Introduction

We introduce the Mindboggle-101 dataset, the largest and most complete set of free, publicly accessible, manually labeled human brain images. To manually label the macroscopic anatomy in magnetic resonance images of 101 healthy participants, we created a new cortical labeling protocol that relies on robust anatomical landmarks and minimal manual edits after initialization with automated labels. The "Desikan-Killiany-Tourville" (DKT) protocol is intended to improve the ease, consistency, and accuracy of labeling human cortical areas. Given how difficult it is to label brains, the Mindboggle-101 dataset is intended to serve as brain atlases for use in labeling other brains, as a normative dataset to establish morphometric variation in a healthy population for comparison against clinical populations, and contribute to the development, training, testing, and evaluation of automated registration and labeling algorithms. To this end, we also introduce benchmarks for the evaluation of such algorithms by comparing our manual labels with labels automatically generated by probabilistic and multi-atlas registration-based approaches. All data and related software and updated information are available on the http://mindboggle.info/data website.

Publications

  1. 101 labeled brain images and a consistent human cortical labeling protocol.
    Cite this
    Klein A, Tourville J, 2012-01-01 - Frontiers in neuroscience
  2. Mindboggle: automated brain labeling with multiple atlases.
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    Klein A, Mensh B, Ghosh S, Tourville J, Hirsch J, 2005-10-01 - BMC medical imaging
  3. Mindboggle: a scatterbrained approach to automate brain labeling.
    Cite this
    Klein A, Hirsch J, 2005-01-01 - NeuroImage

Credits

  1. Arno Klein
    Developer

    Department of Psychiatry and Behavioral Science, Stony Brook University School of Medicine Stony Brook, United States of America

  2. Jason Tourville
    Investigator

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Summary
AccessionBT000760
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesC++
User InterfaceTerminal Command Line
Download Count0
Submitted ByJason Tourville