OpenLB
Open Library of Bioscience
Advanced Search
Antibiotics (Basel, Switzerland)
Jan 06, 2023;12 (1):

Surveillance in a Neonatal Intensive Care Unit Allowed the Isolation of a Strain of VIM-Producing .

Cristina Merla, Irene Mileto, Stefano Gaiarsa, Cristian Achille, Stefano Ghirardello, Marta Corbella, Fausto Baldanti, Patrizia Cambieri
Author Information
  1. Cristina Merla: UOC Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy. ORCID
  2. Irene Mileto: UOC Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
  3. Stefano Gaiarsa: UOC Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
  4. Cristian Achille: Neonatologia e Terapia Intensiva Neonatale, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
  5. Stefano Ghirardello: Neonatologia e Terapia Intensiva Neonatale, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
  6. Marta Corbella: UOC Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy. ORCID
  7. Fausto Baldanti: UOC Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
  8. Patrizia Cambieri: UOC Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
PMID: 36671299 DOI: 10.3390/antibiotics12010098

Abstract

Here, we describe the isolation of a strain of the genus encoding a VIM carbapenemase, the first to our knowledge. The strain, isolated from a rectal swab of a 10-day-old newborn admitted to a neonatal intensive care unit (NICU), was identified through whole-genome sequencing analyses as . The strain harbored the carbapenemases gene . The prompt application of contact measures and the isolation of the newborn prevented the dissemination of VIM-producing and of the plasmid carrying the VIM-1 gene to other newborns.

Keywords

Pantoea brenneri VIM neonatal intensive care unit newborn screening for carbapenemase-resistant Enterobacterales verona integron ��-lactamase

References

  1. Med Princ Pract. 2008;17(6):500-3 [PMID: 18836282]
  2. J Antimicrob Chemother. 2010 Aug;65(8):1608-14 [PMID: 20513703]
  3. Braz J Infect Dis. 2007 Apr;11(2):281-4 [PMID: 17625778]
  4. Pediatrics. 2018 Dec;142(6): [PMID: 30455342]
  5. J Clin Microbiol. 2007 Jun;45(6):1989-92 [PMID: 17442803]
  6. Cureus. 2021 Feb 3;13(2):e13103 [PMID: 33643749]
  7. J Hosp Infect. 2005 Nov;61(3):213-8 [PMID: 16213372]
  8. Antimicrob Agents Chemother. 2014 Jul;58(7):3895-903 [PMID: 24777092]
  9. J Med Case Rep. 2019 Feb 13;13(1):33 [PMID: 30755259]
  10. Antimicrob Agents Chemother. 2020 Mar 24;64(4): [PMID: 32015041]
  11. Microb Drug Resist. 2014 Apr;20(2):131-7 [PMID: 24171449]
  12. J Infect Public Health. 2018 May - Jun;11(3):304-309 [PMID: 28780309]
  13. Int J Syst Evol Microbiol. 2010 Oct;60(Pt 10):2430-2440 [PMID: 19946052]
  14. Clin Microbiol Infect. 2012 May;18(5):413-31 [PMID: 22507109]
  15. Microb Drug Resist. 2022 Apr;28(4):408-412 [PMID: 35349384]
  16. Healthcare (Basel). 2021 Jun 07;9(6): [PMID: 34200170]
  17. Ann Agric Environ Med. 2016 Jun 2;23(2):197-205 [PMID: 27294620]
  18. J Med Case Rep. 2015 Sep 04;9:188 [PMID: 26341678]
  19. Infect Control Hosp Epidemiol. 2017 Mar;38(3):314-319 [PMID: 27919308]
  20. Infez Med. 2014 Jun;22(2):152-5 [PMID: 24955805]
  21. BMC Infect Dis. 2021 Oct 27;21(1):1108 [PMID: 34706677]
  22. Microbiome. 2018 Nov 13;6(1):204 [PMID: 30424821]
  23. J Antimicrob Chemother. 2020 Dec 1;75(12):3491-3500 [PMID: 32780112]
  24. New Microbiol. 2009 Jan;32(1):119-23 [PMID: 19382678]
  25. Microb Pathog. 2022 Feb;163:105385 [PMID: 34995748]
  26. Clin Microbiol Rev. 2012 Oct;25(4):682-707 [PMID: 23034326]
Case Reports
Article has an altmetric score of 1

Word Cloud

Created with Highcharts 10.0.0strainnewbornisolationVIMneonatalintensivecareunitgenedescribegenusencodingcarbapenemasefirstknowledgeisolatedrectalswab10-day-oldadmittedNICUidentifiedwhole-genomesequencinganalysesharboredcarbapenemasespromptapplicationcontactmeasurespreventeddisseminationVIM-producingplasmidcarryingVIM-1newbornsSurveillanceNeonatalIntensiveCareUnitAllowedIsolationStrainVIM-ProducingPantoeabrenneriscreeningcarbapenemase-resistantEnterobacteralesveronaintegron��-lactamase

Similar Articles

Cited By