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Plant biotechnology (Tokyo, Japan)
Sep 25, 2024;41 (3): 173-193.

Synthetic biology in plants.

Takahiko Hayakawa, Hayato Suzuki, Hiroshi Yamamoto, Nobutaka Mitsuda
Author Information
  1. Takahiko Hayakawa: Mitsubishi Chemical Research Corporation, 16-1 Samon-cho, Sinjuku-ku, Tokyo 106-0017, Japan.
  2. Hayato Suzuki: Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukisamu Higashi 2-17-2-1, Toyohira, Sapporo, Hokkaido 062-8517, Japan.
  3. Hiroshi Yamamoto: Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, Higashi 1-1-1, Tsukuba, Ibaraki 305-8566, Japan.
  4. Nobutaka Mitsuda: Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukisamu Higashi 2-17-2-1, Toyohira, Sapporo, Hokkaido 062-8517, Japan.
PMID: 40115764 DOI: 10.5511/plantbiotechnology.24.0630b

Abstract

Synthetic biology, an interdisciplinary field at the intersection of engineering and biology, has garnered considerable attention for its potential applications in plant science. By exploiting engineering principles, synthetic biology enables the redesign and construction of biological systems to manipulate plant traits, metabolic pathways, and responses to environmental stressors. This review explores the evolution and current state of synthetic biology in plants, highlighting key achievements and emerging trends. Synthetic biology offers innovative solutions to longstanding challenges in agriculture and biotechnology for improvement of nutrition and photosynthetic efficiency, useful secondary metabolite production, engineering biosensors, and conferring stress tolerance. Recent advances, such as genome editing technologies, have facilitated precise manipulation of plant genomes, creating new possibilities for crop improvement and sustainable agriculture. Despite its transformative potential, ethical and biosafety considerations underscore the need for responsible deployment of synthetic biology tools in plant research and development. This review provides insights into the burgeoning field of plant synthetic biology, offering a glimpse into its future implications for food security, environmental sustainability, and human health.

Keywords

lignocellulose luminescent plants photosynthesis secondary metabolites synthetic biology

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Created with Highcharts 10.0.0biologyplantsyntheticSyntheticengineeringplantsfieldpotentialenvironmentalreviewagricultureimprovementsecondaryinterdisciplinaryintersectiongarneredconsiderableattentionapplicationsscienceexploitingprinciplesenablesredesignconstructionbiologicalsystemsmanipulatetraitsmetabolicpathwaysresponsesstressorsexploresevolutioncurrentstatehighlightingkeyachievementsemergingtrendsoffersinnovativesolutionslongstandingchallengesbiotechnologynutritionphotosyntheticefficiencyusefulmetaboliteproductionbiosensorsconferringstresstoleranceRecentadvancesgenomeeditingtechnologiesfacilitatedprecisemanipulationgenomescreatingnewpossibilitiescropsustainableDespitetransformativeethicalbiosafetyconsiderationsunderscoreneedresponsibledeploymenttoolsresearchdevelopmentprovidesinsightsburgeoningofferingglimpsefutureimplicationsfoodsecuritysustainabilityhumanhealthlignocelluloseluminescentphotosynthesismetabolites

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