OpenLB
Open Library of Bioscience
Advanced Search
Infection and drug resistance
2023;16 1345-1355.

Antibacterial Mechanism of Against Methicillin Resistant .

Xin Liu, Lili An, Yonghui Zhou, Wei Peng, Cong Huang
Author Information
  1. Xin Liu: College of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang City, People's Republic of China.
  2. Lili An: Dermatology Department, the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang City, People's Republic of China.
  3. Yonghui Zhou: College of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang City, People's Republic of China.
  4. Wei Peng: College of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang City, People's Republic of China.
  5. Cong Huang: College of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang City, People's Republic of China.
PMID: 36925724 DOI: 10.2147/IDR.S398227

Abstract

Purpose: has become one of the most common causes of septicemia. Meanwhile, has acquired resistance to many antibiotics. Among these, methicillin-resistant (MRSE) were frequently isolated. Similar to methicillin resistant (MRSA), they also exhibited multi-resistance, which presented a danger to human health. as traditional Chinese medicine had strong antibacterial activity against MRSE. However, the mechanism of against MRSE is not clear.
Methods: Here, the morphology of cell wall and cell membrane, production of β-lactamase and PBP2, energy metabolism, antioxidant system were systematically studied.
Results: The data showed that damaged the cell wall and membrane. In addition, β-lactamase, energy metabolism and antioxidant system were involved in mechanisms of against MRSE.
Conclusion: These observations provided new understanding of against MRSE to control MRSE infections.

Keywords

Patrinia scabiosifolia antioxidant system energy metabolism methicillin-resistantStaphylococcus epidermidis β-lactamase

References

  1. Food Chem. 2021 Jul 15;350:129218 [PMID: 33621817]
  2. Infect Drug Resist. 2022 Mar 06;15:883-893 [PMID: 35281570]
  3. J Antibiot (Tokyo). 2017 Jul 26;: [PMID: 28743973]
  4. World J Microbiol Biotechnol. 2019 Mar 21;35(4):57 [PMID: 30900046]
  5. Int J Microbiol. 2013;2013:760969 [PMID: 24222768]
  6. Food Chem. 2020 Mar 30;309:125692 [PMID: 31670119]
  7. ACS Appl Bio Mater. 2021 Apr 19;4(4):3124-3132 [PMID: 35014400]
  8. Fitoterapia. 2005 Jan;76(1):1-25 [PMID: 15664457]
  9. J Ethnopharmacol. 2020 May 10;253:112652 [PMID: 32035880]
  10. Int J Mol Sci. 2021 Jun 08;22(12): [PMID: 34201389]
  11. mSphere. 2015 Nov 04;1(1): [PMID: 27303682]
  12. Microbiol Immunol. 2003;47(3):207-12 [PMID: 12725290]
  13. Clin Microbiol Rev. 2014 Oct;27(4):870-926 [PMID: 25278577]
  14. J Ethnopharmacol. 2010 Jul 6;130(1):107-15 [PMID: 20435121]
  15. Front Cell Infect Microbiol. 2017 Mar 21;7:90 [PMID: 28377905]
  16. J Glob Antimicrob Resist. 2020 Sep;22:195-201 [PMID: 32097759]
  17. Front Chem. 2019 Jan 10;6:657 [PMID: 30687698]
  18. Sci Rep. 2019 Dec 6;9(1):18533 [PMID: 31811214]
  19. Biosci Rep. 2019 Oct 30;39(10): [PMID: 31548363]
  20. ChemMedChem. 2018 Oct 22;13(20):2240-2248 [PMID: 30193012]
  21. Front Immunol. 2020 Oct 15;11:534099 [PMID: 33178181]
Journal Article
Article has an altmetric score of 1

Word Cloud

Created with Highcharts 10.0.0MRSEcellβ-lactamaseenergymetabolismantioxidantsystemwallmembranePurpose:becomeonecommoncausessepticemiaMeanwhileacquiredresistancemanyantibioticsAmongmethicillin-resistantfrequentlyisolatedSimilarmethicillinresistantMRSAalsoexhibitedmulti-resistancepresenteddangerhumanhealthtraditionalChinesemedicinestrongantibacterialactivityHowevermechanismclearMethods:morphologyproductionPBP2systematicallystudiedResults:datashoweddamagedadditioninvolvedmechanismsConclusion:observationsprovidednewunderstandingcontrolinfectionsAntibacterialMechanismMethicillinResistantPatriniascabiosifoliamethicillin-resistantStaphylococcusepidermidis

Similar Articles

Cited By