Impact of Metabolites from Foodborne Pathogens on Cancer.

Alice N Mafe, Dietrich Büsselberg
Author Information
  1. Alice N Mafe: Department of Biological Sciences, Faculty of Sciences, Taraba State University, Main Campus, Jalingo 660101, Taraba State, Nigeria. ORCID
  2. Dietrich Büsselberg: Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha Metropolitan Area P.O. Box 22104, Qatar. ORCID

Abstract

Foodborne pathogens are microorganisms that cause illness through contamination, presenting significant risks to public health and food safety. This review explores the metabolites produced by these pathogens, including toxins and secondary metabolites, and their implications for human health, particularly concerning cancer risk. We examine various pathogens such as sp., sp., , and , detailing the specific metabolites of concern and their carcinogenic mechanisms. This study discusses analytical techniques for detecting these metabolites, such as chromatography, spectrometry, and immunoassays, along with the challenges associated with their detection. This study covers effective control strategies, including food processing techniques, sanitation practices, regulatory measures, and emerging technologies in pathogen control. This manuscript considers the broader public health implications of pathogen metabolites, highlighting the importance of robust health policies, public awareness, and education. This review identifies research gaps and innovative approaches, recommending advancements in detection methods, preventive strategies, and policy improvements to better manage the risks associated with foodborne pathogens and their metabolites.

Keywords

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Grants

  1. NPRP 14S0311-210033/Qatar National Reseach Fund

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