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Oct, 2024;274 (7): 1651-1660.

Automatic sensory change processing in adults with attention deficit and hyperactivity disorder: a visual mismatch negativity study.

Chen Dang, Xiangsheng Luo, Yu Zhu, Bingkun Li, Yuan Feng, Chenyang Xu, Simin Kang, Gaohan Yin, Stuart J Johnstone, Yufeng Wang, Yan Song, Li Sun
Author Information
  1. Chen Dang: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  2. Xiangsheng Luo: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  3. Yu Zhu: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  4. Bingkun Li: State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing, China.
  5. Yuan Feng: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  6. Chenyang Xu: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  7. Simin Kang: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  8. Gaohan Yin: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  9. Stuart J Johnstone: School of Psychology, University of Wollongong, Wollongong, NSW, Australia.
  10. Yufeng Wang: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
  11. Yan Song: State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing, China. songyan@bnu.edu.cn.
  12. Li Sun: Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China. sunlioh@bjmu.edu.cn. ORCID
PMID: 37831221 DOI: 10.1007/s00406-023-01695-7

Abstract

In addition to higher-order executive functions, underlying sensory processing ability is also thought to play an important role in Attention-Deficit/Hyperactivity Disorder (AD/HD). An event-related potential feature, the mismatch negativity, reflects the ability of automatic sensory change processing and may be correlated with AD/HD symptoms and executive functions. This study aims to investigate the characteristics of visual mismatch negativity (vMMN) in adults with AD/HD. Twenty eight adults with AD/HD and 31 healthy controls were included in this study. These two groups were matched in age, IQ and sex. In addition, both groups completed psychiatric evaluations, a visual ERP task used to elicit vMMN, and psychological measures about AD/HD symptoms and day-to-day executive functions. Compared to trols, the late vMMN (230-330 ms) was significantly reduced in the AD/HD group. Correlation analyses showed that late vMMN was correlated with executive functions but not AD/HD symptoms. However, further mediation analyses showed that different executive functions had mediated the relationships between late vMMN and AD/HD symptoms. Our findings indicate that the late vMMN, reflecting automatic sensory change processing ability, was impaired in adults with AD/HD. This impairment could have negative impact on AD/HD symptoms via affecting day-to-day executive functions.

Keywords

AD/HD Automatic sensory change processing Day-to-day executive functions Visual mismatch negativity

