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Mar, 2024;20 101747.

Craniofacial disorders and dysplasias: Molecular, clinical, and management perspectives.

Sunday O Akintoye, Akinyele O Adisa, Chukwubuzor U Okwuosa, Mel Mupparapu
Author Information
  1. Sunday O Akintoye: Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  2. Akinyele O Adisa: University of Ibadan and University College Hospital Ibadan, Ibadan, Nigeria.
  3. Chukwubuzor U Okwuosa: Department of Oral Pathology & Oral Medicine, University of Nigeria Teaching Hospital, Ituku-Ozalla, Nigeria.
  4. Mel Mupparapu: Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
PMID: 38566929 DOI: 10.1016/j.bonr.2024.101747

Abstract

There is a wide spectrum of craniofacial bone disorders and dysplasias because embryological development of the craniofacial region is complex. Classification of craniofacial bone disorders and dysplasias is also complex because they exhibit complex clinical, pathological, and molecular heterogeneity. Most craniofacial disorders and dysplasias are rare but they present an array of phenotypes that functionally impact the orofacial complex. Management of craniofacial disorders is a multidisciplinary approach that involves the collaborative efforts of multiple professionals. This review provides an overview of the complexity of craniofacial disorders and dysplasias from molecular, clinical, and management perspectives.

Keywords

Craniofacial disorder Dysplasia Orofacial Skeletal disorders

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Grants

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