Maternal mortality estimation methodologies: a scoping review and evaluation of suitability for use in humanitarian settings.

Blake Erhardt-Ohren, Sandra I McCoy, Dennis M Feehan, Rohini J Haar, Ndola Prata
Author Information
  1. Blake Erhardt-Ohren: Bixby Center for Population, Health and Sustainability, School of Public Health, University of California, Berkeley, Berkeley, USA. berhardt-ohren@berkeley.edu.
  2. Sandra I McCoy: Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, USA.
  3. Dennis M Feehan: Department of Demography, University of California, Berkeley, Berkeley, USA.
  4. Rohini J Haar: Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, USA.
  5. Ndola Prata: Bixby Center for Population, Health and Sustainability, School of Public Health, University of California, Berkeley, Berkeley, USA.

Abstract

BACKGROUND: Around the world, a maternal death occurs approximately every two minutes-most of these deaths are preventable. The maternal mortality ratio is a key indicator for the Sustainable Development Goals, yet we have no reliable way to estimate maternal deaths in refugee or internally displaced persons (IDP) camps and settlements. The goal of this study was to understand the methodologies most suited for adaptation for use to estimate the proportion of maternal mortality due to abortion complications in these settings.
METHODS: We conducted a scoping review of methodologies to estimate maternal mortality and evaluated them using a predetermined set of criteria. We evaluated nine original methodologies using eleven categories related to implementation in refugee or IDP camps and settlements: data sources, definitions, sample size, timing of point estimate relative to data collection, bias, human resources, time needed for implementation, data collection training, statistical training, digitalization, and cost. Each category could be assigned zero to four points, for a total score of 44 points. After evaluating each original methodology, we reviewed the original publication's citations or searched for other implementations through October 2022. We revised the original scores and developed a rank-order list of the methodologies according to their suitability for implementation in refugee and IDP camps.
RESULTS: We identified 124 publications that estimated maternal mortality. The Maternal Deaths from Informants/Maternal Death Follow on Review (MADE-IN/MADE-FOR) (33.5), hospital- or facility-based (33.5), and community informant-based (32.5) methodologies ranked highest due to low costs, short time interval needed for implementation, small sample sizes and close timing of point estimate relative to data collection, easy digitalization, and the need for no statistical training.
DISCUSSION: Similar to the lack of a "perfect" methodology to estimate maternal mortality in stable settings, there are compromises to consider when applying these methodologies to humanitarian settings. The most promising methodologies are adaptable to practical constraints in refugee and IDP camps and settlements. New methodologies that adapt and strengthen the MADE-IN/MADE-FOR, hospital- or facility-based, and community informant-based methodology show promise and must be further developed.

Keywords

References

  1. Indian J Med Res. 2011 Jan;133:64-9 [PMID: 21321421]
  2. Sex Reprod Health Matters. 2019 May;27(2):1610275 [PMID: 31533592]
  3. Lancet. 2002 Feb 23;359(9307):643-9 [PMID: 11879858]
  4. Int J Epidemiol. 1988 Jun;17(2):385-91 [PMID: 3403135]
  5. BMC Med. 2008 May 26;6:12 [PMID: 18503716]
  6. PLoS Curr. 2014 Mar 18;6: [PMID: 24818066]
  7. Int J Gynaecol Obstet. 2023 Feb;160(2):483-491 [PMID: 36217727]
  8. Int Perspect Sex Reprod Health. 2020 Dec 14;46(Suppl 1):77-81 [PMID: 33326402]
  9. JAMA. 2002 Aug 7;288(5):595-603 [PMID: 12150671]
  10. PLoS One. 2014 Jan 02;9(1):e83590 [PMID: 24392088]
  11. Int J Gynaecol Obstet. 2012 Sep;118 Suppl 2:S107-12 [PMID: 22920613]
  12. Health Policy Plan. 2018 Dec 1;33(10):1107-1117 [PMID: 30534942]
  13. Lancet. 2022 Feb 26;399(10327):803-813 [PMID: 35182472]
  14. BMC Pregnancy Childbirth. 2018 Oct 11;18(1):396 [PMID: 30305058]
  15. Lancet Glob Health. 2014 Jun;2(6):e323-33 [PMID: 25103301]
  16. BMC Pregnancy Childbirth. 2023 Mar 4;23(1):143 [PMID: 36871004]
  17. Br Med Bull. 2017 Jan 1;121(1):121-134 [PMID: 28104630]
  18. BMC Health Serv Res. 2018 Nov 29;18(1):909 [PMID: 30497464]
  19. Stud Fam Plann. 1989 May-Jun;20(3):125-35 [PMID: 2734809]
  20. BMC Womens Health. 2019 Dec 9;19(1):155 [PMID: 31815617]
  21. Lancet. 2002 Dec;360 Suppl:s13-4 [PMID: 12504485]
  22. Front Glob Womens Health. 2021 Sep 21;2:699121 [PMID: 34816236]
  23. PLoS One. 2013;8(1):e53346 [PMID: 23341939]
  24. Ann Intern Med. 2018 Oct 2;169(7):467-473 [PMID: 30178033]
  25. Rev Bras Ginecol Obstet. 2018 Jun;40(6):309-312 [PMID: 29895089]
  26. Afr J Reprod Health. 2020 Sep;24(3):51-58 [PMID: 34077127]
  27. Int J Gynaecol Obstet. 1988 Feb;26(1):21-32 [PMID: 2892734]
  28. Am J Public Health. 1986 Feb;76(2):134-8 [PMID: 3946693]
  29. Int J Gynaecol Obstet. 2022 Oct;159(1):166-172 [PMID: 34890470]
  30. Disasters. 2018 Oct;42(4):619-634 [PMID: 29532956]
  31. Int Perspect Sex Reprod Health. 2012 Dec;38(4):205-13 [PMID: 23318170]

Word Cloud

Created with Highcharts 10.0.0mortalitymethodologiesmaternalestimaterefugeeIDPcampssettingsoriginalimplementationdatacollectiontrainingmethodologyMaternal5deathsdisplacedsettlementsuseduescopingreviewevaluatedusingsampletimingpointrelativetimeneededstatisticaldigitalizationpointsdevelopedsuitabilityMADE-IN/MADE-FOR33hospital-facility-basedcommunityinformant-basedhumanitarianestimationBACKGROUND:Aroundworlddeathoccursapproximatelyeverytwominutes-mostpreventableratiokeyindicatorSustainableDevelopmentGoalsyetreliablewayinternallypersonsgoalstudyunderstandsuitedadaptationproportionabortioncomplicationsMETHODS:conductedpredeterminedsetcriterianineelevencategoriesrelatedsettlements:sourcesdefinitionssizebiashumanresourcescostcategoryassignedzerofourtotalscore44evaluatingreviewedpublication'scitationssearchedimplementationsOctober2022revisedscoresrank-orderlistaccordingRESULTS:identified124publicationsestimatedDeathsInformants/MaternalDeathFollowReview32rankedhighestlowcostsshortintervalsmallsizescloseeasyneedDISCUSSION:Similarlack"perfect"stablecompromisesconsiderapplyingpromisingadaptablepracticalconstraintsNewadaptstrengthenshowpromisemustmethodologies:evaluationAbortionCapturerecaptureEstimationForciblyMeasurementMultiplesystemsRAMOSRefugeeReproductiveagesurveyTerminationpregnancy

Similar Articles

Cited By

No available data.