Ultra high-speed single-molecule fluorescence imaging.

Zengxin Huang, Pakorn Kanchanawong
Author Information
  1. Zengxin Huang: Mechanobiology Institute, National University of Singapore , Singapore, Republic of Singapore.
  2. Pakorn Kanchanawong: Mechanobiology Institute, National University of Singapore , Singapore, Republic of Singapore. ORCID

Abstract

In two articles in this issue, Fujiwara et al. developed an ultrasensitive high-speed camera capable of single-molecule fluorescence imaging at a microsecond timescale (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202110160). This major leap in detection speed enables the organization of plasma membrane and integrin-based adhesions to be probed in unprecedented detail (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202110162).

References

  1. Nat Methods. 2014 Mar;11(3):253-66 [PMID: 24577276]
  2. Nat Protoc. 2022 Oct;17(10):2275-2306 [PMID: 35896742]
  3. Annu Rev Cell Dev Biol. 2012;28:215-50 [PMID: 22905956]
  4. Nat Rev Mol Cell Biol. 2023 Feb;24(2):142-161 [PMID: 36168065]
  5. Nat Chem Biol. 2014 Jul;10(7):524-32 [PMID: 24937070]

MeSH Term

Cell Membrane
Optical Imaging
Integrins

Chemicals

Integrins

Word Cloud

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