References

  1. Posner J, Polanczyk GV, Sonuga-Barke E (2020) Attention-deficit hyperactivity disorder. Lancet (London, England) 395(10222):450���462. https://doi.org/10.1016/S0140-6736(19)33004-1 [DOI: 10.1016/S0140-6736(19)33004-1]
  2. Anbarasan D, Kitchin M, Adler LA (2020) Screening for Adult ADHD. Curr Psychiatry Rep. 22(12):72. https://doi.org/10.1007/s11920-020-01194-9 [DOI: 10.1007/s11920-020-01194-9]
  3. Barkley RA (1997) Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull 121(1):65���94. https://doi.org/10.1037/0033-2909.121.1.65 [DOI: 10.1037/0033-2909.121.1.65]
  4. Sonuga-Barke EJS, Houlberg K, Hall M (1994) When is ���Impulsiveness��� not Impulsive? The case of Hyperactive Children���s Cognitive Style. J Child Psychol Psychiatry 35:1247���1253. https://doi.org/10.1111/j.1469-7610.1994.tb01232.x [DOI: 10.1111/j.1469-7610.1994.tb01232.x]
  5. Sergeant JA, Geurts H, Huijbregts S, Scheres A, Oosterlaan J (2003) The top and the bottom of ADHD: a neuropsychological perspective. Neurosci Biobehav Rev 27(7):583���592. https://doi.org/10.1016/j.neubiorev.2003.08.004 [DOI: 10.1016/j.neubiorev.2003.08.004]
  6. Butzbach M, Fuermaier ABM, Aschenbrenner S, Weisbrod M, Tucha L, Tucha O (2019) Basic processes as foundations of cognitive impairment in adult ADHD. J Neural Transm 126(10):1347���1362. https://doi.org/10.1007/s00702-019-02049-1 [DOI: 10.1007/s00702-019-02049-1]
  7. Cortese S, Kelly C, Chabernaud C, Proal E, Di Martino A, Milham MP, Castellanos FX (2012) Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studies. Am J Psychiatry 169(10):1038���1055. https://doi.org/10.1176/appi.ajp.2012.11101521 [DOI: 10.1176/appi.ajp.2012.11101521]
  8. Luo X, Guo J, Li D, Liu L, Chen Y, Zhu Y, Johnstone SJ, Wang Y, Song Y, Sun L (2021) Atypical developmental trajectories of early perception among school-age children with attention deficit hyperactivity disorder during a visual search task. Child Dev 92(6):e1186���e1197. https://doi.org/10.1111/cdev.13604 [DOI: 10.1111/cdev.13604]
  9. Miller LJ, Nielsen DM, Schoen SA (2012) Attention deficithyperactivity disorder and sensory modulation disorder: a comparison ofbehavior and physiology. Res Dev Disabil 33(3):804���818. https://doi.org/10.1016/j.ridd.2011.12.005 [DOI: 10.1016/j.ridd.2011.12.005]
  10. L��zaro A, Berruezo P (2009) La pir��mide del desarrollo humano. Rev Iberoamericana de Psicomotricidad T��cn Corp 34(9):2
  11. Fuermaier ABM, H��pen P, De Vries SM et al (2018) Perception in attention deficit hyperactivity disorder. ADHD Atten Def Hyp Disord 10:21���47. https://doi.org/10.1007/s12402-017-0230-0 [DOI: 10.1007/s12402-017-0230-0]
  12. Bijlenga D, Tjon-Ka-Jie JYM, Schuijers F, Kooij JJS (2017) Atypical sensory profiles as core features of adult ADHD, irrespective of autistic symptoms. Eur Psychiatry 43:51���57. https://doi.org/10.1016/j.eurpsy.2017.02.481 [DOI: 10.1016/j.eurpsy.2017.02.481]
  13. Delgado-Lobete L, P��rtega-D��az S, Santos-Del-Riego S, Montes-Montes R (2020) Sensory processing patterns in developmental coordination disorder, attention deficit hyperactivity disorder and typical development. Res Dev Disabil 100:103608. https://doi.org/10.1016/j.ridd.2020.103608 [DOI: 10.1016/j.ridd.2020.103608]
  14. Dellapiazza F, Michelon C, Vernhet C, Muratori F, Blanc N, Picot MC, Baghdadli A, for ELENA study group, (2021) Sensory processing related to attention in children with ASD, ADHD, or typical development: results from the ELENA cohort. Eur Child Adolesc Psychiatry 30(2):283���291. https://doi.org/10.1007/s00787-020-01516-5 [DOI: 10.1007/s00787-020-01516-5]
