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Journal of personalized medicine
Jul 23, 2024;14 (8):

The Key Role of Nutritional Intervention in Delaying Disease Progression and the Therapeutic Management of Diabetic Kidney Disease-A Challenge for Physicians and Patients.

Ileana Peride, Miruna Anastasiu, Silvia Alexandra Serban, Mirela Tiglis, Razvan Ene, Ana-Maria Nechita, Tiberiu Paul Neagu, Ionel Alexandru Checherita, Andrei Niculae
Author Information
  1. Ileana Peride: Clinical Department No. 3, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania. ORCID
  2. Miruna Anastasiu: "Marie Skłodowska Curie" Children Emergency Clinical Hospital, 077120 Bucharest, Romania.
  3. Silvia Alexandra Serban: Emergency Clinical Hospital of Bucharest, 014461 Bucharest, Romania.
  4. Mirela Tiglis: Department of Anesthesia and Intensive Care, Emergency Clinical Hospital of Bucharest, 014461 Bucharest, Romania. ORCID
  5. Razvan Ene: Clinical Department No. 14, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  6. Ana-Maria Nechita: Department of Nephrology and Dialysis, "St. John" Emergency Clinical Hospital, 042122 Bucharest, Romania.
  7. Tiberiu Paul Neagu: Clinical Department No. 11, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania. ORCID
  8. Ionel Alexandru Checherita: Department of Nephrology, Ilfov County Emergency Clinical Hospital, 022104 Bucharest, Romania. ORCID
  9. Andrei Niculae: Clinical Department No. 3, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania. ORCID
PMID: 39201970 DOI: 10.3390/jpm14080778

Abstract

Chronic kidney disease (CKD) represents an increasingly common pathology that affects patients' quality of life, and it is frequently associated with a high mortality rate, especially in the final stages of the disease. At the same time, diabetes mellitus is a chronic disease that contributes to the increased number of patients with CKD through diabetic kidney disease (DKD). The alternation of hypoglycemia with hyperglycemia is a condition in the occurrence of microvascular complications of diabetes, including DKD, which involves structural and functional changes in the kidneys. The therapeutic management of diabetic nephropathy is a much-discussed topic, both from nutritional medical recommendations and a pharmacotherapy perspective. The diet starting point for patients with DKD is represented by a personalized and correct adjustment of macro- and micronutrients. The importance of nutritional status in DKD patients is given by the fact that it represents a modifiable factor, which contributes to the evolution and prognosis of the disease. Since, in most cases, it is necessary to restrict many types of food, malnutrition must be considered and avoided as much as possible.

