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Journal of clinical hypertension (Greenwich, Conn.)
Jan, 2025;27 (1): e14941.

Physical Activity and Arterial Stiffness: A Narrative Review.

Jinyu Yang, Xiaoqian Chen, Xiang Chen, Lihua Li
Author Information
  1. Jinyu Yang: Department of Gerontology, The First Affiliated Hospital of Dali University, Dali, Yunnan Province, China.
  2. Xiaoqian Chen: Department of Gerontology, The First Affiliated Hospital of Dali University, Dali, Yunnan Province, China.
  3. Xiang Chen: Department of Gerontology, The First Affiliated Hospital of Dali University, Dali, Yunnan Province, China.
  4. Lihua Li: Department of Gerontology, The First Affiliated Hospital of Dali University, Dali, Yunnan Province, China. ORCID
PMID: 39552212 DOI: 10.1111/jch.14941

Abstract

Arterial stiffness is a significant predictor of cardiovascular disease and mortality. Physical activity (PA) has been extensively studied for its potential to reduce arterial stiffness, but the relationship between different types, durations, and intensities of PA and arterial stiffness remains a topic of ongoing research. Therefore, in this narrative review, we evaluated the current evidence focusing on the effect of PA on arterial stiffness and vascular health and discussed the known underlying physiological mechanisms. PA, irrespective of its intensity or pattern, is consistently associated with lower arterial stiffness. Aerobic exercise, particularly at higher intensities, is the most effective strategy for reducing arterial stiffness. These benefits are especially significant in populations with higher cardiovascular risk, such as those with type 2 diabetes mellitus and hypertension. Therefore, maintaining an active lifestyle into older age is crucial for vascular health and may contribute to healthy aging.

Keywords

arterial stiffness endothelial function oxidative stress physical activity vascular inflammation

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Grants

  1. 82260076/National Natural Science Foundation of China
  2. 81860084/National Natural Science Foundation of China
  3. /Xingdian Famous Physician Special Project of Yunnan Province
  4. /Youth Top-notch Talents Program of the Ten Thousand Talents Plan of Yunnan Province, Yunnan Key Specialties
  5. /Key Discipline of the First Affiliated Hospital of Dali University

MeSH Term

Vascular Stiffness
Humans
Exercise
Cardiovascular Diseases
Diabetes Mellitus, Type 2
Hypertension
Risk Factors
Male
Journal Article Review
Article has an altmetric score of 19

Word Cloud

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