Acute effect of an exogenous ketone monoester supplement on appetite and food intake in adults with type 2 diabetes.

Barbara Oliveira, Kaja Falkenhain, Brenda M Davy, Kevin P Davy, Jonathan P Little
Author Information
  1. Barbara Oliveira: School of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.
  2. Kaja Falkenhain: School of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada.
  3. Brenda M Davy: Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA, US.
  4. Kevin P Davy: Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA, US.
  5. Jonathan P Little: School of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, Canada. ORCID

Abstract

The effects of exogenous ketones on appetite and food intake remain elusive, especially for people with type 2 diabetes (T2D). This study aimed to determine whether acute ingestion of an oral ketone monoester supplement (KME) affected appetite sensations, prospective food consumption and intake in T2D. Results showed that acute KME ingestion did not significantly alter appetite scores. However, there was a tendency for lower energy intake during an ad libitum meal 3 h following ketone ingestion compared to non-energetic placebo. Further research is warranted to understand the long-term effects of exogenous ketones for energy and macronutrient intake in T2D.

Keywords

MeSH Term

Humans
Diabetes Mellitus, Type 2
Dietary Supplements
Male
Middle Aged
Appetite
Ketones
Female
Eating
Aged
Energy Intake
Adult
Double-Blind Method
Cross-Over Studies

Chemicals

Ketones

Word Cloud

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