Keywords

chronic kidney disease diabetic kidney disease nutrition regimen outcome

References

  1. Clin J Am Soc Nephrol. 2019 Oct 7;14(10):1441-1449 [PMID: 31551237]
  2. Elife. 2020 Apr 09;9: [PMID: 32271147]
  3. J Transl Med. 2022 Nov 5;20(1):510 [PMID: 36335368]
  4. Blood Purif. 2020;49(1-2):202-211 [PMID: 31851983]
  5. J Nutr. 2015 Jan;145(1):164S-169S [PMID: 25527675]
  6. N Engl J Med. 2016 Sep 1;375(9):905-6 [PMID: 27579659]
  7. Am J Kidney Dis. 2007 Feb;49(2 Suppl 2):S12-154 [PMID: 17276798]
  8. Semin Nephrol. 2004 May;24(3):225-43 [PMID: 15156528]
  9. Diabetes Metab J. 2023 Sep;47(5):575-594 [PMID: 37793979]
  10. Blood Purif. 2013;36(1):41-6 [PMID: 23735624]
  11. Kidney360. 2022 Jun 22;3(9):1611-1615 [PMID: 36245656]
  12. Minerva Med. 2018 Jun;109(3):218-228 [PMID: 29205998]
  13. Nutrients. 2022 Oct 21;14(20): [PMID: 36297103]
  14. Curr Opin Nephrol Hypertens. 2016 May;25(3):232-9 [PMID: 26890303]
  15. Medicine (Baltimore). 2024 Jan 19;103(3):e36804 [PMID: 38241565]
  16. Lancet. 2014 Jun 7;383(9933):1999-2007 [PMID: 24910231]
  17. Clin J Am Soc Nephrol. 2006 Mar;1(2):182-92 [PMID: 17699207]
  18. Diabetes Care. 2005 Jan;28(1):164-76 [PMID: 15616252]
  19. Clin J Am Soc Nephrol. 2011 Feb;6(2):257-64 [PMID: 21183586]
  20. Nutrients. 2017 Jul 31;9(8): [PMID: 28758978]
  21. Curr Diab Rep. 2017 Mar;17(3):15 [PMID: 28271467]
  22. Diabetol Metab Syndr. 2019 Jan 23;11:7 [PMID: 30679960]
  23. J Ren Nutr. 2004 Oct;14(4):208-13 [PMID: 15483780]
  24. Nutr Metab Cardiovasc Dis. 2011 Sep;21 Suppl 2:B32-48 [PMID: 21745730]
  25. J Sports Sci Med. 2004 Sep 01;3(3):118-30 [PMID: 24482589]
  26. Front Endocrinol (Lausanne). 2022 Dec 09;13:1079725 [PMID: 36568108]
  27. Clin Ther. 2007 Jul;29(7):1354-67 [PMID: 17825687]
  28. Diabetes Care. 2014 Oct;37(10):2864-83 [PMID: 25249672]
  29. Can J Cardiol. 2013 Feb;29(2):151-67 [PMID: 23351925]
  30. Nutrients. 2022 Jan 19;14(3): [PMID: 35276799]
  31. Nutrients. 2023 Aug 13;15(16): [PMID: 37630758]
  32. Atherosclerosis. 2014 Jun;234(2):320-8 [PMID: 24727233]
  33. Biomed Res Int. 2017;2017:3146524 [PMID: 29359147]
  34. Rev Assoc Med Bras (1992). 2018 Jan;64(1):85-92 [PMID: 29561946]
  35. Crit Rev Clin Lab Sci. 2017 Aug;54(5):326-342 [PMID: 28956668]
  36. Front Nephrol. 2023 Dec 14;3:1282818 [PMID: 38192517]
  37. Nutrients. 2020 Sep 02;12(9): [PMID: 32887293]
  38. Kidney Int. 2009 Dec;76(11):1199-206 [PMID: 19741589]
  39. Cochrane Database Syst Rev. 2023 Jan 3;1:CD014906 [PMID: 36594428]
  40. Nutrients. 2019 Apr 26;11(5): [PMID: 31035482]
  41. PLoS One. 2014 Nov 26;9(11):e110535 [PMID: 25427285]
  42. Am J Clin Nutr. 2021 Jul 1;114(1):303-313 [PMID: 33742197]
  43. J Ren Nutr. 2022 Nov;32(6):e1-e4 [PMID: 35842212]
  44. Front Immunol. 2022 Dec 19;13:1080456 [PMID: 36601125]
  45. J Ren Nutr. 2021 Mar;31(2):116-120.e1 [PMID: 32737016]
  46. Biomedicines. 2022 Apr 09;10(4): [PMID: 35453626]
  47. Nat Rev Endocrinol. 2012 Sep;8(9):515-6 [PMID: 22825399]
  48. J Am Soc Nephrol. 2004 Jan;15(1):234-7 [PMID: 14694178]
  49. Kidney Int. 2003 Jan;63(1):225-32 [PMID: 12472787]
  50. Diabetes Care. 2011 Jan;34(1):14-9 [PMID: 20929998]
  51. PLoS One. 2015 Dec 28;10(12):e0145505 [PMID: 26710078]
  52. Front Endocrinol (Lausanne). 2024 Apr 29;15:1385872 [PMID: 38742202]
  53. Clin J Am Soc Nephrol. 2014 Nov 7;9(11):1868-75 [PMID: 25359387]
  54. Diabetes Spectr. 2015 Aug;28(3):181-6 [PMID: 26300611]
  55. Curr Hypertens Rep. 2012 Oct;14(5):388-96 [PMID: 22846984]
  56. Front Endocrinol (Lausanne). 2016 Dec 23;7:164 [PMID: 28066329]
  57. J Am Heart Assoc. 2022 Jun 7;11(11):e025071 [PMID: 35647665]
  58. Clin Nutr ESPEN. 2022 Apr;48:21-35 [PMID: 35331493]
  59. Am J Med. 2002 Mar;112(4):298-304 [PMID: 11893369]
  60. J Postgrad Med. 2024 Jan-Mar;70(1):1-6 [PMID: 38247658]
  61. Kidney Int. 2022 Nov;102(5S):S1-S127 [PMID: 36272764]
  62. PLoS One. 2016 Jul 06;11(7):e0158765 [PMID: 27383068]
  63. Am J Kidney Dis. 2018 Jun;71(6):884-895 [PMID: 29398179]
  64. Clin Kidney J. 2019 Nov 08;13(2):253-260 [PMID: 32296529]
  65. Nephrology (Carlton). 2009 Dec;14(8):750-7 [PMID: 20025684]
  66. Am J Clin Nutr. 2022 May 1;115(5):1404-1417 [PMID: 34967847]
  67. Acta Diabetol. 2023 Oct;60(10):1365-1375 [PMID: 37347448]
  68. Metabolism. 2011 Jul;60(7):965-8 [PMID: 21036373]
  69. Nat Rev Nephrol. 2011 Feb;7(2):110-21 [PMID: 21135888]
  70. N Engl J Med. 2014 Apr 17;370(16):1514-23 [PMID: 24738668]
  71. Diabetes Care. 2019 Jan;42(Suppl 1):S13-S28 [PMID: 30559228]
  72. Biomol Ther (Seoul). 2021 Jul 1;29(4):365-372 [PMID: 33888647]
  73. Nutrients. 2020 Aug 04;12(8): [PMID: 32759714]
  74. Nutrients. 2019 Feb 05;11(2): [PMID: 30764511]
  75. Int Urol Nephrol. 2016 Jan;48(1):99-113 [PMID: 26438328]
  76. Saudi J Kidney Dis Transpl. 2016 Jul-Aug;27(4):710-6 [PMID: 27424687]
  77. Clin Nutr Res. 2014 Jan;3(1):64-8 [PMID: 24527422]
  78. J Nutr Health Aging. 2020;24(8):900-905 [PMID: 33009543]
  79. Am J Kidney Dis. 2020 Sep;76(3 Suppl 1):S1-S107 [PMID: 32829751]
  80. Diabetes Care. 2018 Jan;41(Suppl 1):S38-S50 [PMID: 29222375]
  81. Am J Kidney Dis. 2009 Apr;53(4):638-46 [PMID: 19167797]
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