A Moderated Mediation Model of the Influence of Cynical Distrust, Medical Mistrust, and Anger on Vaccination Hesitancy in Nursing Staff.

Athanasios Tselebis, Christos Sikaras, Charalampos Milionis, Eleni Paraskevi Sideri, Konstantinos Fytsilis, Styliani Maria Papageorgiou, Ioannis Ilias, Argyro Pachi
Author Information
  1. Athanasios Tselebis: Psychiatric Department, Sotiria Thoracic Diseases Hospital of Athens, 11527 Athens, Greece. ORCID
  2. Christos Sikaras: Nursing Department, Sotiria Thoracic Diseases Hospital of Athens, 11527 Athens, Greece. ORCID
  3. Charalampos Milionis: Department of Endocrinology, Diabetes and Metabolism, Elena Venizelou General and Maternity Hospital, 11521 Athens, Greece.
  4. Eleni Paraskevi Sideri: Emergency Department of General Hospital of Athens Korgialeneio-Benakeio Hellenic Red Cross, 11526 Athens, Greece.
  5. Konstantinos Fytsilis: Psychiatric Department, Sotiria Thoracic Diseases Hospital of Athens, 11527 Athens, Greece.
  6. Styliani Maria Papageorgiou: Psychiatric Department, Sotiria Thoracic Diseases Hospital of Athens, 11527 Athens, Greece.
  7. Ioannis Ilias: Department of Endocrinology, Diabetes and Metabolism, Elena Venizelou General and Maternity Hospital, 11521 Athens, Greece. ORCID
  8. Argyro Pachi: Psychiatric Department, Sotiria Thoracic Diseases Hospital of Athens, 11527 Athens, Greece. ORCID

Abstract

During the pandemic, nurses experienced anger that stemmed from a sense of threat, frustration, or even a sense of injustice. The purpose of this study was to examine the relationship between vaccination hesitancy, anger, cynicism, and medical mistrust among nurses, as there are no relevant studies in the literature. This study was conducted online by completing self-report questionnaires. The Dimensions of Anger Reactions-5, the 8-item "Cynical Distrust" scale, and the Medical Mistrust Multiformat Scale were used. For vaccination hesitancy, two questions with a 5-point scale were used: one question examining hesitancy to get vaccinated with the COVID-19 vaccine, and another question examining hesitancy to get vaccinated with the influenza vaccine. In total, 387 nurses (66 men and 321 women) participated in this study. Nurses showed statistically greater hesitancy toward the COVID-19 vaccine compared to hesitancy toward the influenza vaccine. The variation in vaccine hesitancy was explained by the scores in the Medical Mistrust Multiformat Scale, the Dimensions of Anger Reactions, and the Cynical Distrust Scale. The Medical Mistrust Multiformat Scale mediated the relationship between the Cynical Distrust Scale and total vaccine hesitancy. The Dimensions of Anger Reactions Scale significantly moderated the indirect effect of the Cynical Distrust Scale on total vaccine hesitancy through the Medical Mistrust Multiformat Scale. In conclusion, it is highly likely that anger is involved in reported vaccine hesitancy both by activating schemas of distrust in others and by adopting anti-systemic views of mistrust in the medical system.

Keywords

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