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Patient preference and adherence
2023;17 1657-1670.

The Mediating Effect of Self-Efficacy on the Relationship Between Medication Literacy and Medication Adherence Among Patients with Type 2 Diabetes.

Haoqi Liu, Ziqiang Yao, Shuangjiao Shi, Feng Zheng, Xia Li, Zhuqing Zhong
Author Information
  1. Haoqi Liu: Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, People's Republic of China. ORCID
  2. Ziqiang Yao: Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, People's Republic of China.
  3. Shuangjiao Shi: Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, People's Republic of China.
  4. Feng Zheng: Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, People's Republic of China.
  5. Xia Li: Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, People's Republic of China.
  6. Zhuqing Zhong: Nursing Department, The Third Xiangya Hospital, Central South University, Changsha, People's Republic of China. ORCID
PMID: 37465055 DOI: 10.2147/PPA.S413385

Abstract

Background: Patients with type 2 diabetes have poor medication adherence. Medication literacy is one of the influencing factors of medication adherence among patients with type 2 diabetes. However, the mechanism by which medication literacy affects medication adherence among patients with type 2 diabetes is unclear. The aim of this study was to verify the mediating role of self-efficacy in the relationship between medication literacy and medication adherence.
Methods: A total of 402 patients with type 2 diabetes were enrolled in this study. The Chinese versions of the Medication Literacy Scale, the Self-Efficacy for Appropriate Medication Use Scale and the Morisky Medication Adherence Scale-8 were used in the survey. Pearson correlation analysis was used to find correlations among medication literacy, self-efficacy and medication adherence. The PROCESS macro (Version 4.1) with Model 4 for SPSS was used to verify the mediating role of self-efficacy.
Results: Twenty-four percent of the participants had poor medication adherence. Self-efficacy and medication literacy (r=0.499, p < 0.01) and medication adherence (r=0.499, p < 0.01) were significantly and positively correlated. Self-efficacy partially mediated the relationship between medication knowledge and medication adherence among patients with type 2 diabetes, accounting for 36.7% of the total effect.
Conclusion: Self-efficacy had a partial mediating effect on the relationship between medication literacy and medication adherence among patients with type 2 diabetes. Self-efficacy should be improved through effective measures to increase patients' confidence in adherence to antihyperglycemic drugs.

Keywords

mediating effect medication adherence medication literacy self-efficacy type 2 diabetes

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Journal Article
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