  15. Kamath MS, Dahm CR, Tucker JR, Huang-Pollock CL, Etter NM, Neely KA (2020) Sensory profiles in adults with and without ADHD. Res Dev Disabil 104:103696. https://doi.org/10.1016/j.ridd.2020.103696 [DOI: 10.1016/j.ridd.2020.103696]
  16. Mimouni-Bloch A, Offek H, Rosenblum S, Posener I, Silman Z, Engel-Yeger B (2018) Association between sensory modulation and daily activity function of children with attention deficit/hyperactivity disorder andchildren with typical development. Res Dev Disabil 83:69���76. https://doi.org/10.1016/j.ridd.2018.08.002 [DOI: 10.1016/j.ridd.2018.08.002]
  17. Sabri M, Kareken DA, Dzemidzic M, Lowe MJ, Melara RD (2004) Neural correlates of auditory sensory memory and automatic change detection. Neuroimage 21(1):69���74. https://doi.org/10.1016/j.neuroimage.2003.08.033 [DOI: 10.1016/j.neuroimage.2003.08.033]
  18. File D, Sulykos I, Czigler I (2020) Automatic change detection and spatial attention: a visual mismatch negativity study. Eur J Neurosci 52(11):4423���4431. https://doi.org/10.1111/ejn.13945 [DOI: 10.1111/ejn.13945]
  19. Czigler I, Kojouharova P (2022) Visual Mismatch Negativity: AMini-Review of Non-pathological Studies With Special Populations and Stimuli. Front Hum Neurosci 15:781234. https://doi.org/10.3389/fnhum.2021.781234 [DOI: 10.3389/fnhum.2021.781234]
  20. Donaldson KR, Jonas K, Foti D, Larsen EM, Mohanty A, Kotov R (2022) Mismatch negativity and clinical trajectories in psychotic disorders: five-year stability and predictive utility. Psychol Med. https://doi.org/10.1017/S0033291722003075 [DOI: 10.1017/S0033291722003075]
  21. N����t��nen R, Sussman ES, Salisbury D, Shafer VL (2014) Mismatch negativity (MMN) as an index of cognitive dysfunction. Brain Topogr 27(4):451���466. https://doi.org/10.1007/s10548-014-0374-6 [DOI: 10.1007/s10548-014-0374-6]
  22. Donaldson KR, Novak KD, Foti D, Marder M, Perlman G, Kotov R, Mohanty A (2020) Associations of mismatch negativity with psychotic symptoms and functioning transdiagnostically across psychotic disorders. J Abnorm Psychol 129(6):570���580. https://doi.org/10.1037/abn0000506 [DOI: 10.1037/abn0000506]
  23. Kreml����ek J, Kreegipuu K, Tales A, Astikainen P, P��ldver N, N����t��nen R, Stefanics G (2016) Visual mismatch negativity (vMMN): a review and meta-analysis of studies in psychiatric and neurological disorders. Cortex 80:76���112. https://doi.org/10.1016/j.cortex.2016.03.017 [DOI: 10.1016/j.cortex.2016.03.017]
  24. Hedge C, Stothart G, Todd Jones J, Rojas Fr��as P, Magee KL, Brooks JC (2015) A frontal attention mechanism in the visual mismatch negativity. Behav Brain Res 293:173���181. https://doi.org/10.1016/j.bbr.2015.07.022 [DOI: 10.1016/j.bbr.2015.07.022]
  25. Tse CY, Tien KR, Penney TB (2006) Event-related optical imagingreveals the temporal dynamics of right temporal and frontal cortex activation in pre-attentive change detection. Neuroimage 29(1):314���320. https://doi.org/10.1016/j.neuroimage.2005.07.013 [DOI: 10.1016/j.neuroimage.2005.07.013]
  26. Tse CY, Penney TB (2007) Preattentive change detection using the event-related optical signal. IEEE eng Med Biol Mag 26(4):52���58. https://doi.org/10.1109/memb.2007.384096 [DOI: 10.1109/memb.2007.384096]
  27. Tse CY, Penney TB (2008) On the functional role of temporal and frontal cortex activation in passive detection of auditory deviance. Neuroimage 41(4):1462���1470. https://doi.org/10.1016/j.neuroimage.2008.03.043 [DOI: 10.1016/j.neuroimage.2008.03.043]
