Impact of (recurrent) bacterial vaginosis on quality of life and the need for accessible alternative treatments.

Karen Chow, Darcy Wooten, Sindhuja Annepally, Leah Burke, Rina Edi, Sheldon R Morris
Author Information
  1. Karen Chow: Department of Medicine, University of California San Diego, San Diego, CA, USA.
  2. Darcy Wooten: Department of Medicine, University of California San Diego, San Diego, CA, USA.
  3. Sindhuja Annepally: Department of Medicine, University of California San Diego, San Diego, CA, USA.
  4. Leah Burke: Department of Medicine, University of California San Diego, San Diego, CA, USA. lbburke@health.ucsd.edu.
  5. Rina Edi: Department of Medicine, University of California San Diego, San Diego, CA, USA.
  6. Sheldon R Morris: Department of Medicine, University of California San Diego, San Diego, CA, USA.

Abstract

BACKGROUND: Bacterial vaginosis (BV) is one of the most common vaginal dysbiosis in women aged 15-44 years old.
METHODS: We administered a cross-sectional, single timepoint survey to women ages 18 years or older and who have had bacterial vaginosis (BV). Women completed an anonymous online survey evaluating the impact of BV on their quality of life, how effective different types of treatments were and the amount of self-diagnosed vs. provider diagnosed BV episodes they had.
RESULTS: 62 participants completed the anonymous online survey. With a self-reported median number of BV episodes in the past year was 4 (IQR 1-7). Among these women 69.8% reported BV had a negative impact on their sexual health, 67.7% on their physical health, 74.6% on their mental health. More than half of the respondents had used probiotics with oral Lactobacillus sp. (53.2%), mainly by oral route, and over a third had used vaginal boric acid (37.1%). Most women were unaware of Lactobacillus crispatus. Lactobacillus probiotics were more likely to be tried by women who were negatively impacted by BV for overall quality of life (p���=���0.033), sexual health (p���=���0.002), and mental health (p���=���0.006) while boric acid use was more likely to be used by women who were negatively impacted by BV for their sexual health (p���=���0.008).
CONCLUSIONS: BV is associated with negative quality of life and the women most impacted are seeking alternative treatments such as probiotics (Lactobacillus) and boric acid. There needs to be improvements in BV treatment that include alternative therapy options that have demonstrated efficacy with standardized composition, formulation and dosage.

Keywords

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MeSH Term

Female
Humans
Adolescent
Young Adult
Adult
Vaginosis, Bacterial
Quality of Life
Cross-Sectional Studies
Vagina
Lactobacillus
Probiotics

Chemicals

boric acid

Word Cloud

Created with Highcharts 10.0.0BVwomenhealthvaginosisLactobacillusqualitylifeacidp���=���0surveybacterialtreatmentssexualusedprobioticsboricimpactedalternativeBacterialvaginalcompletedanonymousonlineimpactepisodesnegativementalorallikelynegativelyBACKGROUND:onecommondysbiosisaged15-44 yearsoldMETHODS:administeredcross-sectionalsingletimepointages18 yearsolderWomenevaluatingeffectivedifferenttypesamountself-diagnosedvsproviderdiagnosedhadRESULTS:62participantsself-reportedmediannumberpastyear4IQR1-7Among698%reported677%physical746%halfrespondentssp532%mainlyroutethird371%unawarecrispatustriedoverall033002006use008CONCLUSIONS:associatedseekingneedsimprovementstreatmentincludetherapyoptionsdemonstratedefficacystandardizedcompositionformulationdosageImpactrecurrentneedaccessibleAlternativetherapiesBoricRecurrent

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