COVID-19 infection and a repeated false positivity effect in HIV testing: A case report.

Anupama Balasubramanian, Devika Singh, Timothy Lahey
Author Information
  1. Anupama Balasubramanian: University of Vermont, Robert Larner College of Medicine, United States.
  2. Devika Singh: University of Vermont, Robert Larner College of Medicine, United States.
  3. Timothy Lahey: University of Vermont, Robert Larner College of Medicine, United States.

Abstract

Several reports in the literature have described the association between SARS-CoV-2 infection and false positive HIV testing results. We present a case of a cisgender male who has sex with men with a false positive HIV test after fully recovering from COVID-19 14 days prior. Initial 4th generation HIV 1 and 2 antibody/antigen testing was positive twice, but confirmatory antibody testing was negative. HIV viral load was persistently undetectable. Most of the previously published case reports describe concurrent testing and positivity for HIV and COVID-19. Our report stands out due to the implication of a potentially prolonged association that could persist for several weeks.

Keywords

References

  1. Indian J Med Res. 2013 Sep;138(3):291-3 [PMID: 24135172]
  2. Nature. 2021 Jul;595(7866):283-288 [PMID: 34010947]
  3. Cureus. 2023 Jan 23;15(1):e34096 [PMID: 36843732]
  4. J Transl Autoimmun. 2021;4:100091 [PMID: 33681751]
  5. Clin Infect Dis. 2023 Aug 22;77(4):615-619 [PMID: 37158382]
  6. Chin Med Sci J. 2014 Jun;29(2):103-6 [PMID: 24998232]
  7. Biology (Basel). 2022 Oct 19;11(10): [PMID: 36290433]
  8. Int J Biol Sci. 2022 Jul 11;18(12):4768-4780 [PMID: 35874958]
  9. J Glob Infect Dis. 2022 Feb 28;14(1):43-44 [PMID: 35418733]
  10. Immunobiology. 2021 Jul;226(4):152110 [PMID: 34242877]
  11. AIDS. 2021 Jul 15;35(9):1521-1522 [PMID: 34185720]
  12. Rheumatol Int. 2021 Sep;41(9):1657-1665 [PMID: 33944985]
  13. J Clin Pathol. 2021 Sep;74(9):614 [PMID: 32907911]
  14. Diabetes Metab Syndr. 2022 Dec;16(12):102660 [PMID: 36351871]
  15. AIDS. 2023 May 1;37(6):947-950 [PMID: 36779499]
  16. BMJ. 2021 Jul 26;374:n1648 [PMID: 34312178]
  17. Ann Med Surg (Lond). 2021 Nov;71:103027 [PMID: 34777794]

Word Cloud

Created with Highcharts 10.0.0HIVpositivetestingCOVID-19falsecasereportsassociationinfectionpositivityreportSeveralliteraturedescribedSARS-CoV-2resultspresentcisgendermalesexmentestfullyrecovering14dayspriorInitial4thgeneration12antibody/antigentwiceconfirmatoryantibodynegativeviralloadpersistentlyundetectablepreviouslypublisheddescribeconcurrentstandsdueimplicationpotentiallyprolongedpersistseveralweeksrepeatedeffecttesting:Cross-reactivityFalse

Similar Articles

Cited By