First report of infection in an immunocompetent patient in Zhejiang province.

Wei Pan, Bingqian Zhuo, Sumei Wang, Jieping Long, Wei Xu, Mengyuan Chen, Xin Hong, Yumei Ge
Author Information
  1. Wei Pan: Department of Clinical Laboratory, Haiyan People's Hospital, Haiyan, Zhejiang, 314300, China.
  2. Bingqian Zhuo: School of Public Health, Hangzhou Medical College, Hangzhou, 310053, China.
  3. Sumei Wang: Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
  4. Jieping Long: Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
  5. Wei Xu: School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
  6. Mengyuan Chen: The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
  7. Xin Hong: Department of Green Pharmaceutical Collaborative Innovation Center, School of Pharmacy, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.
  8. Yumei Ge: Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.

Abstract

Nocardiosis is an infectious disease caused by spp., mainly affecting immunocompromised hosts. infection is not common; especially infection is even rarer. The patient, female, 61 years old, farmer, has been working in the field for a long time and has normal immune function. Her main clinical manifestation was persistent back pain. Chest-enhanced computed tomography showed pulmonary inflammation. Rare pathogen ei was detected in alveolar lavage fluid using matrix-assisted laser destructive ionization time-of-flight mass spectrometry. She received treatment with linezolid and was discharged after her condition improved.

Keywords

References

  1. Int J Infect Dis. 2023 May;130:136-143 [PMID: 36871785]
  2. Enferm Infecc Microbiol Clin (Engl Ed). 2021 Apr;39(4):192-200 [PMID: 32345492]
  3. Microbiol Resour Announc. 2020 Nov 19;9(47): [PMID: 33214300]
  4. Int J Dermatol. 2018 May;57(5):580-582 [PMID: 29399787]
  5. Front Cell Infect Microbiol. 2023 Aug 16;13:1229298 [PMID: 37655298]
  6. Clin Microbiol Rev. 2006 Apr;19(2):259-82 [PMID: 16614249]
  7. J Int Med Res. 1993 Jan-Feb;21(1):1-14 [PMID: 8319816]
  8. Mini Rev Med Chem. 2020;20(19):2052-2066 [PMID: 32888265]
  9. Chemotherapia (Basel). 1968;13(2):65-80 [PMID: 5656117]
  10. Infect Drug Resist. 2023 Jan 13;16:263-268 [PMID: 36660347]
  11. Drug Des Devel Ther. 2018 Jun 18;12:1759-1767 [PMID: 29950810]
  12. J Clin Microbiol. 2017 Dec 26;56(1): [PMID: 29118169]
  13. Cureus. 2024 Jan 27;16(1):e53035 [PMID: 38410293]
  14. Clin Microbiol Rev. 2022 Dec 21;35(4):e0002721 [PMID: 36314911]
  15. Sci Rep. 2021 Aug 18;11(1):16742 [PMID: 34408177]
  16. Clin Microbiol Infect. 2021 Apr;27(4):550-558 [PMID: 33418019]
  17. New Microbes New Infect. 2016 Sep 23;14:83-84 [PMID: 27774152]
  18. Int J Infect Dis. 2017 Apr;57:13-20 [PMID: 28088585]
  19. J Med Case Rep. 2013 Apr 11;7:103 [PMID: 23577983]
  20. Saudi Med J. 2013 Jun;34(6):644-7 [PMID: 23756931]
  21. Microb Biotechnol. 2023 Apr;16(4):778-783 [PMID: 36541026]
  22. Can J Infect Dis Med Microbiol. 2009 Fall;20(3):e103-6 [PMID: 20808449]
  23. J Clin Microbiol. 2008 Apr;46(4):1178-84 [PMID: 18256227]
  24. Microorganisms. 2022 May 29;10(6): [PMID: 35744638]

Word Cloud

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