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Journal of clinical medicine
Sep 10, 2024;13 (18):

Platelet Pathogen Reduction Technology-Should We Stay or Should We Go…?

Andrea Piccin, Allameddine Allameddine, Gilbert Spizzo, Katrina M Lappin, Daniele Prati
Author Information
  1. Andrea Piccin: Northern Ireland Blood Transfusion Service (NIBTS), Belfast BT9 7TS, UK. ORCID
  2. Allameddine Allameddine: Northern Ireland Blood Transfusion Service (NIBTS), Belfast BT9 7TS, UK.
  3. Gilbert Spizzo: Department of Oncology, Brixen Hospital, 39042 Bolzano, Italy.
  4. Katrina M Lappin: Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 1NN, UK. ORCID
  5. Daniele Prati: Servizio Trasfusionale, Ospedale Ca' Granda, 20122 Milano, Italy.
PMID: 39336845 DOI: 10.3390/jcm13185359

Abstract

The recent COVID-19 pandemic has significantly challenged blood transfusion services (BTS) for providing blood products and for keeping blood supplies available. The possibility that a similar pandemic event may occur again has induced researchers and transfusionists to investigate the adoption of new tools to prevent and reduce these risks. Similarly, increased donor travelling and globalization, with consequent donor deferral and donor pool reduction, have contributed to raising awareness on this topic. Although recent studies have validated the use of pathogen reduction technology (PRT) for the control of transfusion-transmitted infections (TTI) this method is not a standard of care despite increasing adoption. We present a critical commentary on the role of PRT for platelets and on associated problems for blood transfusion services (BTS). The balance of the cost effectiveness of adopting PRT is also discussed.

Keywords

INTERCEPT® MIRASOL® TA-GvHD THERAFLEX® amotosalen bacterial contaminations irradiation platelets riboflavin

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Journal Article

Word Cloud

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