OpenLB
Open Library of Bioscience
Advanced Search
Molecules (Basel, Switzerland)
Jan 10, 2023;28 (2):

Triterpenoid and Steroid Content of Lipophilic Extracts of Selected Medicinal Plants of the Mediterranean Region.

Leila Gadouche, Abdulwadood Shakir Mahmood Alsoufi, Dominika Pacholska, Anna Skotarek, Cezary Pączkowski, Anna Szakiel
Author Information
  1. Leila Gadouche: Department of Biology and Physiology of Organisms, Faculty of Biological Sciences, University of Sciences and Technology Houari Boumediene, P.O. Box 32, El Alia, Bab Ezzouar, Algiers 16111, Algeria. ORCID
  2. Abdulwadood Shakir Mahmood Alsoufi: Department of Biology, College of Science, University of Tikrit, P.O. Box 42, Tikrit 34001, Iraq.
  3. Dominika Pacholska: Department of Plant Biochemistry, Faculty of Biology, University of Warsaw, 1 Miecznikowa Street, 02-096 Warsaw, Poland.
  4. Anna Skotarek: Department of Plant Biochemistry, Faculty of Biology, University of Warsaw, 1 Miecznikowa Street, 02-096 Warsaw, Poland.
  5. Cezary Pączkowski: Department of Plant Biochemistry, Faculty of Biology, University of Warsaw, 1 Miecznikowa Street, 02-096 Warsaw, Poland.
  6. Anna Szakiel: Department of Plant Biochemistry, Faculty of Biology, University of Warsaw, 1 Miecznikowa Street, 02-096 Warsaw, Poland. ORCID
PMID: 36677757 DOI: 10.3390/molecules28020697

Abstract

The available phytochemical characteristics of the medicinal plants and derived herbal material often lack data concerning the content of steroids (including phytosterols) and triterpenoids, that can be responsible for various beneficial properties and therapeutic effects, either directly, or as a result of synergistic action with other bioactive constituents. The aim of the present work was the analysis of the content of these compounds in herbal material (leaves, aerial parts) derived from selected medicinal plants (, , , , , ), widely used in folk medicine in the Mediterranean region. Results obtained by gas chromatography-mass spectrometry (GC-MS)-targeted profiling revealed the diversity in the profiles and contents of steroids and triterpenoids in the analyzed plant material, ranging from 5.7% d.w. in to 0.1% in . The obtained results supplement the existing phytochemical data of the investigated medicinal plants, pointing to the aerial parts and leaves as valuable resources of phytosterols and bioactive triterpenoids.

Keywords

Cistus ladanifer Cistus monspeliensis Erica arborea Globularia alypum Pistacia lentiscus Rhamnus alaternus steroids triterpenoids

