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04 06, 2023;9 (1): 17.

Chikungunya fever.

Koen Bartholomeeusen, Matthieu Daniel, Desiree A LaBeaud, Philippe Gasque, Rosanna W Peeling, Kathryn E Stephenson, Lisa F P Ng, Kevin K Ari��n
Author Information
  1. Koen Bartholomeeusen: Virology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
  2. Matthieu Daniel: Unit�� de Recherche en Pharmaco-Immunologie (UR-EPI), Universit�� et CHU de La R��union, Saint-Denis, France.
  3. Desiree A LaBeaud: Department of Pediatrics, Division of Infectious Disease, Stanford University School of Medicine, Stanford, CA, USA.
  4. Philippe Gasque: Unit�� de Recherche en Pharmaco-Immunologie (UR-EPI), Universit�� et CHU de La R��union, Saint-Denis, France.
  5. Rosanna W Peeling: Clinical Research Department, London School of Hygiene and Tropical Medicine, London, UK.
  6. Kathryn E Stephenson: Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. ORCID
  7. Lisa F P Ng: A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research, Singapore, Singapore. ORCID
  8. Kevin K Ari��n: Virology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium. karien@itg.be. ORCID
PMID: 37024497 DOI: 10.1038/s41572-023-00429-2

Abstract

Chikungunya virus is widespread throughout the tropics, where it causes recurrent outbreaks of Chikungunya fever. In recent years, outbreaks have afflicted populations in East and Central Africa, South America and Southeast Asia. The virus is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Chikungunya fever is characterized by severe arthralgia and myalgia that can persist for years and have considerable detrimental effects on health, quality of life and economic productivity. The effects of climate change as well as increased globalization of commerce and travel have led to growth of the habitat of Aedes mosquitoes. As a result, increasing numbers of people will be at risk of Chikungunya fever in the coming years. In the absence of specific antiviral treatments and with vaccines still in development, surveillance and vector control are essential to suppress re-emergence and epidemics.

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Grants

  1. R01 AI102918/NIAID NIH HHS

MeSH Term

Animals
Humans
Chikungunya Fever
Quality of Life
Mosquito Vectors
Chikungunya virus
Aedes
Journal Article Review
Article has an altmetric score of 132

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