Combination venetoclax and olverembatinib (HQP1351) as a successful therapeutic strategy for relapsed/refractory (R/R) mixed-phenotype blast phase of chronic myeloid leukemia.
Tongtong Zhang, Haixia Zhou, Mingzhu Xu, Chongsheng Qian, Aining Sun, Depei Wu, Shengli Xue
Author Information
- Tongtong Zhang: Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China. ORCID
- Haixia Zhou: Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China.
- Mingzhu Xu: Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China.
- Chongsheng Qian: Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China.
- Aining Sun: Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China.
- Depei Wu: Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China.
- Shengli Xue: Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China. slxue@suda.edu.cn.
No abstract text available.
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- 81970138/National Natural Science Foundation of China
- 81900130/National Natural Science Foundation of China
- 2020ZKMB05/Translational Research Grant of NCRCH
- BE2021649/Social Development Project of the Science and Technology Department of Jiangsu
- GSWS2019007/Gusu Key Medical Talent Program
Humans
Blast Crisis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia, Myeloid
Bridged Bicyclo Compounds, Heterocyclic
Antineoplastic Combined Chemotherapy Protocols
Leukemia, Myeloid, Acute
venetoclax
olverembatinib
Bridged Bicyclo Compounds, Heterocyclic