References

  1. Molecules. 2016 Jul 21;21(7): [PMID: 27455211]
  2. Nat Prod Res. 2008;22(16):1385-92 [PMID: 19023799]
  3. Biochem Res Int. 2021 Dec 7;2021:6669877 [PMID: 34917418]
  4. Int J Mol Sci. 2020 Dec 21;21(24): [PMID: 33371323]
  5. Afr J Tradit Complement Altern Med. 2016 Aug 12;13(5):1-6 [PMID: 28487887]
  6. Phytochemistry. 2021 Feb;182:112596 [PMID: 33321444]
  7. Int J Mol Sci. 2022 Oct 12;23(20): [PMID: 36293029]
  8. J Mol Graph Model. 2021 Jun;105:107900 [PMID: 33780786]
  9. Cancer Lett. 2012 Jul 28;320(2):158-70 [PMID: 22406826]
  10. PLoS One. 2021 Dec 28;16(12):e0260956 [PMID: 34962953]
  11. Evid Based Complement Alternat Med. 2015;2015:854373 [PMID: 26347794]
  12. Compr Rev Food Sci Food Saf. 2020 Jul;19(4):1243-1267 [PMID: 33337101]
  13. Med Res Rev. 2018 May;38(3):951-976 [PMID: 29350407]
  14. Molecules. 2015 Nov 19;20(11):20614-41 [PMID: 26610440]
  15. Curr Med Chem. 2013;20(7):908-31 [PMID: 23210780]
  16. Lipids Health Dis. 2018 Apr 16;17(1):82 [PMID: 29661192]
  17. Molecules. 2019 Oct 23;24(21): [PMID: 31652872]
  18. Molecules. 2022 Jan 14;27(2): [PMID: 35056839]
  19. Molecules. 2010 Oct 11;15(10):6956-73 [PMID: 20938406]
  20. Molecules. 2021 Feb 02;26(3): [PMID: 33540622]
  21. Nat Prod Res. 2013 Aug;27(15):1404-7 [PMID: 23148482]
  22. J Complement Integr Med. 2017 Sep 13;15(1): [PMID: 28915116]
  23. J Nutr Sci Vitaminol (Tokyo). 2003 Aug;49(4):277-80 [PMID: 14598915]
  24. Molecules. 2011 Dec 19;16(12):10592-603 [PMID: 22183884]
  25. Plants (Basel). 2021 Sep 30;10(10): [PMID: 34685879]
  26. Chem Biodivers. 2022 Mar;19(3):e202101012 [PMID: 35170187]
  27. BMC Complement Med Ther. 2022 Jul 20;22(1):194 [PMID: 35858857]
  28. Front Physiol. 2018 Apr 24;9:412 [PMID: 29765328]
  29. Molecules. 2016 Sep 23;21(10): [PMID: 27669205]
  30. Molecules. 2019 Nov 28;24(23): [PMID: 31795252]
  31. Antioxidants (Basel). 2023 Dec 14;12(12): [PMID: 38136233]
  32. Plants (Basel). 2021 Jun 15;10(6): [PMID: 34203720]
  33. Plants (Basel). 2022 Nov 18;11(22): [PMID: 36432894]
  34. J Pharmacopuncture. 2019 Jun;22(2):55-67 [PMID: 31338244]
  35. J Agric Food Chem. 2012 May 16;60(19):4994-5002 [PMID: 22490120]
  36. Molecules. 2022 Jan 27;27(3): [PMID: 35164112]
  37. Front Pharmacol. 2020 Jan 09;10:1480 [PMID: 31998121]
  38. Antioxidants (Basel). 2021 Nov 05;10(11): [PMID: 34829643]
  39. J Agric Food Chem. 2012 Dec 5;60(48):11839-49 [PMID: 23157739]
  40. Front Chem. 2014 Jun 11;2:35 [PMID: 24967222]
  41. Int J Mol Sci. 2022 May 18;23(10): [PMID: 35628449]
  42. Pharmaceuticals (Basel). 2022 Apr 21;15(5): [PMID: 35631332]
  43. BMC Complement Med Ther. 2020 Oct 14;20(1):306 [PMID: 33054740]
  44. Biomed Res Int. 2017;2017:2789482 [PMID: 28116307]
  45. ScientificWorldJournal. 2013 Dec 15;2013:219815 [PMID: 24453812]
  46. Food Sci Nutr. 2021 Jul 23;9(9):5070-5082 [PMID: 34532016]

MeSH Term

Plants, Medicinal
Triterpenes
Phytochemicals
Plant Extracts
Phytosterols

Chemicals

Triterpenes
Phytochemicals
Plant Extracts
Phytosterols
Journal Article

Word Cloud

Created with Highcharts 10.0.0triterpenoidsmedicinalplantsmaterialsteroidsphytochemicalderivedherbaldatacontentphytosterolsbioactiveleavesaerialpartsMediterraneanobtainedCistusavailablecharacteristicsoftenlackconcerningincludingcanresponsiblevariousbeneficialpropertiestherapeuticeffectseitherdirectlyresultsynergisticactionconstituentsaimpresentworkanalysiscompoundsselectedwidelyusedfolkmedicineregionResultsgaschromatography-massspectrometryGC-MS-targetedprofilingrevealeddiversityprofilescontentsanalyzedplantranging57%dw01%resultssupplementexistinginvestigatedpointingvaluableresourcesTriterpenoidSteroidContentLipophilicExtractsSelectedMedicinalPlantsRegionladanifermonspeliensisEricaarboreaGlobulariaalypumPistacialentiscusRhamnusalaternus

Similar Articles

Cited By