Multiple forms of discrimination and obsessive-compulsive disorder: a prospective cohort study.

Jason M Nagata, Jonanne Talebloo, Thang Diep, Joan Shim, Abubakr A A Al-Shoaibi, Kyle T Ganson, Alexander Testa, Jinbo He, Jason M Lavender, Fiona C Baker
Author Information
  1. Jason M Nagata: Department of Pediatrics, University of California, San Francisco, 550 16th Street, 4th Floor, Box 0503, San Francisco, CA, 94143, USA. jason.nagata@ucsf.edu.
  2. Jonanne Talebloo: Department of Pediatrics, University of California, San Francisco, 550 16th Street, 4th Floor, Box 0503, San Francisco, CA, 94143, USA.
  3. Thang Diep: Department of Pediatrics, University of California, San Francisco, 550 16th Street, 4th Floor, Box 0503, San Francisco, CA, 94143, USA.
  4. Joan Shim: Department of Pediatrics, University of California, San Francisco, 550 16th Street, 4th Floor, Box 0503, San Francisco, CA, 94143, USA.
  5. Abubakr A A Al-Shoaibi: Department of Pediatrics, University of California, San Francisco, 550 16th Street, 4th Floor, Box 0503, San Francisco, CA, 94143, USA.
  6. Kyle T Ganson: Factor-Inwentash Faculty of Social Work, University of Toronto, 246 Bloor St W, Toronto, ON, M5S 1V4, Canada.
  7. Alexander Testa: Department of Management, Policy and Community Health, University of Texas Health Science Center at Houston, 1200 Pressler Street, Houston, TX, 77030, USA.
  8. Jinbo He: Division of Applied Psychology, School of Humanities and Social Science, The Chinese University of Hong Kong, Shenzhen, 518172, Guangdong, China.
  9. Jason M Lavender: Military Cardiovascular Outcomes Research Program (MiCOR), Department of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.
  10. Fiona C Baker: Center for Health Sciences, SRI International, 333 Ravenswood Ave, Menlo Park, CA, 94025, USA.

Abstract

BACKGROUND: Discrimination increases the risk for adverse mental health in minority populations, with studies showing elevated rates of obsessive-compulsive disorder (OCD) in Black adults facing racial discrimination. Yet, there is a lack of longitudinal research on the different forms of discrimination in relation to OCD risk in early adolescence. The objective of this study was to examine the prospective associations between multiple forms of discrimination and OCD in a national sample of U.S. early adolescents.
METHODS: We examined prospective cohort data from Year 2 (2018-2020, ages 10-13) and Year 3 (2019-2021) of the Adolescent Brain Cognitive Development Study (N = 7,983). Multiple logistic regression models were used to analyze associations between Year 2 past 12-month experiences of discrimination (based on race and ethnicity, country of origin, sexual orientation, weight, and combined multi-discrimination) and Year 3 probable OCD (Child Behavior Checklist; based on dichotomized t-score indicating high risk), adjusting for theoretically relevant covariates including age, sex, sexual orientation, race and ethnicity, country of origin, household income, parent education, depression, body mass index category, study site, and Year 2 probable OCD.
RESULTS: Adjusting for all covariates, multi-discrimination (OR = 1.67; 95% CI 1.23, 2.27), racial discrimination (OR = 2.77; 95% CI 1.32, 5.80), sexual orientation discrimination (OR = 2.51; 95% CI 1.11, 5.64), and weight discrimination (OR = 2.51; 95% CI 1.13, 5.59) at Year 2 were prospectively associated with developing probable OCD at Year 3. There were no significant findings for discrimination based on country of origin.
CONCLUSIONS: Early adolescents who have experienced several forms of discrimination have higher odds of developing probable OCD, suggesting the utility of screening for OCD in even younger adolescents who have encountered discrimination. Educators can play a role in guiding adolescents experiencing discrimination to appropriate resources for accessing mental healthcare.

Keywords

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Grants

  1. R01MH135492/NIH HHS
  2. K08 HL159350/NHLBI NIH HHS
  3. 2022056/Doris Duke Charitable Foundation
  4. R01 MH135492/NIMH NIH HHS
  5. K08HL1549350/NIH HHS

Word Cloud

Created with Highcharts 10.0.0discriminationOCDYear2formsadolescentsprobable95%CI1riskstudyprospective3basedcountryoriginsexualorientationOR = 25Discriminationmentalobsessive-compulsivedisorderracialearlyassociationscohortAdolescentMultipleraceethnicityweightmulti-discriminationcovariates51developingBACKGROUND:increasesadversehealthminoritypopulationsstudiesshowingelevatedratesBlackadultsfacingYetlacklongitudinalresearchdifferentrelationadolescenceobjectiveexaminemultiplenationalsampleUSMETHODS:examineddata2018-2020ages10-132019-2021BrainCognitiveDevelopmentStudyN = 7983logisticregressionmodelsusedanalyzepast12-monthexperiencescombinedChildBehaviorChecklistdichotomizedt-scoreindicatinghighadjustingtheoreticallyrelevantincludingagesexhouseholdincomeparenteducationdepressionbodymassindexcategorysiteRESULTS:AdjustingOR = 167232777328011641359prospectivelyassociatedsignificantfindingsCONCLUSIONS:EarlyexperiencedseveralhigheroddssuggestingutilityscreeningevenyoungerencounteredEducatorscanplayroleguidingexperiencingappropriateresourcesaccessinghealthcaredisorder:AdolescenceObsessive-compulsivePrejudiceRacismStigma

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