022 [DOI: 10.1007/s13738-022-02569-w]
46. Khalil M.; Khalal Q.; Synthesis and characterization of new compounds derived from 2-hydrazinobenzothiazole and evaluated their antibacterial activity. 2021,012007
47. Saraswat P.; Jeyabalan G.; Hassan M.Z.; Ahsan M.J.; Design, synthesis and biological evaluation of benzothiazole-thiophene hybrids: A new class of potent antimicrobial agents. Antiinfect Agents 2018,16(1),57-63 [DOI: 10.2174/2211352515666171124155327]
48. Malunavar S.S.; Prabhala P.; Sutar S.M.; Kapavarapu R.; Mittal M.K.; Kalkhambkar R.G.; Molecular modeling and in vitro antimicrobial evaluation of some 2-aryl-benzoxazoles/benzothiazole analogues containing alkyl, alkenyl and alkynyl linkages. Chem Data Collect 2022,39,100876 [DOI: 10.1016/j.cdc.2022.100876]
49. Gilani S.J.; Nagarajan K.; Dixit S.P.; Taleuzzaman M.; Khan S.A.; Benzothiazole incorporated thiazolidin-4-ones and azetidin-2-ones derivatives: Synthesis and in vitro antimicrobial evaluation. Arab J Chem 2016,9,S1523-S1531 [DOI: 10.1016/j.arabjc.2012.04.004]
50. Maddili S.K.; Li Z.Z.; Kannekanti V.K.; Bheemanaboina R.R.Y.; Tuniki B.; Tangadanchu V.K.R.; Zhou C.H.; Azoalkyl ether imidazo[2,1-b]benzothiazoles as potentially antimicrobial agents with novel structural skeleton. Bioorg Med Chem Lett 2018,28(14),2426-2431 [DOI: 10.1016/j.bmcl.2018.06.016]
51. Mohamed K.S.; Elbialy E.E.; Fadda A.A.; Synthesis of novel heterocycles comprising benzothiazole moiety and their antimicrobial evaluations. Polycycl Aromat Compd 2021,2021,2014535 [DOI: 10.1080/10406638.2021.2014535]
52. Aa F.; Soliman N.N.; Fekri A.; Convenient route synthesis of some new benzothiazole derivatives and their pharmacological screening as antimicrobial agents. Ann Adv Chem 2017,1(1),032-046 [DOI: 10.29328/journal.aac.1001004]
53. Bondock S.; Khalifa W.; Fadda A.A.; Synthesis and antimicrobial evaluation of some new thiazole, thiazolidinone and thiazoline derivatives starting from 1-chloro-3,4-dihydronaphthalene-2-carbox-aldehyde. Eur J Med Chem 2007,42(7),948-954 [DOI: 10.1016/j.ejmech.2006.12.025]
54. Ouyang L.; Huang Y.; Zhao Y.; He G.; Xie Y.; Liu J.; He J.; Liu B.; Wei Y.; Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol and benzoxazol-2-amine derivatives. Bioorg Med Chem Lett 2012,22(9),3044-3049 [DOI: 10.1016/j.bmcl.2012.03.079]
55. Seenaiah D.; Reddy P.R.; Reddy G.M.; Padmaja A.; Padmavathi V.; Siva krishna N.; Synthesis, antimicrobial and cytotoxic activities of pyrimidinyl benzoxazole, benzothiazole and benzimidazole. Eur J Med Chem 2014,77,1-7 [DOI: 10.1016/j.ejmech.2014.02.050]
56. Zhang J.; Wei C.; Li S.; Hu D.; Song B.; Discovery of novel bis-sulfoxide derivatives bearing acylhydrazone and benzothiazole moieties as potential antibacterial agents. Pestic Biochem Physiol 2020,167,104605 [DOI: 10.1016/j.pestbp.2020.104605]
57. Stella A.; Segers K.; De Jonghe S.; Vanderhoydonck B.; Rozenski J.; Anné J.; Herdewijn P.; Synthesis and antibacterial evaluation of a novel series of 2-(1,2-dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles. Chem Biodivers 2011,8(2),253-265 [DOI: 10.1002/cbdv.201000241]
58. Catalano A.; Rosato A.; Salvagno L.; Iacopetta D.; Ceramella J.; Fracchiolla G.; Sinicropi M.S.; Franchini C.; Benzothiazole-containing analogues of triclocarban with potent antibacterial activity. Antibiotics (Basel) 2021,10(7),803 [DOI: 10.3390/antibiotics10070803]
59. Nehra N.; Tittal R.K.; Ghule V.D.; 1,2,3-Triazoles of 8-Hydroxyquinoline and HBT: Synthesis and studies (DNA binding, antimicrobial, molecular docking, ADME, and DFT). ACS Omega 2021,6(41),27089-27100 [DOI: 10.1021/acsomega.1c03668]
