Meta-Transcriptomic Analysis Reveals Novel RNA Viruses in .
Fan Zhang, Zhihao Ren, Xiaomeng Guo, Yiting Wang, Fanzeng Meng, Weifeng Shi, Xinping Wang, Xuan Dong
Author Information
Fan Zhang: College of Marine Science and Biological Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Zhihao Ren: Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. ORCID
Xiaomeng Guo: Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Laboratory for Marine Fisheries Science and Food Production Processes, Pilot National Laboratory for Marine Science and Technology (Qingdao), Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture and Rural Affairs, Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Qingdao 266071, China.
Yiting Wang: Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Laboratory for Marine Fisheries Science and Food Production Processes, Pilot National Laboratory for Marine Science and Technology (Qingdao), Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture and Rural Affairs, Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Qingdao 266071, China.
Fanzeng Meng: Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Laboratory for Marine Fisheries Science and Food Production Processes, Pilot National Laboratory for Marine Science and Technology (Qingdao), Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture and Rural Affairs, Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Qingdao 266071, China.
Weifeng Shi: Shanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. ORCID
Xinping Wang: College of Marine Science and Biological Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Xuan Dong: College of Marine Science and Biological Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Lined seahorse, , is an important aquatic animal due to its medicinal and ornamental purposes. However, our understanding of the viral spectrum in is still limited. Here, we studied the viruses in using meta-transcriptomic sequencing. A total of 213,770,166 reads were generated and assembled de novo into 539 virus-associated contigs. Three novel RNA viruses from the , , and families were finally identified. In addition, we identified a strain of nervous necrosis virus from . In particular, the unhealthy group showed a higher viral diversity and abundance than the normal group. These results revealed the diversity and cross-species transmission of viruses in and highlighted the threat of viral infections to .
