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humanized mice
Stable Engraftment of a Human Gut Bacterial Microbiome in Double Humanized BLT-mice
Daharsh, L.; Ramer-Tait, A.; Li, Q.
biorxiv
. 2019-08-29. Preprint
Source:biorxiv
PPRID:
10.1101/749093v1
doi:NA
The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers.
Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Hiroaki Kato, Hiroshi Yamazaki, Hiroshi Suemizu
Drug Metab Dispos
. 04, 2023.51(4):480-491 Print-Electronic
Source:PubMed
PMID:
36623885
doi:10.1124/dmd.122.001102
Cytochrome P450s in chimeric mice with humanized liver.
Shotaro Uehara, Hiroshi Suemizu, Hiroshi Yamazaki
Adv Pharmacol
. 2022.95:307-328 Print-Electronic
Source:PubMed
PMID:
35953159
doi:10.1016/bs.apha.2022.05.004
Humanized mice: A brief overview on their diverse applications in biomedical research.
Shigeyoshi Fujiwara
J Cell Physiol
. 04, 2018.233(4):2889-2901 Print-Electronic
Source:PubMed
PMID:
28543438
doi:10.1002/jcp.26022
SGX523 causes renal toxicity through aldehyde oxidase-mediated less-soluble metabolite formation in chimeric mice with humanized livers.
Shotaro Uehara, Masahiko Yasuda, Yuichiro Higuchi, Nao Yoneda, Kenji Kawai, Masami Suzuki, Hiroshi Yamazaki, Hiroshi Suemizu
Toxicol Lett
. Oct 01, 2023.388:48-55 Print-Electronic
Source:PubMed
PMID:
37806366
doi:10.1016/j.toxlet.2023.10.003
Different Hepatic Concentrations of Bromobenzene, 1,2-Dibromobenzene, and 1,4-Dibromobenzene in Humanized-Liver Mice Predicted Using Simplified Physiologically Based Pharmacokinetic Models as Putative Markers of Toxicological Potential.
Tomonori Miura, Makiko Shimizu, Shotaro Uehara, Manae Yoshizawa, Ayane Nakano, Mayu Yanagi, Yusuke Kamiya, Norie Murayama, Hiroshi Suemizu, Hiroshi Yamazaki
Chem Res Toxicol
. 12 21, 2020.33(12):3048-3053 Print-Electronic
Source:PubMed
PMID:
33283517
doi:10.1021/acs.chemrestox.0c00387
Cytochrome P450-dependent drug oxidation activities and their expression levels in liver microsomes of chimeric TK-NOG mice with humanized livers.
Shotaro Uehara, Nao Yoneda, Yuichiro Higuchi, Hiroshi Yamazaki, Hiroshi Suemizu
Drug Metab Pharmacokinet
. Jun, 2022.44:100454 Print-Electronic
Source:PubMed
PMID:
35378494
doi:10.1016/j.dmpk.2022.100454
Modeling malaria in humanized mice: opportunities and challenges.
Evelyn Siu, Alexander Ploss
Ann N Y Acad Sci
. Apr, 2015.1342:29-36 Print-Electronic
Source:PubMed
PMID:
25678404
doi:10.1111/nyas.12618
Editorial: Development of Humanized Mouse Models for Infectious Diseases and Cancer.
Moriya Tsuji, Ramesh Akkina
Front Immunol
. 2019.10:3051 Electronic-eCollection
Source:PubMed
PMID:
31998319
doi:10.3389/fimmu.2019.03051
Humanized mouse models: Application to human diseases.
Ryoji Ito, Takeshi Takahashi, Mamoru Ito
J Cell Physiol
. 05, 2018.233(5):3723-3728 Print-Electronic
Source:PubMed
PMID:
28598567
doi:10.1002/jcp.26045
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