[Update: Heart Failure with Preserved Ejection Fraction].

Caroline Morbach, Stefan Störk
Author Information
  1. Caroline Morbach: Medizinische Klinik und Poliklinik I, Deutsches Zentrum für Herzinsuffizienz, Universitätsklinikum Würzburg, Würzburg, Germany.
  2. Stefan Störk: Medizinische Klinik und Poliklinik I, Deutsches Zentrum für Herzinsuffizienz, Universitätsklinikum Würzburg, Würzburg, Germany.

Abstract

Heart failure with a preserved ejection fraction (HFpEF) is a multifaceted disease entity. Confirming the diagnosis as well as tailoring the most appropriate therapy remains an ongoing challenge. The 2021 heart failure guidelines of the European Society of Cardiology (ESC) suggested a simplified diagnostic approach, and the guideline update provided in 2023 gave recommendations regarding pharmacotherapy based on recent evidence. Further, the Heart Failure Association (HFA) and the European Heart Rhythm Association of the ESC jointly proposed a scheme how to classify HFpEF patients into phenogroups of distinct pathophysiology that may benefit from individually targeted treatment. Regarding HFpEF originating from secondary causes, e.g. M. Fabry, amyloidosis or hypertrophic cardiomyopathy, there are emerging therapeutic options with the potential to substantially improve the physical capacity, quality of life and prognosis in these patients. The here presented update gives an overview on the recent advances in the area of HFpEF.

MeSH Term

Humans
Heart Failure
Stroke Volume
Quality of Life
Prognosis
Cardiology

Word Cloud

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