Prevailing practice patterns in keratoconus among Indian ophthalmologists.

Rashmi Deshmukh, Alok Kumar Shrivastava, Pravin Krishna Vaddavalli
Author Information
  1. Rashmi Deshmukh: Cataract and Refractive Services, LV Prasad Eye Institute, Hyderabad, Telangana, India.
  2. Alok Kumar Shrivastava: Cataract and Refractive Services, LV Prasad Eye Institute, Hyderabad, Telangana; Sri Innovation and Research Foundation, Ghaziabad, Uttar Pradesh, India.
  3. Pravin Krishna Vaddavalli: Cataract and Refractive Services, LV Prasad Eye Institute, Hyderabad, Telangana; Shantilal Sanghvi Eye Institute, Hyderabad, Telangana, India.

Abstract

Objective: The past few years have seen a rapid advancement in the management of keratoconus (KC). However, there is no prescribed standard of care for the management of KC. This study evaluated the prevailing practice patterns among Indian ophthalmologists in the diagnosis and treatment of KC via an online survey.
Methods: This was a survey-based cross-sectional study in which a questionnaire (Supplement 1) was created. Questions pertaining to the practicing experience, setting of practice, and training background were asked in addition to the investigations done and decision making in KC management. Responses were collected via Survey Monkey (Survey Monkey, Palo Alto, California, USA) and statistical analysis performed using R software (4.1.3).
Results: The survey was answered by 273 ophthalmologists. Pentacam was the most used topographer (195 users), followed by Orbscan (41 users), Sirius (34 users), and Galilei (3 users). The lowest limit of pachymetry for performing collagen crosslinking (CXL) was 400μ for most practitioners. More than half the respondents (50.55%) did not perform photorefractive keratectomy (PRK) or intracorneal ring segment (ICRS) implantation in a suitable patient. Accelerated 10-minute protocol (9 mW/cm for 10 minutes) was the most commonly (54.21%) used for CXL, followed by Dresden protocol (3 mW/cm for 30 minutes) (36.63%). When a patient was unsuitable for CXL, 55.31% surgeons advise contact lens (CL) trial, 35.16% surgeons advise keratoplasty, 26.74% surgeons perform stromal augmentation, and 7.69% surgeons advise spectacle correction. Corneal scar was the most common indication (49.45%) for performing keratoplasty.
Conclusion: Topography remains the most used diagnostic modality for initial diagnosis. Optical coherence tomography and epithelial mapping are increasingly being used for early diagnosis of KC. Not all ophthalmologists were comfortable performing ICRS or PRK. When patients are unsuitable for CXL, CL trial remains the most frequently advised option followed by keratoplasty.

Keywords

References

  1. Am J Ophthalmol. 2008 Dec;146(6):905-12.e1 [PMID: 18723138]
  2. Eye Vis (Lond). 2018 Sep 12;5:24 [PMID: 30238016]
  3. Curr Opin Allergy Clin Immunol. 2019 Oct;19(5):526-534 [PMID: 31343437]
  4. Cornea. 2016 May;35(5):673-8 [PMID: 26989959]
  5. Indian J Ophthalmol. 2020 Dec;68(12):2757-2772 [PMID: 33229651]
  6. Br J Ophthalmol. 2023 Feb;107(2):176-180 [PMID: 34479856]
  7. J Cataract Refract Surg. 2005 Jan;31(1):205-20 [PMID: 15721715]
  8. Cornea. 2017 May;36(5):523-529 [PMID: 28230557]
  9. Eye (Lond). 2021 Jan;35(1):173-187 [PMID: 32678352]
  10. Indian J Ophthalmol. 2019 Jan;67(1):8-15 [PMID: 30574883]
  11. Indian J Ophthalmol. 2017 Apr;65(4):305-310 [PMID: 28513495]
  12. Eur J Ophthalmol. 2020 Jul;30(4):635-642 [PMID: 30857417]
  13. Cureus. 2022 Nov 29;14(11):e32030 [PMID: 36600839]
  14. Cornea. 2011 Aug;30(8):917-9 [PMID: 21389853]
  15. Am J Ophthalmol. 2017 Mar;175:122-128 [PMID: 27993593]
  16. J Cataract Refract Surg. 2015 Apr;41(4):812-20 [PMID: 25840306]
  17. J Cataract Refract Surg. 2014 Feb;40(2):269-75 [PMID: 24368115]
  18. Curr Opin Ophthalmol. 1997 Aug;8(4):8-24 [PMID: 10170448]
  19. Int Ophthalmol. 2018 Dec;38(6):2519-2526 [PMID: 29086323]
  20. Cont Lens Anterior Eye. 2019 Dec;42(6):662-665 [PMID: 31060894]
  21. Transl Vis Sci Technol. 2021 Apr 29;10(5):13 [PMID: 34967830]
  22. Cornea. 2020 Feb;39(2):215-221 [PMID: 31478950]
  23. J Cataract Refract Surg. 2020 Feb;46(2):276-286 [PMID: 32126042]
  24. Graefes Arch Clin Exp Ophthalmol. 2018 Aug;256(8):1363-1384 [PMID: 29623463]
  25. Am J Ophthalmol. 2015 Aug;160(2):243-9 [PMID: 26008626]
  26. Curr Opin Ophthalmol. 2006 Aug;17(4):356-60 [PMID: 16900027]
  27. Surv Ophthalmol. 2017 Nov - Dec;62(6):770-783 [PMID: 28688894]
  28. Annu Rev Vis Sci. 2020 Sep 15;6:25-46 [PMID: 32320633]
  29. J Refract Surg. 2019 Nov 1;35(11):740-747 [PMID: 31710377]
  30. Indian J Ophthalmol. 2015 Jan;63(1):46-53 [PMID: 25686063]
  31. Invest Ophthalmol Vis Sci. 2014 Jul 29;55(8):5263-8 [PMID: 25074774]
  32. Eye (Lond). 2020 Dec;34(12):2175-2196 [PMID: 32641797]

MeSH Term

Humans
Asian People
Contact Lenses
Cross-Sectional Studies
Keratoconus
Ophthalmologists
India
Practice Patterns, Physicians'

Word Cloud

Created with Highcharts 10.0.0KCpracticeophthalmologistsusedusersCXLsurgeonsmanagementpatternsdiagnosissurvey3followedperformingadvisekeratoplastykeratoconusstudyamongIndianvia1SurveyMonkeyperformPRKICRSpatientprotocolmW/cmminutesunsuitableCLtrialremainsObjective:pastyearsseenrapidadvancementHoweverprescribedstandardcareevaluatedprevailingtreatmentonlineMethods:survey-basedcross-sectionalquestionnaireSupplementcreatedQuestionspertainingpracticingexperiencesettingtrainingbackgroundaskedadditioninvestigationsdonedecisionmakingResponsescollectedPaloAltoCaliforniaUSAstatisticalanalysisperformedusingRsoftware4Results:answered273Pentacamtopographer195Orbscan41Sirius34Galileilowestlimitpachymetrycollagencrosslinking400μpractitionershalfrespondents5055%photorefractivekeratectomyintracornealringsegmentimplantationsuitableAccelerated10-minute910commonly5421%Dresden303663%5531%contactlens3516%2674%stromalaugmentation769%spectaclecorrectionCornealscarcommonindication4945%Conclusion:TopographydiagnosticmodalityinitialOpticalcoherencetomographyepithelialmappingincreasinglyearlycomfortablepatientsfrequentlyadvisedoptionPrevailingKeratoconus

Similar Articles

Cited By