  28. Tse CY, Rinne T, Ng KK, Penney TB (2013) The functional role of the frontal cortex in pre-attentive auditory change detection. Neuroimage 83:870���879. https://doi.org/10.1016/j.neuroimage.2013.07.037 [DOI: 10.1016/j.neuroimage.2013.07.037]
  29. Tse CY, Gratton G, Garnsey SM, Novak MA, Fabiani M (2015) read my lips: brain dynamics associated with audiovisual integration and deviance detection. J Cogn Neurosci 27(9):1723���1737. https://doi.org/10.1162/jocn_a_00812 [DOI: 10.1162/jocn_a_00812]
  30. Tse CY, Shum YH, Xiao XZ, Wang Y (2021) Fronto-occipitalmismatch responses in pre-attentive detection of visual changes: implication on a generic brain network underlying Mismatch Negativity (MMN). Neuroimage 244:118633. https://doi.org/10.1016/j.neuroimage.2021.118633 [DOI: 10.1016/j.neuroimage.2021.118633]
  31. Kowalczyk OS, Mehta MA, O���Daly OG, Criaud M (2021) Task-based functional connectivity in attention-deficit/hyperactivity disorder: a systematic review. Biol Psychiatry Global Open Sci 2(4):350���367. https://doi.org/10.1016/j.bpsgos.2021.10.006 [DOI: 10.1016/j.bpsgos.2021.10.006]
  32. Kemner C, Verbaten MN, Koelega HS, Buitelaar JK, van der Gaag RJ, Camfferman G, van Engeland H (1996) Event-related brain potentials in children with attention-deficit and hyperactivity disorder: effects of stimulus deviancy and task relevance in the visual and auditory modality. Biol Psychiat 40(6):522���534. https://doi.org/10.1016/0006-3223(95)00429-7 [DOI: 10.1016/0006-3223(95)00429-7]
  33. Kim S, Baek JH, Kwon YJ, Lee HY, Yoo JH, Shim SH, Kim JS (2021) Machine-learning-based diagnosis of drug-naive adult patients with attention-deficit hyperactivity disorder using mismatch negativity. Transl Psychiatry 11(1):484. https://doi.org/10.1038/s41398-021-01604-3 [DOI: 10.1038/s41398-021-01604-3]
  34. Kilpel��inen R, Partanen J, Karhu J (1999) Reduced mismatch negativity (MMN) suggests deficits in pre-attentive auditory processing in distractible children. NeuroReport 10(16):3341���3345. https://doi.org/10.1097/00001756-199911080-00016 [DOI: 10.1097/00001756-199911080-00016]
  35. Lee YJ, Jeong MY, Kim JH, Kim JS (2020) Associations between the mismatch-negativity potential and symptom severity in medication-na��ve children and adolescents with symptoms of attention deficit/hyperactivity disorder. Clin Psychopharmacol Neurosci 18(2):249���260. https://doi.org/10.9758/cpn.2020.18.2.249 [DOI: 10.9758/cpn.2020.18.2.249]
  36. Rothenberger A, Banaschewski T, Heinrich H, Moll GH, Schmidt MH, van���t Klooster, B. (2000) Comorbidity in ADHD-children: effects of coexisting conduct disorder or tic disorder on event-related brain potentials in an auditory selective-attention task. Eur Arch Psychiatry Clin Neurosci 250(2):101���110. https://doi.org/10.1007/s004060070042 [DOI: 10.1007/s004060070042]
  37. Winsberg BG, Javitt DC, Silipo GS, Doneshka P (1993) Mismatch negativity in hyperactive children: effects of methylphenidate. Psychopharmacol Bull 29(2):229���233 [PMID: 8290670]
  38. Hsieh MH, Chien YL, Gau SS (2021) Mismatch negativity and P3a in drug-naive adults with attention-deficit hyperactivity disorder. Psychol Med. https://doi.org/10.1017/S0033291720005516 [DOI: 10.1017/S0033291720005516]
  39. Yamamuro K, Ota T, Iida J, Nakanishi Y, Kishimoto N, Kishimoto T (2016) Associations between the mismatch-negativity component and symptom severity in children and adolescents with attention deficit/hyperactivity disorder. Neuropsychiatr Dis Treat 12:3183���3190. https://doi.org/10.2147/NDT.S120540 [DOI: 10.2147/NDT.S120540]
