LGC characterizes and identifies lncRNAs based on the relationship between ORF (open reading frame) Length and GC content. LGC is able to accurately distinguish lncRNAs from protein-coding RNAs in a cross-species manner without species-specific adjustments, and is robustly effective (>90% accuracy) in discriminating lncRNAs from protein-coding RNAs across diverse species that range from plants to mammals.
A web server for online identification of lncRNAs is publicly available at http://bigd.big.ac.cn/lgc/calculator.
- Lina Ma firstname.lastname@example.org Developer
BIGD, Beijing Institute of Genomics, Chinese Academy of Sciences, China
- Zhang Zhang email@example.com Developer
BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, China
- Guangyu Wang firstname.lastname@example.org Developer
The Methodist Hospital Research Institute, The Methodist Hospital Research Institute, China
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