Tracheal tube infections in critical care: A narrative review of influencing factors, microbial agents, and mitigation strategies in intensive care unit settings.

Tahereh Motallebirad, Mohammad Reza Mohammadi, Ali Jadidi, Mehdi Safarabadi, Azam Kerami, Davood Azadi, Ehab Salam Hussein
Author Information
  1. Tahereh Motallebirad: Department of Research and Development, Satras Biotechnology Company, Khomein Branch, Islamic Azad University, Khomein, Iran.
  2. Mohammad Reza Mohammadi: Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  3. Ali Jadidi: Department of Nursing, School of Nursing, Arak University of Medical Sciences, Arak, Iran.
  4. Mehdi Safarabadi: Department of Nursing, Khomein University of Medical Sciences, Khomein, Iran. ORCID
  5. Azam Kerami: Department of Nursing, Khomein University of Medical Sciences, Khomein, Iran.
  6. Davood Azadi: Department of Biology, Faculty of Basic Sciences, Lorestan University, Khorramabad, Iran. ORCID
  7. Ehab Salam Hussein: Pharmacy Department, Al-Amarah University College, Missan, Iraq.

Abstract

Tracheal tube infections pose significant challenges in the management of mechanically ventilated patients in intensive care units. These infections contribute to prolonged intensive care unit stays, increased healthcare costs, the spread of antibiotic resistance, and poor patient outcomes. This study aims to elucidate the complex relationship between environmental factors, hospital practices, and the incidence of Tracheal tube infections. Our comprehensive review explores the impact of factors such as air quality, water sources, equipment contamination, ventilation strategies, infection control protocols, and microbial reservoirs within hospital settings on tracheal tube infection rates. Additionally, it investigates global variations in tracheal tube infection prevalence, which are influenced by differences in healthcare infrastructure, infection control adherence, antibiotic resistance profiles, and patient demographics. Our findings highlight the importance of targeted interventions and collaborative approaches to reduce the burden of Tracheal tube infections and improve patient care in intensive care units. By fully understanding the interplay between environmental conditions and hospital practices, effective prevention and management strategies can be developed to reduce the impact of Tracheal tube infections on patient outcomes and healthcare resources, ultimately enhancing the quality of care in critical care settings.

Keywords

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