Increase in bloodstream infections caused by 1 group A correlates with emergence of toxigenic M1, Belgium, May 2022 to August 2023.

Juan Pablo Rodriguez-Ruiz, Qiang Lin, Christine Lammens, Pierre R Smeesters, Stefanie van Kleef-van Koeveringe, Veerle Matheeussen, Surbhi Malhotra-Kumar
Author Information
  1. Juan Pablo Rodriguez-Ruiz: Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Antwerp, Belgium.
  2. Qiang Lin: Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Antwerp, Belgium.
  3. Christine Lammens: Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Antwerp, Belgium.
  4. Pierre R Smeesters: National Reference Centre for invasive β-haemolytic streptococci, Belgium.
  5. Stefanie van Kleef-van Koeveringe: National Reference Centre for invasive β-haemolytic streptococci, Belgium.
  6. Veerle Matheeussen: Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Antwerp, Belgium.
  7. Surbhi Malhotra-Kumar: Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Antwerp, Belgium.

Abstract

Many European countries have recently reported upsurges in invasive group A (iGAS) infections, mainly caused by 1 , specifically the toxigenic M1 lineage. We present the epidemiology of 1 causing iGAS in Belgium during 2018-August 2023, and describe an emergence of the toxigenic M1 lineage in Belgium in mid-2022 that was observed as an increase in bloodstream infections caused by 1 that continued into 2023.

Keywords

References

  1. Clin Microbiol Infect. 2023 Jul;29(7):887-890 [PMID: 36925107]
  2. JAMA. 2023 May 23;329(20):1791-1792 [PMID: 37027150]
  3. Lancet Infect Dis. 2023 Feb;23(2):154-156 [PMID: 36634683]
  4. Curr Protoc Bioinformatics. 2020 Jun;70(1):e102 [PMID: 32559359]
  5. Microb Genom. 2023 Apr;9(4): [PMID: 37093716]
  6. Euro Surveill. 2023 Jan;28(1): [PMID: 36695450]
  7. iScience. 2020 Jan 24;23(1):100769 [PMID: 31887656]
  8. Open Forum Infect Dis. 2023 Apr 06;10(5):ofad188 [PMID: 37180594]
  9. Euro Surveill. 2023 Jun;28(26): [PMID: 37382884]
  10. Bioinformatics. 2014 Jul 15;30(14):2068-9 [PMID: 24642063]
  11. Pediatr Infect Dis J. 2023 Apr 1;42(4):e122-e124 [PMID: 36728741]
  12. Lancet Infect Dis. 2019 Nov;19(11):1209-1218 [PMID: 31519541]

MeSH Term

Humans
Belgium
Streptococcus pyogenes
Europe
Sepsis
Streptococcal Infections
United Kingdom

Word Cloud

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