Weighted Average Ensemble Deep Learning Model for Stratification of Brain Tumor in MRI Images.

Vatsala Anand, Sheifali Gupta, Deepali Gupta, Yonis Gulzar, Qin Xin, Sapna Juneja, Asadullah Shah, Asadullah Shaikh
Author Information
  1. Vatsala Anand: Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura 140401, Punjab, India.
  2. Sheifali Gupta: Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura 140401, Punjab, India. ORCID
  3. Deepali Gupta: Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura 140401, Punjab, India. ORCID
  4. Yonis Gulzar: Department of Management Information Systems, College of Business Administration, King Faisal University, Al-Ahsa 31982, Saudi Arabia. ORCID
  5. Qin Xin: Faculty of Science and Technology, University of the Faroe Islands, Vestarabryggja 15, FO 100 Torshavn, Faroe Islands, Denmark. ORCID
  6. Sapna Juneja: Kulliyyah of Information and Communication Technology, International Islamic University Malaysia, Gombak 53100, Selangor, Malaysia. ORCID
  7. Asadullah Shah: Kulliyyah of Information and Communication Technology, International Islamic University Malaysia, Gombak 53100, Selangor, Malaysia. ORCID
  8. Asadullah Shaikh: Department of Information Systems, College of Computer Science and Information Systems, Najran University, Najran 55461, Saudi Arabia. ORCID

Abstract

Brain tumor diagnosis at an early stage can improve the chances of successful treatment and better patient outcomes. In the biomedical industry, non-invasive diagnostic procedures, such as magnetic resonance imaging (MRI), can be used to diagnose brain tumors. Deep learning, a type of artificial intelligence, can analyze MRI images in a matter of seconds, reducing the time it takes for diagnosis and potentially improving patient outcomes. Furthermore, an ensemble model can help increase the accuracy of classification by combining the strengths of multiple models and compensating for their individual weaknesses. Therefore, in this research, a weighted average ensemble deep learning model is proposed for the classification of brain tumors. For the weighted ensemble classification model, three different feature spaces are taken from the transfer learning VGG19 model, Convolution Neural Network (CNN) model without augmentation, and CNN model with augmentation. These three feature spaces are ensembled with the best combination of weights, i.e., weight1, weight2, and weight3 by using grid search. The dataset used for simulation is taken from The Cancer Genome Atlas (TCGA), having a lower-grade glioma collection with 3929 MRI images of 110 patients. The ensemble model helps reduce overfitting by combining multiple models that have learned different aspects of the data. The proposed ensemble model outperforms the three individual models for detecting brain tumors in terms of accuracy, precision, and F1-score. Therefore, the proposed model can act as a second opinion tool for radiologists to diagnose the tumor from MRI images of the brain.

Keywords

References

  1. Diagnostics (Basel). 2020 Aug 06;10(8): [PMID: 32781795]
  2. Front Comput Neurosci. 2022 Nov 01;16:1000435 [PMID: 36387304]
  3. IEEE Trans Pattern Anal Mach Intell. 2022 Dec;44(12):9904-9917 [PMID: 34855586]
  4. Front Neurosci. 2020 Jan 24;13:1449 [PMID: 32038146]
  5. J Neurooncol. 2017 May;133(1):27-35 [PMID: 28470431]
  6. Comput Biol Med. 2019 Jun;109:218-225 [PMID: 31078126]
  7. Comput Biol Med. 2022 Oct;149:106079 [PMID: 36108413]
  8. Comput Biol Med. 2022 Jul;146:105657 [PMID: 35672170]
  9. Proc Eur Signal Process Conf EUSIPCO. 2019 Sep;2019: [PMID: 35495099]
  10. Front Oncol. 2022 Jun 29;12:932496 [PMID: 35847931]
  11. Magn Reson Imaging. 2022 Feb;86:28-36 [PMID: 34715290]
  12. Comput Struct Biotechnol J. 2022 Aug 27;20:4733-4745 [PMID: 36147663]

Grants

  1. GRANT2,792/Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University

Word Cloud

Created with Highcharts 10.0.0modelcanMRIbrainensembletumortumorslearningimagesclassificationmodelsweightedproposedthreeCNNaugmentationBraindiagnosispatientoutcomesbiomedicaluseddiagnoseDeepaccuracycombiningmultipleindividualThereforeaveragedifferentfeaturespacestakenConvolutionNeuralNetworkensembleddataearlystageimprovechancessuccessfultreatmentbetterindustrynon-invasivediagnosticproceduresmagneticresonanceimagingtypeartificialintelligenceanalyzemattersecondsreducingtimetakespotentiallyimprovingFurthermorehelpincreasestrengthscompensatingweaknessesresearchdeeptransferVGG19withoutbestcombinationweightsieweight1weight2weight3usinggridsearchdatasetsimulationCancerGenomeAtlasTCGAlower-gradegliomacollection3929110patientshelpsreduceoverfittinglearnedaspectsoutperformsdetectingtermsprecisionF1-scoreactsecondopiniontoolradiologistsWeightedAverageEnsembleLearningModelStratificationTumorImages

Similar Articles

Cited By