Brassinosteroids (BRs) are crucial plant hormones that play a significant role in regulating various physiological processes, including micronutrient homeostasis. This review delves into the complex roles of BRs in the uptake, distribution, and utilization of essential micronutrients such as iron (Fe), zinc (Zn), manganese (Mn), copper (Cu), and boron (B). BRs influence the expression of key transporter genes responsible for the absorption and internal distribution of these micronutrients. For iron, BRs enhance the expression of genes related to iron reduction and transport, improve root architecture, and strengthen stress tolerance mechanisms. Regarding zinc, BRs regulate the expression of zinc transporters and support root development, thereby optimizing zinc uptake. Manganese homeostasis is managed through the BR-mediated regulation of manganese transporter genes and chlorophyll production, essential for photosynthesis. For copper, BRs influence the expression of copper transporters and maintain copper-dependent enzyme activities crucial for metabolic functions. Finally, BRs contribute to boron homeostasis by regulating its metabolism, which is vital for cell wall integrity and overall plant development. This review synthesizes recent findings on the mechanistic pathways through which BRs affect micronutrient homeostasis and discusses their implications for enhancing plant nutrition and stress resilience. Understanding these interactions offers valuable insights into strategies for improving micronutrient efficiency in crops, which is essential for sustainable agriculture. This comprehensive analysis highlights the significance of BRs in micronutrient management and provides a framework for future research aimed at optimizing nutrient use and boosting plant productivity.