  40. Gomes H, Duff M, Flores A, Halperin JM (2013) Automatic processing of duration in children with attention-deficit/hyperactivity disorder. J Int Neuropsychol Soc 19(6):686���694. https://doi.org/10.1017/S1355617713000258 [DOI: 10.1017/S1355617713000258]
  41. Huttunen-Scott T, Kaartinen J, Tolvanen A, Lyytinen H (2008) Mismatch negativity (MMN) elicited by duration deviations in children with reading disorder, attention deficit or both. Int J Psychophysiol 69(1):69���77. https://doi.org/10.1016/j.ijpsycho.2008.03.002 [DOI: 10.1016/j.ijpsycho.2008.03.002]
  42. Kemner C, Verbaten MN, Cuperus JM, Camfferman G, van Engeland H (1995) Auditory event-related brain potentials in autistic children and three different control groups. Biol Psychiat 38(3):150���165. https://doi.org/10.1016/0006-3223(94)00247-Z [DOI: 10.1016/0006-3223(94)00247-Z]
  43. Oades RD, Dittmann-Balcar A, Schepker R, Eggers C, Zerbin D (1996) Auditory event-related potentials (ERPs) and mismatch negativity (MMN) in healthy children and those with attention-deficit or tourette/tic symptoms. Biol Psychol 43(2):163���185. https://doi.org/10.1016/0301-0511(96)05189-7 [DOI: 10.1016/0301-0511(96)05189-7]
  44. Rydkj��r J, M��llegaard Jepsen JR, Pagsberg AK, Fagerlund B, Glenth��j BY, Oranje B (2017) Mismatch negativity and P3a amplitude in young adolescents with first-episode psychosis: a comparison with ADHD. Psychol Med 47(2):377���388. https://doi.org/10.1017/S0033291716002518 [DOI: 10.1017/S0033291716002518]
  45. le Sommer J, Low AM, M��llegaard Jepsen JR, Fagerlund B, Vangkilde S, Habekost T, Glenth��j B, Oranje B (2021) Effects of methylphenidate on mismatch negativity and P3a amplitude of initially psychostimulant-na��ve, adult ADHD patients. Psychol Med. https://doi.org/10.1017/S0033291721002373 [DOI: 10.1017/S0033291721002373]
  46. Winsberg BG, Javitt DC, Silipo GS (1997) Electrophysiological indices of information processing in methylphenidate responders. Biol Psychiat 42(6):434���445. https://doi.org/10.1016/s0006-3223(96)00429-5 [DOI: 10.1016/s0006-3223(96)00429-5]
  47. Cl��ry H, Roux S, Houy-Durand E, Bonnet-Brilhault F, Bruneau N, Gomot M (2013) Electrophysiological evidence of atypical visual change detection in adults with autism. Front Hum Neurosci 7:62. https://doi.org/10.3389/fnhum.2013.00062 [DOI: 10.3389/fnhum.2013.00062]
  48. Kovarski K, Latinus M, Charpentier J, Cl��ry H, Roux S, Houy-Durand E, Saby A, Bonnet-Brilhault F, Batty M, Gomot M (2017) Facial expression related vMMN: disentangling emotional from neutral change detection. Front Hum Neurosci 11:18. https://doi.org/10.3389/fnhum.2017.00018 [DOI: 10.3389/fnhum.2017.00018]
  49. Neuhaus AH, Brandt ES, Goldberg TE, Bates JA, Malhotra AK (2013) Evidence for impaired visual prediction error in schizophrenia. Schizophr Res 147(2���3):326���330. https://doi.org/10.1016/j.schres.2013.04.004 [DOI: 10.1016/j.schres.2013.04.004]
  50. Urban A, Kreml��cek J, Masopust J, Libiger J (2008) Visual mismatch negativity among patients with schizophrenia. Schizophr Res 102(1���3):320���328. https://doi.org/10.1016/j.schres.2008.03.014 [DOI: 10.1016/j.schres.2008.03.014]
  51. Vogel BO, Stasch J, Walter H, Neuhaus AH (2018) Emotional context restores cortical prediction error responses in schizophrenia. Schizophr Res 197:434���440. https://doi.org/10.1016/j.schres.2018.02.030 [DOI: 10.1016/j.schres.2018.02.030]