60. Zhang N.; Song D.; Chen W.; Zhang S.; Zhang P.; Zhang N.; Ma S.; Modification of 5-methylphenanthridium from benzothiazoles to indoles as potent FtsZ inhibitors: Broadening the antibacterial spectrum toward vancomycin-resistant enterococci. Eur J Med Chem 2021,224,113723 [DOI: 10.1016/j.ejmech.2021.113723]
61. Chaithanya M.s.; Nagendrappa G.; Vaidya V.P.; Rudraswamy M.S.; Synthesis, antibacterial, antifungal and antiinflammatory activities of 4-aryl-2-(4-chlorophenyl)-4H-pyrimido-[2,1-b][1,3]-benzothiazoles. Pharm Lett 2013,5,94-99
62. Sai Priya D.; Kini S.G.; Bhatt V.G.; Rathi E.; Muralidharan A.; Koteshwara A.; Novel schiff’s bases of substituted 2-amino benzothiazoles: Design, synthesis and antimicrobial activity. Indian Drugs 2018,55(4),18-26 [DOI: 10.53879/id.55.04.11219]
63. Naaz F.; Srivastava R.; Singh A.; Singh N.; Verma R.; Singh V.K.; Singh R.K.; Molecular modeling, synthesis, antibacterial and cytotoxicity evaluation of sulfonamide derivatives of benzimidazole, indazole, benzothiazole and thiazole. Bioorg Med Chem 2018,26(12),3414-3428 [DOI: 10.1016/j.bmc.2018.05.015]
64. Kumar P.; Bhatia R.; Khanna R.; Dalal A.; Kumar D.; Surain P.; Kamboj R.C.; Synthesis of some benzothiazoles by developing a new protocol using urea nitrate as a catalyst and their antimicrobial activities. J Sulfur Chem 2017,38,1334781 [DOI: 10.1080/17415993.2017.1334781]
65. Rezki N.; Aouad M.R.; Green ultrasound-assisted three-component click synthesis of novel 1 H -1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation. Acta Pharm 2017,67(3),309-324 [DOI: 10.1515/acph-2017-0024]
66. Wiegand I.; Hilpert K.; Hancock R.E.W.; Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc 2008,3(2),163-175 [DOI: 10.1038/nprot.2007.521]
67. Varaldo P.E.; Antimicrobial resistance and susceptibility testing: an evergreen topic. J Antimicrob Chemother 2002,50(1),dkf093 [DOI: 10.1093/jac/dkf093]
68. Zablotskaya A.; Segal I.; Geronikaki A.; Eremkina T.; Belyakov S.; Petrova M.; Shestakova I.; Zvejniece L.; Nikolajeva V.; Synthesis, physicochemical characterization, cytotoxicity, antimicrobial, anti-inflammatory and psychotropic activity of new N-[1,3-(benzo)thiazol-2-yl]-ω-[3,4-dihydroisoquinolin-2(1H)-yl]alkanamides. Eur J Med Chem 2013,70,846-856 [DOI: 10.1016/j.ejmech.2013.10.008]
69. Padalkar V.S.; Borse B.N.; Gupta V.D.; Phatangare K.R.; Patil V.S.; Sekar N.; Synthesis and antimicrobial activities of novel 2-[substituted-1 H -pyrazol-4-yl] benzothiazoles, benzoxazoles, and benzimidazoles. J Heterocycl Chem 2016,53(5),1347-1355 [DOI: 10.1002/jhet.1506]
70. Geesi M.H.; Ouerghi O.; Dehbi O.; Riadi Y.; Metal-doped TiO2 nanocatalysts in an MX2/urea mixture for the synthesis of benzothiazoles bearing substituted pyrrolidin-2-ones: Enhanced catalytic performance and antibacterial activity. J Environ Chem Eng 2021,9(4),105344 [DOI: 10.1016/j.jece.2021.105344]
71. Palkar M.; Noolvi M.; Sankangoud R.; Maddi V.; Gadad A.; Nargund L.V.G.; Synthesis and antibacterial activity of a novel series of 2,3-diaryl-substituted-imidazo(2,1-b)-benzothiazole derivatives. Arch Pharm (Weinheim) 2010,343(6),353-359 [DOI: 10.1002/ardp.200900260]
72. Wang X.; Chen J.; Wang W.; Jaunarajs A.; Wang X.; Tryptoline-based benzothiazoles re-sensitize MRSA to β-lactam antibiotics. Bioorg Med Chem 2019,27(21),115095 [DOI: 10.1016/j.bmc.2019.115095]
73. Gurram S.R.; Azam M.A.; Design, Synthesis, antibacterial evaluation and molecular docking studies of some newer baenzothiazole containing aryl and alkaryl hydrazides. Chem Biodivers 2021,18(7),e2100117 [DOI: 10.1002/cbdv.202100117]
