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Found 411 results

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The unbalanced p53/SIRT1 axis may impact lymphocyte homeostasis in COVID-19 patients.
Veronica Bordoni, Eleonora Tartaglia, Alessandra Sacchi, Gian Maria Fimia, Eleonora Cimini, Rita Casetti, Stefania Notari, Germana Grassi, Luisa Marchioni, Michele Bibas, Maria R Capobianchi, Franco Locatelli, Markus Maeurer, Alimuddin Zumla, Andrea Antinori, Emanuele Nicastri, Giuseppe Ippolito, Chiara Agrati
Int J Infect Dis. Apr, 2021.105:49-53 Print-Electronic
Source:PubMed
PMID: 33578018 doi:10.1016/j.ijid.2021.02.019
The effect of the G1-S transition checkpoint on an age structured cell cycle model.
Gary S Chaffey, David J B Lloyd, Anne C Skeldon, Norman F Kirkby
PLoS One. 2014.9(1):e83477 Electronic-eCollection
Source:PubMed
PMID: 24416166 doi:10.1371/journal.pone.0083477
Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice.
Qing-Shuo Zhang, Kevin Watanabe-Smith, Kathryn Schubert, Angela Major, Andrea M Sheehan, Laura Marquez-Loza, Amy E Hanlon Newell, Eric Benedetti, Eric Joseph, Susan Olson, Markus Grompe
Stem Cell Res. Sep, 2013.11(2):687-92 Print-Electronic
Source:PubMed
PMID: 23721813 doi:10.1016/j.scr.2013.04.010
p21 protects "Super p53" mice from the radiation-induced gastrointestinal syndrome.
Julie M Sullivan, Laura B Jeffords, Chang-Lung Lee, Rafaela Rodrigues, Yan Ma, David G Kirsch
Radiat Res. Mar, 2012.177(3):307-10 Print-Electronic
Source:PubMed
PMID: 22165824 doi:10.1667/rr2545.1
Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53.
L Resnick-Silverman, S St Clair, M Maurer, K Zhao, J J Manfredi
Genes Dev. Jul 15, 1998.12(14):2102-7 Print
Source:PubMed
PMID: 9679054 doi:10.1101/gad.12.14.2102
Cooperative effects of genes controlling the G(2)/M checkpoint.
T A Chan, P M Hwang, H Hermeking, K W Kinzler, B Vogelstein
Genes Dev. Jul 01, 2000.14(13):1584-8 Print
Source:PubMed
PMID: 10887152 doi:
Effects of the protein kinase inhibitors wortmannin and KN62 on cellular radiosensitivity and radiation-activated S phase and G1/S checkpoints in normal human fibroblasts.
L Enns, D Murray, R Mirzayans
Br J Cancer. Nov, 1999.81(6):959-65 Print
Source:PubMed
PMID: 10576651 doi:10.1038/sj.bjc.6690793
The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage.
Paolo Salomoni, Rosa Bernardi, Stephan Bergmann, Austin Changou, Sara Tuttle, Pier Paolo Pandolfi
Blood. May 01, 2005.105(9):3686-90 Print-Electronic
Source:PubMed
PMID: 15626733 doi:10.1182/blood-2004-09-3782
Apoptosis is the essential target of selective pressure against p53, whereas loss of additional p53 functions facilitates carcinoma progression.
Xiangdong Lu, Chunyu Yang, Chaoying Yin, Terry Van Dyke, Karl Simin
Mol Cancer Res. Apr, 2011.9(4):430-9 Print-Electronic
Source:PubMed
PMID: 21385880 doi:10.1158/1541-7786.MCR-10-0277
Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation.
Verena Labi, Miriam Erlacher, Gerhard Krumschnabel, Claudia Manzl, Alexandar Tzankov, Josephina Pinon, Alexander Egle, Andreas Villunger
Genes Dev. Aug 01, 2010.24(15):1602-7 Print
Source:PubMed
PMID: 20679395 doi:10.1101/gad.1940210
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