A sustainable artificial-intelligence-augmented digital care pathway for epilepsy: Automating seizure tracking based on electroencephalogram data using artificial intelligence.

Pantea Keikhosrokiani, Minna Isomursu, Johanna Uusimaa, Jukka Kortelainen
Author Information
  1. Pantea Keikhosrokiani: Empirical Software Engineering in Software, Systems, and Services, University of Oulu, Oulu, Finland. ORCID
  2. Minna Isomursu: Empirical Software Engineering in Software, Systems, and Services, University of Oulu, Oulu, Finland.
  3. Johanna Uusimaa: Research Unit of Clinical Medicine and Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland.
  4. Jukka Kortelainen: Center for Machine Vision and Signal Analysis, University of Oulu, Oulu, Finland.

Abstract

Objective: Scalp electroencephalograms (EEGs) are critical for neurological evaluations, particularly in epilepsy, yet they demand specialized expertise that is often lacking in many regions. Artificial intelligence (AI) offers potential solutions to this gap. While existing AI models address certain aspects of EEG analysis, a fully automated system for routine EEG interpretation is required for effective epilepsy management and healthcare professionals' decision-making. This study aims to develop an AI-augmented model for automating EEG seizure tracking, thereby supporting a sustainable digital care pathway for epilepsy (DCPE). The goal is to improve patient monitoring, facilitate collaborative decision-making, ensure timely medication adherence, and promote patient compliance.
Method: The study proposes an AI-augmented framework using machine learning, focusing on quantitative analysis of EEG data to automate DCPE. A focus group discussion was conducted with healthcare professionals to find the problem of the current digital care pathway and assess the feasibility, usability, and sustainability of the AI-augmented system in the digital care pathway.
Results: The study found that a combination of random forest with principal component analysis and support vector machines with KBest feature selection achieved high accuracy rates of 96.52% and 95.28%, respectively. Additionally, the convolutional neural networks model outperformed other deep learning algorithms with an accuracy of 97.65%. The focus group discussion revealed that automating the diagnostic process in digital care pathway could reduce the time needed to diagnose epilepsy. However, the sustainability of the AI-integrated framework depends on factors such as technological infrastructure, skilled personnel, training programs, patient digital literacy, financial resources, and regulatory compliance.
Conclusion: The proposed AI-augmented system could enhance epilepsy management by optimizing seizure tracking accuracy, improving monitoring and timely interventions, facilitating collaborative decision-making, and promoting patient-centered care, thereby making the digital care pathway more sustainable.

Keywords

References

  1. Brain Sci. 2024 Feb 28;14(3): [PMID: 38539617]
  2. IEEE J Biomed Health Inform. 2024 Jun;28(6):3236-3247 [PMID: 38507373]
  3. Epilepsy Behav. 2020 Oct;111:107143 [PMID: 32554233]
  4. Int J Chron Obstruct Pulmon Dis. 2022 Jan 22;17:231-243 [PMID: 35095272]
  5. Epilepsy Behav. 2016 Sep;62:121-8 [PMID: 27454332]
  6. Nurs Open. 2023 Jul;10(7):4773-4785 [PMID: 36960773]
  7. Am J Manag Care. 2011 Jun;17 Suppl 7:S195-203 [PMID: 21761951]
  8. Front Neurol. 2018 Mar 02;9:99 [PMID: 29551988]
  9. Epilepsy Behav. 2020 May;106:107021 [PMID: 32224446]
  10. Seizure. 2023 Aug;110:11-20 [PMID: 37295277]
  11. Digit Health. 2023 Jan 11;9:20552076221150741 [PMID: 36655183]
  12. Epilepsy Behav. 2024 Jan;150:109571 [PMID: 38070408]
  13. Sci Rep. 2024 Apr 10;14(1):8424 [PMID: 38600209]
  14. Appl Clin Inform. 2016 Jul 06;7(3):633-45 [PMID: 27452661]
  15. JMIR Res Protoc. 2021 Mar 19;10(3):e25309 [PMID: 33739290]
  16. Seizure. 2023 Apr;107:155-161 [PMID: 37068328]
  17. Epilepsy Behav. 2024 Feb;151:109609 [PMID: 38160578]
  18. BMC Health Serv Res. 2022 Dec 30;22(1):1595 [PMID: 36585672]
  19. Comput Biol Med. 2020 Sep;124:103919 [PMID: 32771673]
  20. Epilepsy Behav. 2021 Jan;114(Pt A):107607 [PMID: 33248943]
  21. JMIR Res Protoc. 2024 Aug 6;13:e55123 [PMID: 39106484]
  22. Epilepsy Behav. 2023 Dec;149:109518 [PMID: 37952416]
  23. IEEE Trans Biomed Eng. 2016 Mar;63(3):664-75 [PMID: 26285054]

Word Cloud

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