74. Kumbhare R.M.; Dadmal T.L.; Pamanji R.; Kosurkar U.B.; Velatooru L.R.; Appalanaidu K.; Khageswara Rao Y.; Venkateswara Rao J.; Synthesis of novel fluoro 1,2,3-triazole tagged amino bis(benzothiazole) derivatives, their antimicrobial and anticancer activity. Med Chem Res 2014,23(10),4404-4413 [DOI: 10.1007/s00044-014-1006-0]
75. Kumbhare M.R.; Nagragu C.; Synthesis and study of the antimicrobial activity of novel tricyclic 2 hpyrimido [2, 1-b] benzothiazoles. Lett Drug Des Discov 2011,8,633-639 [DOI: 10.2174/157018011796235211]
76. Er M.; Özer A.; Direkel Ş.; Karakurt T.; Tahtaci H.; Novel substituted benzothiazole and Imidazo[2,1-b][1,3,4]Thiadiazole derivatives: Synthesis, characterization, molecular docking study, and investigation of their in vitro antileishmanial and antibacterial activities. J Mol Struct 2019,1194,284-296 [DOI: 10.1016/j.molstruc.2019.05.104]
77. Trott O.; Olson A.J.; AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem 2010,31(2),455-461 [PMID: 19499576]
78. DS Discovery Studio Modeling Environment Release 45 BIOVIA2015
79. Racané L.; Ptiček L.; Fajdetić G.; Tralić-Kulenović V.; Klobučar M.; Kraljević Pavelić S. ; Perić M.; Paljetak H.Č; Verbanac D.; Starčević K.; Green synthesis and biological evaluation of 6-substituted-2-(2-hydroxy/methoxy phenyl)benzothiazole derivatives as potential antioxidant, antibacterial and antitumor agents. Bioorg Chem 2020,95,103537 [DOI: 10.1016/j.bioorg.2019.103537]
80. Zha L.; Xie Y.; Wu C.; Lei M.; Lu X.; Tang W.; Zhang J.; Novel benzothiazole-urea hybrids: Design, synthesis and biological activity as potent anti-bacterial agents against MRSA. Eur J Med Chem 2022,236,114333 [DOI: 10.1016/j.ejmech.2022.114333]
81. Bax B.D.; Chan P.F.; Eggleston D.S.; Fosberry A.; Gentry D.R.; Gorrec F.; Giordano I.; Hann M.M.; Hennessy A.; Hibbs M.; Huang J.; Jones E.; Jones J.; Brown K.K.; Lewis C.J.; May E.W.; Saunders M.R.; Singh O.; Spitzfaden C.E.; Shen C.; Shillings A.; Theobald A.J.; Wohlkonig A.; Pearson N.D.; Gwynn M.N.; Type IIA topoisomerase inhibition by a new class of antibacterial agents. Nature 2010,466(7309),935-940 [DOI: 10.1038/nature09197]
82. Kyhoiesh H.A.K.; Al-Adilee K.J.; Synthesis, spectral characterization and biological activities of Ag(I), Pt(IV) and Au(III) complexes with novel azo dye ligand (N, N, O) derived from 2-amino-6-methoxy benzothiazole. Chem Zvesti 2022,76(5),2777-2810 [DOI: 10.1007/s11696-022-02072-9]
83. Mishra A.; Batar A.; Kumar R.; Khandelwal A.; Lama P.; Chhabra M.; Metre R.K.; Assembly of Di-, tetra- and hexanuclear organostannoxanes using hemi labile intramolecular n→sn coordination: synthesis, structure, DFT and antibacterial studies. Polyhedron 2021,209,115487 [DOI: 10.1016/j.poly.2021.115487]
84. Singh G.; Diksha; Mohit; Suman; Shilpy; Devi, A.; Gupta, S.; Yadav, R.; Sehgal, R. Benzothiazole tethered triazole based potential antibacterial agent as a selective fluorometric probe for the detection of Al3+ ions and phenylalanine. J Mol Struct 2022,1262,132967 [DOI: 10.1016/j.molstruc.2022.132967]
85. Mishra N.; Kumar K.; Pandey H.; Raj Anand S.; Yadav R.; Prakash Srivastava S.; Pandey R.; Synthesis, characterization, optical and anti-bacterial properties of benzothiazole Schiff bases and their lanthanide (III) complexes. J Saudi Chem Soc 2020,24(12),925-933 [DOI: 10.1016/j.jscs.2020.09.009]
86. Ibrahim S.; Gavisiddegowda P.; Deepakumari H.N.; Kollur S.P.; Naik N.; Newly synthesized benzothiazole derived ligand and its Co (III) and Ru (III) complexes as biological potent molecules: Chemical preparation, structure, antimicrobial, in vitro and in vivo cytotoxicity studies. Biointerface Res Appl Chem 2022,12(6),7817-7844
