Sensing of Quercetin With Cobalt-Doped Manganese Nanosystems by Electrochemical Method.

Sree Thalir, Sherin Celshia Susai, Muthamizh Selvamani, Vasugi Suresh, Sathya Sethuraman, Karthikeyan Ramalingam
Author Information
  1. Sree Thalir: Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
  2. Sherin Celshia Susai: Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
  3. Muthamizh Selvamani: Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
  4. Vasugi Suresh: Medical Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
  5. Sathya Sethuraman: Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
  6. Karthikeyan Ramalingam: Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Abstract

BACKGROUND: The pressing need for precise, quick, and affordable detection of diverse biomolecules has led to notable developments in the realm of biosensors. Quercetin, a biomolecule rich in flavonoids predominantly found in our diet, is sensed by the electrochemical method. The electrochemical properties show remarkable improvement when MnO (MO) is doped with cobalt (Co).  Aim: This study aimed to investigate the biomolecule sensing of quercetin using Co-doped MO by electrochemical method.  Materials and methods: Co-doped MO nanospheres were prepared by hydrothermal method. The crystal structure of the synthesized material was evaluated by using X-ray diffraction analysis. The sample morphology was assessed by using field emission scanning electron microscopy (FE-SEM) techniques. The cyclic voltammetry technique was used for the detection of quercetin biomolecules.  Results: The synthesized Co-doped MO appeared to be spherical in morphology in FE-SEM. Energy-dispersive X-ray spectroscopy showed the only presence of Co, Mn, and O, which confirmed the purity of the sample. The modified electrode sensed the biomolecule with a higher current of 7.35 µA than the bare glassy carbon electrode of 6.1 µA.
CONCLUSION: The Co-doped MO exhibited enhanced conductivity, reactivity, and electrochemical performance. This tailored approach will help in the optimization of material properties toward specific biomolecule sensing applications.

Keywords

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Word Cloud

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