Samuel W Hawes, Andrew K Littlefield, Daniel A Lopez, Kenneth J Sher, Erin L Thompson, Raul Gonzalez, Laika Aguinaldo, Ashley R Adams, Mohammadreza Bayat, Amy L Byrd, Luis Fs Castro-de-Araujo, Anthony Dick, Steven F Heeringa, Christine M Kaiver, Sarah M Lehman, Lin Li, Janosch Linkersd��rfer, Thomas J Maullin-Sapey, Michael C Neale, Thomas E Nichols, Samantha Perlstein, Susan F Tapert, Colin E Vize, Margot Wagner, Rebecca Waller, Wesley K Thompson
Author Information
Samuel W Hawes: Center for Children & Families, Florida International University, Miami, FL, USA. Electronic address: shawes@fiu.edu.
Andrew K Littlefield: Psychological Sciences, Texas Tech University, Lubbock, TX, USA. Electronic address: andrew.littlefield@ttu.edu.
Daniel A Lopez: Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA. Electronic address: lopdanie@ohsu.edu.
Kenneth J Sher: Psychological Sciences, University of Missouri, Columbia, MO, USA. Electronic address: SherK@missouri.edu.
Erin L Thompson: Center for Children & Families, Florida International University, Miami, FL, USA. Electronic address: erthomps@fiu.edu.
Raul Gonzalez: Center for Children & Families, Florida International University, Miami, FL, USA. Electronic address: gonzara@fiu.edu.
Laika Aguinaldo: Department of Psychiatry, University of California San Diego, San Diego, CA, USA. Electronic address: laaguinaldo@health.ucsd.edu.
Ashley R Adams: Center for Children & Families, Florida International University, Miami, FL, USA. Electronic address: asadams@fiu.edu.
Mohammadreza Bayat: Center for Children & Families, Florida International University, Miami, FL, USA. Electronic address: mbayat@fiu.edu.
Amy L Byrd: Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: byrdal@upmc.edu.
Luis Fs Castro-de-Araujo: Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: Luis.Araujo@vcuhealth.org.
Anthony Dick: Cognitive Neuorscience, Florida International University, Miami, FL, USA. Electronic address: adick@fiu.edu.
Steven F Heeringa: Institute for Social Research, University of Michigan, Ann Arbor, MI, USA. Electronic address: sheering@umich.edu.
Christine M Kaiver: Center for Children & Families, Florida International University, Miami, FL, USA. Electronic address: ckaiv001@fiu.edu.
Sarah M Lehman: Center for Children & Families, Florida International University, Miami, FL, USA. Electronic address: slehman@fiu.edu.
Lin Li: Department of Radiology, University of California San Diego, San Diego, CA, USA. Electronic address: lil033@ucsd.edu.
Janosch Linkersd��rfer: Center for Human Development, University of California San Diego, San Diego, CA, USA. Electronic address: jlinkersdoerfer@ucsd.edu.
Thomas J Maullin-Sapey: School of Mathematics, University of Bristol, Bristol, United Kingdom. Electronic address: Thomas.Maullin-Sapey@bristol.ac.uk.
Michael C Neale: Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: Michael.Neale@vcuhealth.org.
Thomas E Nichols: Oxford Big Data Institute, University of Oxford, Oxford, United Kingdom. Electronic address: thomas.nichols@bdi.ox.ac.uk.
Samantha Perlstein: Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: sperl@sas.upenn.edu.
Susan F Tapert: Department of Psychiatry, University of California San Diego, San Diego, CA, USA. Electronic address: stapert@ucsd.edu.
Colin E Vize: Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: CEV18@pitt.edu.
Margot Wagner: The Institute for Neural Computation, University of California San Diego, San Diego, CA, USA. Electronic address: mwagner@ucsd.edu.
Rebecca Waller: Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: rwaller@sas.upenn.edu.
Wesley K Thompson: Center for Population Neuroscience and Genetics, Laureate Institute for Brain Research, Tulsa, OK, USA. Electronic address: wes.stat@gmail.com.
The Adolescent Brain Cognitive Development�� (ABCD) Study provides a unique opportunity to investigate developmental processes in a large, diverse cohort of youths, aged approximately 9-10 at baseline and assessed annually for 10 years. Given the size and complexity of the ABCD Study, researchers analyzing its data will encounter a myriad of methodological and analytical considerations. This review provides an examination of key concepts and techniques related to longitudinal analyses of the ABCD Study data, including: (1) characterization of the factors associated with variation in developmental trajectories; (2) assessment of how level and timing of exposures may impact subsequent development; (3) quantification of how variation in developmental domains may be associated with outcomes, including mediation models and reciprocal relationships. We emphasize the importance of selecting appropriate statistical models to address these research questions. By presenting the advantages and potential challenges of longitudinal analyses in the ABCD Study, this review seeks to equip researchers with foundational knowledge and tools to make informed decisions as they navigate and effectively analyze and interpret the multi-dimensional longitudinal data currently available.
