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Antibiotics (Basel, Switzerland)
Jan 18, 2024;13 (1):

Effects of a Primary Care Antimicrobial Stewardship Program on Meticillin-Resistant Strains across a Region of Catalunya (Spain) over 5 Years.

Alfredo Jover-S��enz, Mar��a Ram��rez-Hidalgo, Alba Bell��s Bell��s, Esther Ribes Murillo, Meritxell Batlle Bosch, Anna Rib�� Mir��, Alba Mari L��pez, Jos�� Cayado Cabanillas, Neus Piqu�� Palac��n, S��nia Garrido-Calvo, Mireia Ortiz Valls, Mar��a Isabel Gracia Vilas, Laura Gros Nav��s, Mar��a Jes��s Javierre Caudevilla, Lidia Montull Navarro, Cecilia Ba��eres Argiles, Pilar Vaqu�� Castilla, Jos�� Javier Ichart Tom��s, Mireia Saura Codina, Ester Andreu Mayor, Roser Martorell Sol��, Ana Vena Mart��nez, Jos�� Manuel Albalad Samper, Susana Cano Marr��n, Cristina Soler Elcacho, Andr��s Rodr��guez Garrocho, Gemma Terrer Manrique, Antoni Sol�� Curc��, David de la Rica Escuin, Mar��a Jos�� Estadella Servalls, Ana M Figueres Farreny, Lu��s Miguel Monta��a Esteban, Lidia Sanz Borrell, Arancha Morales Valle, Merc�� Pallerola Planes, Aly Hamadi, Francesc Pujol Aymerich, Francisca Toribio Redondo, Mar��a Cruz Urgel��s Castill��n, Juan Valga��on Palacios, Marc Olivart Parejo, Joan Torres-Puig-Gros
Author Information
  1. Alfredo Jover-S��enz: Unidad Territorial Infecci��n Nosocomial (UTIN), Hospital Universitari Arnau de Vilanova de Lleida (HUAV), 25198 Lleida, Spain. ORCID
  2. Mar��a Ram��rez-Hidalgo: Unidad Territorial Infecci��n Nosocomial (UTIN), Hospital Universitari Arnau de Vilanova de Lleida (HUAV), 25198 Lleida, Spain.
  3. Alba Bell��s Bell��s: Secci��n de Microbiolog��a, Hospital Universitari Arnau de Vilanova de Lleida (HUAV), 25198 Lleida, Spain. ORCID
  4. Esther Ribes Murillo: Unidad de Farmacia de Atenci��n Primaria, Institut Catal�� de la Salut (ICS), 25007 Lleida, Spain.
  5. Meritxell Batlle Bosch: Equipo de Atenci��n Priamaria (EAP) Les Borges Blanques, 25400 Lleida, Spain.
  6. Anna Rib�� Mir��: Equipo de Atenci��n Priamaria (EAP) Les Borges Blanques, 25400 Lleida, Spain.
  7. Alba Mari L��pez: EAP Pla d'Urgell, 25001 Lleida, Spain.
  8. Jos�� Cayado Cabanillas: EAP Pla d'Urgell, 25001 Lleida, Spain. ORCID
  9. Neus Piqu�� Palac��n: EAP Pla d'Urgell, 25001 Lleida, Spain.
  10. S��nia Garrido-Calvo: EAP Bal��fia-Pardinyes, 25005 Lleida, Spain.
  11. Mireia Ortiz Valls: EAP Bal��fia-Pardinyes, 25005 Lleida, Spain.
  12. Mar��a Isabel Gracia Vilas: EAP Rambla de Ferran, 25007 Lleida, Spain.
  13. Laura Gros Nav��s: EAP Lleida Rural Nord, 25110 Lleida, Spain.
  14. Mar��a Jes��s Javierre Caudevilla: Centre Penitenciari de Ponent, 25199 Lleida, Spain.
  15. Lidia Montull Navarro: EAP Eixample, 25006 Lleida, Spain.
  16. Cecilia Ba��eres Argiles: EAP Eixample, 25006 Lleida, Spain.
  17. Pilar Vaqu�� Castilla: EAP Primer de Maig, 25002 Lleida, Spain.
