Bayesian spatio-temporal analysis of the COVID-19 pandemic in Catalonia.

Pau Satorra, Cristian Tebé
Author Information
  1. Pau Satorra: Biostatistics Support and Research Unit, Germans Trias i Pujol Research Institute and Hospital (IGTP), Badalona, Barcelona, Spain.
  2. Cristian Tebé: Biostatistics Support and Research Unit, Germans Trias i Pujol Research Institute and Hospital (IGTP), Badalona, Barcelona, Spain. ctebe@igtp.cat.

Abstract

In this study, we modelled the incidence of COVID-19 cases and hospitalisations by basic health areas (ABS) in Catalonia. Spatial, temporal and spatio-temporal incidence trends were described using estimation methods that allow to borrow strength from neighbouring areas and time points. Specifically, we used Bayesian hierarchical spatio-temporal models estimated with Integrated Nested Laplace Approximation (INLA). An exploratory analysis was conducted to identify potential ABS factors associated with the incidence of cases and hospitalisations. High heterogeneity in cases and hospitalisation incidence was found between ABS and along the waves of the pandemic. Urban areas were found to have a higher incidence of COVID-19 cases and hospitalisations than rural areas, while socio-economic deprivation of the area was associated with a higher incidence of hospitalisations. In addition, full vaccination coverage in each ABS showed a protective effect on the risk of COVID-19 cases and hospitalisations.

References

  1. Stat Methods Med Res. 2016 Aug;25(4):1080-100 [PMID: 27566767]
  2. Risk Manag Healthc Policy. 2021 Sep 13;14:3775-3782 [PMID: 34548826]
  3. Travel Med Infect Dis. 2021 Jan-Feb;39:101945 [PMID: 33278610]
  4. N Engl J Med. 2021 Apr 15;384(15):1412-1423 [PMID: 33626250]
  5. Stat Med. 2000 Sep 15-30;19(17-18):2555-67 [PMID: 10960871]
  6. Science. 2021 May 28;372(6545): [PMID: 33906968]
  7. Am J Epidemiol. 2021 Sep 1;190(9):1908-1917 [PMID: 33831148]
  8. J Reg Sci. 2021 Sep;61(4):849-881 [PMID: 34230688]
  9. Stat Methods Med Res. 2011 Feb;20(1):49-68 [PMID: 20547586]
  10. BMC Med. 2020 Sep 4;18(1):271 [PMID: 32883276]
  11. Transbound Emerg Dis. 2022 Sep;69(5):e2731-e2744 [PMID: 35751843]
  12. Sci Rep. 2022 Jun 7;12(1):9369 [PMID: 35672355]
  13. PLoS One. 2020 Oct 9;15(10):e0240286 [PMID: 33035253]
  14. Environ Res. 2020 Dec;191:110177 [PMID: 32931792]
  15. Lancet. 2021 May 15;397(10287):1819-1829 [PMID: 33964222]
  16. Geohealth. 2021 Aug 04;5(8):e2021GH000423 [PMID: 34377879]
  17. Public Health Rep. 2021 Nov-Dec;136(6):765-773 [PMID: 34388054]
  18. Lancet. 2022 Mar 5;399(10328):924-944 [PMID: 35202601]
  19. Stat Methods Med Res. 2016 Aug;25(4):1145-65 [PMID: 27566770]
  20. BMJ Glob Health. 2021 Jul;6(7): [PMID: 34321234]
  21. Pulmonology. 2021 Mar-Apr;27(2):110-115 [PMID: 32540223]
  22. Health Place. 2021 Jan;67:102460 [PMID: 33418438]
  23. BMC Public Health. 2022 Dec 12;22(1):2316 [PMID: 36503482]
  24. Sci Total Environ. 2021 Jul 20;779:146334 [PMID: 33744577]
  25. Ann Epidemiol. 2021 Oct;62:51-58 [PMID: 34048904]
  26. Appl Econ Perspect Policy. 2022 Sep;44(3):1591-1609 [PMID: 34900209]
  27. Sci Total Environ. 2021 Mar 20;761:144257 [PMID: 33352341]
  28. Geogr Anal. 2022 Jun 04;: [PMID: 36118737]
  29. Int J Environ Res Public Health. 2022 Jul 06;19(14): [PMID: 35886114]
  30. N Engl J Med. 2020 Dec 31;383(27):2603-2615 [PMID: 33301246]
  31. Spat Stat. 2022 Jun;49:100551 [PMID: 34782854]

Grants

  1. SGR 01421/Government of Catalonia | Departament d 'Universitats, Recerca i Societat de la Informaci ó (DURSI)

MeSH Term

Humans
Pandemics
Bayes Theorem
Spain
COVID-19
Spatio-Temporal Analysis

Word Cloud

Created with Highcharts 10.0.0incidencecaseshospitalisationsCOVID-19areasABSspatio-temporalCataloniaBayesiananalysisassociatedfoundpandemichigherstudymodelledbasichealthSpatialtemporaltrendsdescribedusingestimationmethodsallowborrowstrengthneighbouringtimepointsSpecificallyusedhierarchicalmodelsestimatedIntegratedNestedLaplaceApproximationINLAexploratoryconductedidentifypotentialfactorsHighheterogeneityhospitalisationalongwavesUrbanruralsocio-economicdeprivationareaadditionfullvaccinationcoverageshowedprotectiveeffectrisk

Similar Articles

Cited By (2)