The cost-effectiveness of a cash-based transfer, specialised nutritious food, and social and behaviour change communication intervention package to prevent undernutrition among children 6-23 months in Pakistan: A cluster randomised controlled trial.

Michael N Onah, Gul Nawaz Khan, Sumra Kureishy, Jessica Bourdaire, Saskia de Pee, Cecilia Garzon, Yasir Ihtesham, Naveed Akbar, Sajid Bashir Soofi
Author Information
  1. Michael N Onah: Institute of Public Policy and Administration, University of Central Asia.
  2. Gul Nawaz Khan: Centre of Excellence in Women & Child Health, Aga Khan University, Karachi, Pakistan.
  3. Sumra Kureishy: UN World Food Programme.
  4. Jessica Bourdaire: UN World Food Programme.
  5. Saskia de Pee: UN World Food Programme.
  6. Cecilia Garzon: UN World Food Programme.
  7. Yasir Ihtesham: UN World Food Programme.
  8. Naveed Akbar: Benazir Income Support Programme, Government of Pakistan, Pakistan.
  9. Sajid Bashir Soofi: Department of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan.

Abstract

Background: There is mixed evidence on the cost-effectiveness of cash transfers, along with food supplements and behaviour change communication interventions in improving child nutrition outcomes. To add to existing literature, we examined the cost-effectiveness of medium-quantity lipid-based nutrient supplement (LNS) and social and behaviour change communication (SBCC) messaging, separately and combined, compared to an existing unconditional cash transfers (UCT) programme in children 6-23 months of age in the district Rahim Yar Khan, Pakistan.
Methods: This was a four-arm, community-based cluster randomised controlled trial. The UCT provided a quarterly sum of USD 32, the medium-quantity LNS contained a daily ration of 50 g of LNS, and the SBCC included monthly and quarterly messaging on nutrition, health, and hygiene to eligible households. Cost data were collected from a provider perspective through the review of procurement invoices and budgets, as well as interviews with stakeholders. We examined cost-effectiveness via statistically significant differences between the intervention and control arms, and estimated as cost per case of stunting, and disability-adjusted life years (DALYs) averted at six and 18 months of intervention.
Results: Costs were higher for SBCC intervention combinations (UCT + SBCC and UCT + LNS + SBCC) due to high training costs for lady health workers. UCT + LNS achieved a reduction in stunting at a per-case cost of USDS 278.74 at six months and USD 897.15 at 18 months. UCT + LNS + SBCC achieved a reduction in stunting at per case cost of USD 846.48 at six months and USD 2324.58 at 18 months. The cost per DALYs averted for preventing stunting was USD 234 to USD 557.42 at six months, and USD 787.73 to USD 1537 at 18 months without discounting and age-weights.
Conclusions: Although the affordability of such interventions is arguable, combining UCTs with LNS appears to be very cost-effective for reducing undernutrition and averting DALYs, while combining cash transfers with LNS and SBCC showed limited cost-effectiveness when targeting stunting.
Registration: Clinicaltrials.gov: NCT03299218.

Associated Data

ClinicalTrials.gov | NCT03299218

References

  1. Lancet. 2008 Feb 16;371(9612):539-41 [PMID: 18280314]
  2. Lancet. 2013 Aug 3;382(9890):372-375 [PMID: 23746778]
  3. Public Health Nutr. 2018 Feb;21(2):273-287 [PMID: 29081315]
  4. Cochrane Database Syst Rev. 2015 Sep 11;(9):CD011247 [PMID: 26360970]
  5. Lancet. 2013 Aug 3;382(9890):452-477 [PMID: 23746776]
  6. PLoS One. 2017 Jun 21;12(6):e0179866 [PMID: 28636674]
  7. Lancet. 2008 Feb 16;371(9612):588-95 [PMID: 18280329]
  8. Nestle Nutr Workshop Ser Clin Perform Programme. 2001;5:1-14; discussion 14-8 [PMID: 11510433]
  9. Value Health. 2017 Feb;20(2):206-212 [PMID: 28237196]
  10. J Nutr. 2017 Jul;147(7):1410-1417 [PMID: 28539413]
  11. Med Decis Making. 2018 Oct;38(7):767-777 [PMID: 30248277]
  12. Pharmacoeconomics. 2019 Nov;37(11):1305-1312 [PMID: 31347104]
  13. Lancet Glob Health. 2014 Apr;2(4):e225-34 [PMID: 25103063]
  14. Am J Clin Nutr. 2022 Feb 9;115(2):492-502 [PMID: 34612491]
  15. Health Policy Plan. 2006 Jul;21(4):257-64 [PMID: 16672293]
  16. Lancet Glob Health. 2019 Sep;7(9):e1160-e1161 [PMID: 31401992]
  17. Trop Med Int Health. 2008 Nov;13(11):1405-14 [PMID: 18983270]
  18. Value Health. 2016 Dec;19(8):929-935 [PMID: 27987642]
  19. Proc Nutr Soc. 2017 Nov;76(4):580-588 [PMID: 28285607]
  20. Lancet. 2012 Oct 13;380(9850):1341-51 [PMID: 22999434]
  21. Lancet Child Adolesc Health. 2019 Nov;3(11):831-834 [PMID: 31521500]
  22. Health Policy Plan. 2018 Jul 1;33(6):743-754 [PMID: 29912462]
  23. Nutr Rev. 2003 May;61(5 Pt 1):168-75 [PMID: 12822705]
  24. Health Policy Plan. 2001 Sep;16(3):326-31 [PMID: 11527874]
  25. Nutr Res Rev. 2018 Jun;31(1):71-84 [PMID: 29113618]
  26. Am J Clin Nutr. 2017 Apr;105(4):944-957 [PMID: 28275125]
  27. BMC Pregnancy Childbirth. 2015 May 28;15:125 [PMID: 26018633]
  28. JAMA. 2004 Jun 2;291(21):2563-70 [PMID: 15173147]

MeSH Term

Female
Humans
Infant
Male
Cluster Analysis
Cost-Benefit Analysis
Malnutrition
Pakistan

Word Cloud

Created with Highcharts 10.0.0monthsUSDcost-effectivenessLNSstuntingSBCCinterventioncostsix18cashtransfersbehaviourchangecommunicationperDALYsfoodinterventionsnutritionexistingexaminedmedium-quantitysocialmessagingUCTchildren6-23clusterrandomisedcontrolledtrialquarterlyhealthcaseavertedUCT + LNS + SBCCachievedreductioncombiningundernutritionBackground:mixedevidencealongsupplementsimprovingchildoutcomesaddliteraturelipid-basednutrientsupplementseparatelycombinedcomparedunconditionalprogrammeagedistrictRahimYarKhanPakistanMethods:four-armcommunity-basedprovidedsum32containeddailyration50gincludedmonthlyhygieneeligiblehouseholdsCostdatacollectedproviderperspectivereviewprocurementinvoicesbudgetswellinterviewsstakeholdersviastatisticallysignificantdifferencescontrolarmsestimateddisability-adjustedlifeyearsResults:CostshighercombinationsUCT + SBCCduehightrainingcostsladyworkersUCT + LNSper-caseUSDS278748971584648232458preventing23455742787731537withoutdiscountingage-weightsConclusions:AlthoughaffordabilityarguableUCTsappearscost-effectivereducingavertingshowedlimitedtargetingRegistration:Clinicaltrialsgov:NCT03299218cash-basedtransferspecialisednutritiouspackagepreventamongPakistan:

Similar Articles

Cited By