  18. Jos�� Javier Ichart Tom��s: Servicio de Urgencias, Hospital Universitari Arnau de Vilanova de Lleida (HUAV), 25198 Lleida, Spain.
  19. Mireia Saura Codina: Servicio de Urgencias, Hospital Universitari Arnau de Vilanova de Lleida (HUAV), 25198 Lleida, Spain.
  20. Ester Andreu Mayor: Col��legi Oficial de Pod��legs, 25001 Lleida, Spain.
  21. Roser Martorell Sol��: EAP Cervera, 25200 Lleida, Spain.
  22. Ana Vena Mart��nez: Servei de Geriatria, Hospital Universitari Santa Maria, 25198 Lleida, Spain.
  23. Jos�� Manuel Albalad Samper: EAP Ponts, 25740 Lleida, Spain.
  24. Susana Cano Marr��n: EAP Onze de Setembre, 25005 Lleida, Spain.
  25. Cristina Soler Elcacho: EAP Onze de Setembre, 25005 Lleida, Spain.
  26. Andr��s Rodr��guez Garrocho: EAP Onze de Setembre, 25005 Lleida, Spain. ORCID
  27. Gemma Terrer Manrique: EAP Onze de Setembre, 25005 Lleida, Spain.
  28. Antoni Sol�� Curc��: EAP Bellpuig, 25250 Lleida, Spain.
  29. David de la Rica Escuin: EAP Artesa de Segre, 25730 Lleida, Spain.
  30. Mar��a Jos�� Estadella Servalls: EAP Cappont, 25001 Lleida, Spain.
  31. Ana M Figueres Farreny: EAP Almacelles, 25100 Lleida, Spain.
  32. Lu��s Miguel Monta��a Esteban: EAP Ser��s, 25183 Lleida, Spain.
  33. Lidia Sanz Borrell: EAP Ser��s, 25183 Lleida, Spain.
  34. Arancha Morales Valle: EAP Lleida Rural Sud, 25171 Lleida, Spain.
  35. Merc�� Pallerola Planes: EAP Balaguer, 25600 Lleida, Spain.
  36. Aly Hamadi: EAP Balaguer, 25600 Lleida, Spain.
  37. Francesc Pujol Aymerich: EAP Alcarr��s, 25180 Lleida, Spain.
  38. Francisca Toribio Redondo: EAP Alfarr��s-Almenar, 25120 Lleida, Spain.
  39. Mar��a Cruz Urgel��s Castill��n: EAP Bordeta-Magraners, 25001 Lleida, Spain.
  40. Juan Valga��on Palacios: EAP La Granadella, 25177 Lleida, Spain.
  41. Marc Olivart Parejo: EAP T��rrega, 25300 Lleida, Spain.
  42. Joan Torres-Puig-Gros: Departament de Salut P��blica, Universitat de Lleida (UdL), 25006 Lleida, Spain.
PMID: 38247651 DOI: 10.3390/antibiotics13010092

Abstract

Primary care antimicrobial stewardship program (ASP) interventions can reduce the over-prescription of unnecessary antibiotics, but the impact on the reduction in bacterial resistance is less known, and there is a lack of available data. We implemented a prolonged educational counseling ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, which was compared to a pre-intervention period, a significant reduction in antibiotic prescriptions occurred, particularly those associated with greater harmful effects and resistance selection. There was also a decrease in methicillin-resistant (MRSA) strains and in their co-resistance to other antibiotics, particularly those with an ecological impact.

Keywords

MRSA antimicrobial stewardship community-onset epidemiology multidrug-resistant microorganisms use antimicrobials

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Journal Article

Word Cloud

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