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Iranian journal of microbiology
Jun, 2023;15 (3): 350-358.

Epidemiology of nosocomial and infections in a neonatal intensive care unit.

Fatemeh Nayeri, Hosein Dalili, Mamak Shariat, Nahid Farrokhzad, Kosar Abouhamzeh, Leyla Sahebi
Author Information
  1. Fatemeh Nayeri: Maternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
  2. Hosein Dalili: Breastfeeding Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
  3. Mamak Shariat: Maternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
  4. Nahid Farrokhzad: Maternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
  5. Kosar Abouhamzeh: Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
  6. Leyla Sahebi: Maternal-Fetal and Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
PMID: 37448676 DOI: 10.18502/ijm.v15i3.12895

Abstract

Background and Objectives: This study aimed to investigate epidemiology of and infections in neonatal intensive care unit (NICU) in a period of 8 years.
Materials and Methods: This retrospective cohort study was conducted on 46 cases of nosocomial infection by and 44 neonates with in NICU of Valiasr hospital, Iran.
Results: The trend of and infection were as follows: 1 and 7 in 2014, 11 and 7 in 2015, 20 and 11 in 2016, 1 and 4 in 2017, 4 and 6 in 2018, 4 and 4 in 2019, 0 and 1 in 2020, and 3 and 6 in 2021-March 2022 respectively. Mortality proportion (%) in neonates with and infection was at 8.3 and 32.1, respectively. There was a strong positive correlation between number of infected neonates in month and average of prescribed antibiotics before incidence of infection in every baby in that month. Fluconazole prescription before incidence of infection were associated with the infection in month too. Amikacin prescription had adjusted correlation on increasing of and infection in month.
Conclusion: It seems reducing of hospitalization duration and medication prescriptions management plays an important role in reducing of nosocomial infections.

Keywords

Acinetobacter baumannii Neonatal intensive care units Nosocomial infections Outbreak Staphylococcus epidermidis

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Journal Article
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