87. Jawoor S.S.; Patil S.A.; Toragalmath S.S.; Synthesis and characterization of heteroleptic Schiff base transition metal complexes: a study of anticancer, antimicrobial, DNA cleavage and anti-TB activity. J Coord Chem 2018,71(2),271-283 [DOI: 10.1080/00958972.2017.1421951]
88. Rambabu A.; Pradeep Kumar M.; Tejaswi S.; Vamsikrishna N.; Shivaraj, DNA interaction, antimicrobial studies of newly synthesized copper (II) complexes with 2-amino-6-(trifluoromethoxy)] benzothiazole Schiff base ligands. J Photochem Photobiol B 2016,165,147-156 [DOI: 10.1016/j.jphotobiol.2016.10.027]
89. Meghdadi S.; Amirnasr M.; Mirhashemi A.; Amiri A.; Synthesis, characterization and X-ray crystal structure of copper(I) complexes of the 2-(2-quinolyl)benzothiazole ligand. Electrochemical and antibacterial studies. Polyhedron 2015,97,234-239 [DOI: 10.1016/j.poly.2015.05.026]
90. Chakraborty I.; Pinto M.; Stenger-Smith J.; Martinez-Gonzalez J.; Mascharak P.K.; Synthesis, structures and antibacterial properties of Cu(II) and Ag(I) complexes derived from 2,6-bis(benzothiazole)-pyridine. Polyhedron 2019,172,1-7 [DOI: 10.1016/j.poly.2019.02.001]
91. Jung W.K.; Koo H.C.; Kim K.W.; Shin S.; Kim S.H.; Park Y.H.; Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Appl Environ Microbiol 2008,74(7),2171-2178 [DOI: 10.1128/AEM.02001-07]
92. Rao N.N.; kishan E.; Gopichand K.; Nagaraju R.; Ganai A.M.; Rao P.V.; Design, synthesis, spectral characterization, DNA binding, photo cleavage and antibacterial studies of transition metal complexes of benzothiazole Schiff base. Chem Data Collect 2020,27,100368 [DOI: 10.1016/j.cdc.2020.100368]
93. Stenger-Smith J.; Chakraborty I.; Sameera W.M.C.; Mascharak P.K.; Antimicrobial silver (I) complexes derived from aryl-benzothiazoles as turn-on sensors: Syntheses, properties and density functional studies. Inorg Chim Acta 2018,471,326-335 [DOI: 10.1016/j.ica.2017.11.022]
94. Stenger-Smith J.; Chakraborty I.; Mascharak P.K.; Cationic Au(I) complexes with aryl-benzothiazoles and their antibacterial activity. J Inorg Biochem 2018,185,80-85 [DOI: 10.1016/j.jinorgbio.2018.05.003]
95. Pal N.; Arya A.K.; An efficient and facile synthesis of Zn(II) complexes with 2-substituted benzothiazoles and glycine- and alanine-based ligands having antifungal and antibacterial activities. Res Chem Intermed 2013,39(2),553-560 [DOI: 10.1007/s11164-012-0578-x]
96. Ahlawat A.; Khatkar P.; Singh V.; Asija S.; Diorganotin(IV) complexes of Schiff bases derived from salicylaldehyde and 2-amino-6-substituted benzothiazoles: synthesis, spectral studies, in vitro antimicrobial evaluation and QSAR studies. Res Chem Intermed 2018,44(7),4415-4435 [DOI: 10.1007/s11164-018-3395-z]
97. Devi J.; Devi S.; Kumar A.; Synthesis, spectral, and in vitro antimicrobial studies of organosilicon(IV) complexes with Schiff bases derived from dehydroacetic acid. Monatsh Chem 2016,147(12),2195-2207 [DOI: 10.1007/s00706-016-1720-z]
98. Dias L.C.; de Lima G.M.; Takahashi J.A.; Ardisson J.D.; New di- and triorganotin(IV) carboxylates derived from a Schiff base: synthesis, characterization and in vitro antimicrobial activities. Appl Organomet Chem 2015,29(5),305-313 [DOI: 10.1002/aoc.3292]
99. Czympiel L.; Lekeu J.M.; Hegemann C.; Mathur S.; Oxidative halogenation of Sn(II)heteroaryl alkenolates: Formation of unusual trans -dihalo Sn(IV) complexes. Inorg Chim Acta 2017,455,197-203 [DOI: 10.1016/j.ica.2016.10.023]

Grants

1. 631/Deanship of Scientific Research of King Faisal University, Saudi Arabia

MeSH Term

Chemicals