Client-Centered Care Coordination (C4) for HIV/STI Prevention: a Theoretical, Conceptual, and Methodological Overview-HIV Prevention Trials Network (HPTN) 073.

LaRon E Nelson, Leo Wilton, Darren L Whitfield, Geoffrey C Williams, Kenneth H Mayer, Arnošt Komárek, Donte T Boyd, Geetha Beauchamp, Sheldon D Fields, Darrell P Wheeler, HPTN 073 Study Team
Author Information
  1. LaRon E Nelson: School of Nursing, Yale University, 400 West Campus Drive, New Haven, CT, 06477, USA.
  2. Leo Wilton: Department of Human Development, State University of New York at Binghamton, Binghamton, NY, USA.
  3. Darren L Whitfield: School of Social Work, University of Maryland Baltimore, Baltimore, MD, USA.
  4. Geoffrey C Williams: Billings Clinic, Billings, MT, USA.
  5. Kenneth H Mayer: Fenway Health, The Fenway Institute, Boston, MA, USA.
  6. Arnošt Komárek: Department of Probability and Mathematical Statistics, Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic.
  7. Donte T Boyd: College of Social Work, The Ohio State University, Columbus, OH, USA.
  8. Geetha Beauchamp: Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  9. Sheldon D Fields: School of Nursing, Pennsylvania State University, University Park, PA, USA.
  10. Darrell P Wheeler: Iona College, New Rochelle, NY, USA.

Abstract

Introduction: There are few culturally informed, theory-driven evidence-based strategies to support PrEP use among Black MSM. This paper describes the theoretical foundation and conceptual development of C4 to support the prevention of HIV and other STIs.
Methods: C4 integrates self-determination theory with comprehensive risk counseling and services using an integrative anti-racism lens. C4 was implemented in a 52-week HIV prevention demonstration project to facilitate PrEP use and adherence among Black MSM (=225) in three US cities from 2014-2017.
Results: PrEP use was 79%, with 91% of PrEP users starting within 30-days. 12-month retention in C4 was 92%. Care coordination encounters focused primarily on clients' needs related to PrEP adherence (43%) and sexual health (19%). Over the 12-month period, a substantial proportion of the men made progress towards their PrEP adherence goals at the 8-week (83%), 26-week (75%) and 52-week (81%) study visits.
Conclusions: C4 is a multi-level, multi-component intervention that dually targets individual-level motivations and capacities of Black MSM and the healthcare facility-level attitudes, behaviors and processes that characterize the climates where Black MSM receive services.
Policy Implications: Public health policy efforts to scale-up PrEP may consider C4 as a tool to optimize the use of PrEP and PrEP program retention with Black MSM. C4 is also a tool for healthcare facilities to transform their models of service delivery towards improving the implementation PrEP services, including ensuring racial equity in the prevention impact of novel PrEP formulations such as long-acting injectable and potential future long-acting oral regimens.

Keywords

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Grants

  1. UM1 AI068617/NIAID NIH HHS

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