  52. Corbisiero S, Riecher-R��ssler A, Buchli-Kammermann J, Stieglitz RD (2017) Symptom overlap and screening for symptoms of attention-deficit/hyperactivity disorder and psychosis risk in help-seeking psychiatric patients. Front Psych 8:206. https://doi.org/10.3389/fpsyt.2017.00206 [DOI: 10.3389/fpsyt.2017.00206]
  53. van der Meer JM, Oerlemans AM, van Steijn DJ, Lappenschaar MG, de Sonneville LM, Buitelaar JK, Rommelse NN (2012) Are autism spectrum disorder and attention-deficit/hyperactivity disorder different manifestations of one overarching disorder? Cognitive and symptom evidence from a clinical and population-based sample. J Am Acad Child Adolesc Psychiatry 51(11):1160-1172.e3. https://doi.org/10.1016/j.jaac.2012.08.024 [DOI: 10.1016/j.jaac.2012.08.024]
  54. Association AP (ed) (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Association, Arlinton
  55. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC (1998) The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59(Suppl 20):22���57 [PMID: 9881538]
  56. File D, File B, Bodn��r F, Sulykos I, Kecsk��s-Kov��cs K, Czigler I (2017) Visual mismatch negativity (vMMN) for low- and high-level deviances: a control study. Atten Percept Psychophys 79(7):2153���2170. https://doi.org/10.3758/s13414-017-1373-y [DOI: 10.3758/s13414-017-1373-y]
  57. Hayes AF (2012) PROCESS���: a versatile computational tool for mediation, moderation, and conditional process analysis. University of Kansas, KS
  58. Dunn W (1997) The impact of sensory processing abilities on the daily lives of young children and their families: a conceptual model. Infants Young Child 9:23���35 [DOI: 10.1097/00001163-199704000-00005]
  59. Dunn W (2007) Supporting children to participate successfully in everyday life by using sensory processing knowledge. Infants Young Child 20(2):84���101 [DOI: 10.1097/01.IYC.0000264477.05076.5d]
  60. Kimura M, Katayama J, Ohira H, Schr��ger E (2009) Visual mismatchnegativity: new evidence from the equiprobable paradigm. Psychophysiology 46(2):402���409. https://doi.org/10.1111/j.1469-8986.2008.00767.x [DOI: 10.1111/j.1469-8986.2008.00767.x]
  61. Stefanics G, Kreml����ek J, Czigler I (2014) Visual mismatch negativity: a predictive coding view. Front Hum Neurosci 8:666. https://doi.org/10.3389/fnhum.2014.00666 [DOI: 10.3389/fnhum.2014.00666]
  62. Ahmadi N, Goodarzi MA, Hadianfard H, Mohamadi N, Farid D, Kholasehzadeh G, Sakhvidi MN, Hemyari C (2013) Comparing Iconic Memory in Children with and without Attention Deficit Hyperactivity Disorder. Iran J Psychiatry 8(3):131���137 [PMID: 24454422]
  63. Li J, Wang W, Cheng J, Li H, Feng L, Ren Y, Liu L, Qian Q, Wang Y (2022) Relationships between sensory integration and the core symptoms of attention-deficit/hyperactivity disorder: the mediating effect of executive function. Eur Child Adolesc Psychiatry. https://doi.org/10.1007/s00787-022-02069-5 [DOI: 10.1007/s00787-022-02069-5]

Grants

  1. 81971284/National Natural Sciences Foundation of China
  2. 81771479/National Natural Sciences Foundation of China
  3. 32271094/National Natural Sciences Foundation of China
  4. LS, 2020-1-4111/the Key scientific research projects of capital health development
  5. LS, Z171100001017089/the Beijing Municipal Science and Technology Program

MeSH Term

Humans
Male
Female
Adult
Attention Deficit Disorder with Hyperactivity
Electroencephalography
Executive Function
Young Adult
Visual Perception
Evoked Potentials, Visual
Evoked Potentials
Neuropsychological Tests
Journal Article

Word Cloud

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