A study of post-traumatic stress disorder in schizophrenic patients 35 years after experiencing the Tangshan earthquake.

Wenyou Ma, Rong Lei, Yan Sun, Xiaoliang Liang, Shun Zhang, Changqi Wang, Ying Tang, Gang Wang, Hebin Li, Zhenjian Yu
Author Information
  1. Wenyou Ma: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China. ORCID
  2. Rong Lei: Department of Children and Adolescents, Second People's Hospital of Huizhou, Huizhou, China.
  3. Yan Sun: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.
  4. Xiaoliang Liang: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.
  5. Shun Zhang: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.
  6. Changqi Wang: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.
  7. Ying Tang: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.
  8. Gang Wang: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.
  9. Hebin Li: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.
  10. Zhenjian Yu: Department of Clinical Psychology, Kailuan Mental Health Center Affiliated to North China University of Science and Technology, Tangshan, Hebei, China.

Abstract

BACKGROUND: This study aimed to investigate the relationship between Dissociative experiences, post-traumatic stress disorder (PTSD), and psychiatric symptoms exhibited by schizophrenic patients 35 years after the Tangshan earthquake.
METHODS: Seventy-one schizophrenic patients who had experienced the Tangshan earthquake were selected and evaluated by the Post-traumatic Dissociative Experience Questionnaire (PDEQ), thPTSD Checklist-Civilian Version (PCL-C), and the Positive and Negative Symptom Scale (PANSS).
RESULTS: The score of Group B (re-experiencing symptoms) in PCL-C was significantly positively correlated with age and significantly negatively correlated with the course of schizophrenia. Both gender and marriage were significantly positively correlated with the score of PCL-C Group D (irritability symptoms caused by hyperarousal). The PDEQ score was negatively correlated with thecourse of schizophrenia and positively correlated with the presence of sleep difficulties. Significant differences were found between the PCL-C scores of the positive and negative symptoms of the three core symptom groups; the positive rate of Group B was significantly higher than that of Group D, and the positive rate of Group C was significantly higher than that of Group D. The PCL-C total score was positively correlated with the negative symptom factor score of PANSS; Group C's symptoms were significantly negativelycorrelated with the positive factor score of PNASS; andGroup D's' symptoms were significantly negatively correlated with the PANSS total score and the positive factor score.
CONCLUSION: When consiering patients with schizophrenia post the Tangshan earthquake, age, gender, and marital status were all positively correlated with PTSD. The course of schizophrenia was negatively associated with PTSD and Dissociative experiences. PTSD was positively correlated with the negative symptoms of schizophrenia and negatively correlated with the positive symptoms of schizophrenia. Thus, the conditions and symptoms of PTSD may interact with those of schizophrenia.

Keywords

References

  1. J Abnorm Psychol. 2003 Aug;112(3):415-23 [PMID: 12943020]
  2. Psychopharmacology (Berl). 1993;112(1 Suppl):S16-34 [PMID: 7831438]
  3. Biomedicines. 2022 Apr 20;10(5): [PMID: 35625690]
  4. World J Biol Psychiatry. 2017 Apr;18(3):162-214 [PMID: 27419272]
  5. Encephale. 2015 Sep;41(4):346-54 [PMID: 25238908]
  6. Lancet Psychiatry. 2015 Mar;2(3):258-270 [PMID: 26359903]
  7. NPJ Schizophr. 2021 Apr 26;7(1):22 [PMID: 33903594]
  8. Sleep. 2020 Jul 13;43(7): [PMID: 31971594]
  9. Brain Sci. 2021 Sep 30;11(10): [PMID: 34679364]
  10. J Clin Psychiatry. 2000;61 Suppl 7:44-51 [PMID: 10795609]
  11. Am J Psychiatry. 1997 Aug;154(8):1114-9 [PMID: 9247398]
  12. Psychiatr Genet. 2020 Feb;30(1):1-9 [PMID: 31764709]
  13. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:361-379 [PMID: 30342071]
  14. Brain Behav. 2023 May;13(5):e2963 [PMID: 37067013]
  15. J Gen Intern Med. 2020 Feb;35(2):505-513 [PMID: 31792872]
  16. J Affect Disord. 2020 Mar 1;264:407-413 [PMID: 31791678]
  17. Arch Gen Psychiatry. 1995 Dec;52(12):1048-60 [PMID: 7492257]
  18. J Consult Clin Psychol. 1998 Jun;66(3):493-9 [PMID: 9642887]
  19. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Apr;5(4):381-391 [PMID: 32033924]
  20. Schizophr Res. 2002 Jan 1;53(1-2):123-43 [PMID: 11728845]
  21. PLoS One. 2015 Mar 27;10(3):e0121480 [PMID: 25815720]
  22. Psychopathology. 2010;43(1):33-40 [PMID: 19893342]
  23. J Nerv Ment Dis. 2006 Nov;194(11):853-8 [PMID: 17102710]
  24. Exp Neurol. 2020 Aug;330:113331 [PMID: 32343956]
  25. Occup Med (Lond). 2016 Oct;66(7):514-21 [PMID: 27036149]
  26. Eur Arch Psychiatry Clin Neurosci. 2007 Jun;257(4):191-6 [PMID: 17464547]
  27. Am J Psychiatry. 1989 Dec;146(12):1530-40 [PMID: 2686473]
  28. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jan 10;88:265-275 [PMID: 30092241]
  29. Eur Psychiatry. 2005 Mar;20(2):145-51 [PMID: 15797699]
  30. Asian J Psychiatr. 2013 Feb;6(1):3-21 [PMID: 23380312]
  31. Psychiatr Serv. 2003 Apr;54(4):523-8 [PMID: 12663840]
  32. Front Psychiatry. 2020 Jan 10;10:890 [PMID: 31998147]
  33. J Anxiety Disord. 2015 Apr;31:90-7 [PMID: 25768398]
  34. J Trauma Stress. 1998 Oct;11(4):645-64 [PMID: 9870219]
  35. Psychol Med. 2021 Apr;51(6):976-988 [PMID: 31931901]
  36. J Affect Disord. 2015 Jul 15;180:116-21 [PMID: 25898331]
  37. Neuroscience. 2019 Jan 1;396:36-45 [PMID: 30452973]
  38. Presse Med. 2018 May;47(5):423-430 [PMID: 29580906]
  39. Neuropsychopharmacology. 2016 Jan;41(1):297-319 [PMID: 26321314]

MeSH Term

Humans
Earthquakes
Stress Disorders, Post-Traumatic
Surveys and Questionnaires
Survivors

Word Cloud

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