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May 25, 2023;12 (11):

Metagenomics: An Effective Approach for Exploring Microbial Diversity and Functions.

Nguyen Nhat Nam, Hoang Dang Khoa Do, Kieu The Loan Trinh, Nae Yoon Lee
Author Information
  1. Nguyen Nhat Nam: Biotechnology Center, School of Agriculture and Aquaculture, Tra Vinh University, Tra Vinh City 87000, Vietnam. ORCID
  2. Hoang Dang Khoa Do: NTT Hi-Tech Institute, Nguyen Tat Thanh University, Ward 13, District 04, Ho Chi Minh City 72820, Vietnam.
  3. Kieu The Loan Trinh: Department of BioNano Technology, Gachon University 1342 Seongnam-daero, Sujeong-gu, Seongnam-si 13120, Republic of Korea.
  4. Nae Yoon Lee: Department of BioNano Technology, Gachon University 1342 Seongnam-daero, Sujeong-gu, Seongnam-si 13120, Republic of Korea. ORCID
PMID: 37297385 DOI: 10.3390/foods12112140

Abstract

Various fields have been identified in the "omics" era, such as genomics, proteomics, transcriptomics, metabolomics, phenomics, and metagenomics. Among these, metagenomics has enabled a significant increase in discoveries related to the microbial world. Newly discovered microbiomes in different ecologies provide meaningful information on the diversity and functions of microorganisms on the Earth. Therefore, the results of metagenomic studies have enabled new microbe-based applications in human health, agriculture, and the food industry, among others. This review summarizes the fundamental procedures on recent advances in bioinformatic tools. It also explores up-to-date applications of metagenomics in human health, food study, plant research, environmental sciences, and other fields. Finally, metagenomics is a powerful tool for studying the microbial world, and it still has numerous applications that are currently hidden and awaiting discovery. Therefore, this review also discusses the future perspectives of metagenomics.

Keywords

food safety metagenomics microbial diversity next-generation sequencing

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Grants

  1. 2021R1A6A1A03038996/Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education
  2. 2020R1A6C101A184/Korea Basic Science Institute (National research Facilities and Equipment Center) grant funded by the Ministry of Education
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